TNF biology, pathogenic mechanisms and emerging therapeutic strategies GD Kalliolias, LB Ivashkiv Nature reviews rheumatology 12 (1), 49-62, 2016 | 1321 | 2016 |
Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis F Mizoguchi, K Slowikowski, K Wei, JL Marshall, DA Rao, SK Chang, ... Nature communications 9 (1), 789, 2018 | 450 | 2018 |
iRHOM2 is a critical pathogenic mediator of inflammatory arthritis PDA Issuree, T Maretzky, DR McIlwain, S Monette, X Qing, PA Lang, ... The Journal of clinical investigation 123 (2), 928-932, 2013 | 197 | 2013 |
Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins L Wang, RA Gordon, L Huynh, X Su, KHP Min, J Han, JS Arthur, ... Immunity 32 (4), 518-530, 2010 | 159 | 2010 |
IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38 GD Kalliolias, LB Ivashkiv The Journal of Immunology 180 (9), 6325-6333, 2008 | 159 | 2008 |
Proliferative lesions and metalloproteinase activity in murine lupus nephritis mediated by type I interferons and macrophages A Triantafyllopoulou, CW Franzke, SV Seshan, G Perino, GD Kalliolias, ... Proceedings of the National Academy of Sciences 107 (7), 3012-3017, 2010 | 158 | 2010 |
Tumor necrosis factor α induces sustained signaling and a prolonged and unremitting inflammatory response in rheumatoid arthritis synovial fibroblasts A Lee, Y Qiao, G Grigoriev, J Chen, KH Park‐Min, SH Park, LB Ivashkiv, ... Arthritis & Rheumatism 65 (4), 928-938, 2013 | 150 | 2013 |
The future of the IL-1 receptor antagonist anakinra: from rheumatoid arthritis to adult-onset Still's disease and systemic-onset juvenile idiopathic arthritis GD Kalliolias, SN C Liossis Expert opinion on investigational drugs 17 (3), 349-359, 2008 | 133 | 2008 |
Overview of the biology of type I interferons GD Kalliolias, LB Ivashkiv Arthritis research & therapy 12, 1-9, 2010 | 127 | 2010 |
Modulation of TNF-induced macrophage polarization by synovial fibroblasts LT Donlin, A Jayatilleke, EG Giannopoulou, GD Kalliolias, LB Ivashkiv The Journal of Immunology 193 (5), 2373-2383, 2014 | 119 | 2014 |
Anakinra treatment in patients with adult-onset Still’s disease is fast, effective, safe and steroid sparing: experience from an uncontrolled trial GD Kalliolias, PE Georgiou, IA Antonopoulos, AP Andonopoulos, ... Annals of the Rheumatic Diseases 66 (6), 842-843, 2007 | 118 | 2007 |
Interleukin‐27 inhibits human osteoclastogenesis by abrogating RANKL‐mediated induction of nuclear factor of activated T cells c1 and suppressing proximal RANK signaling GD Kalliolias, B Zhao, A Triantafyllopoulou, KH Park‐Min, LB Ivashkiv Arthritis & Rheumatism: Official Journal of the American College of …, 2010 | 102 | 2010 |
Suppression of TNF-α and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27 GD Kalliolias, RA Gordon, LB Ivashkiv The Journal of Immunology 185 (11), 7047-7056, 2010 | 90 | 2010 |
TNF-induced inflammatory genes escape repression in fibroblast-like synoviocytes: transcriptomic and epigenomic analysis C Loh, S Park, A Lee, R Yuan, LB Ivashkiv, GD Kalliolias Annals of the rheumatic diseases 78 (9), 1205-1214, 2019 | 83 | 2019 |
Pharmacogenetic principles in the Hippocratic writings GP Sykiotis, GD Kalliolias, AG Papavassiliou The Journal of Clinical Pharmacology 45 (11), 1218-1220, 2005 | 81 | 2005 |
Prolonged tumor necrosis factor α primes fibroblast‐like synoviocytes in a gene‐specific manner by altering chromatin C Sohn, A Lee, Y Qiao, K Loupasakis, LB Ivashkiv, GD Kalliolias Arthritis & Rheumatology 67 (1), 86-95, 2015 | 79 | 2015 |
The interferon signature and STAT1 expression in rheumatoid arthritis synovial fluid macrophages are induced by tumor necrosis factor α and counter‐regulated by … RA Gordon, G Grigoriev, A Lee, GD Kalliolias, LB Ivashkiv Arthritis & Rheumatism 64 (10), 3119-3128, 2012 | 79 | 2012 |
Combination of intravenous pulses of cyclophosphamide and methylprednizolone in patients with systemic sclerosis and interstitial lung disease G Yiannopoulos, V Pastromas, I Antonopoulos, G Katsiberis, G Kalliolias, ... Rheumatology international 27, 357-361, 2007 | 65 | 2007 |
Kinase inhibitors: a new tool for the treatment of rheumatoid arthritis SD Chakravarty, PI Poulikakos, LB Ivashkiv, JE Salmon, GD Kalliolias Clinical Immunology 148 (1), 66-78, 2013 | 53 | 2013 |
The impact of disease activity and tumor necrosis factor-α inhibitor therapy on cytokine levels in juvenile idiopathic arthritis W HM, P N, L TJ, A A, K GD, Z YS, S F, N J, S L, Cunningham-Rundles S, ... Clin Exp Immunol., 2016 | 44 | 2016 |