| Pathological and protective roles of glia in chronic pain ED Milligan, LR Watkins Nature reviews neuroscience 10 (1), 23-36, 2009 | 1664 | 2009 |
| Glial activation: a driving force for pathological pain LR Watkins, ED Milligan, SF Maier Trends in neurosciences 24 (8), 450-455, 2001 | 1417 | 2001 |
| Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats ED Milligan, C Twining, M Chacur, J Biedenkapp, K O'Connor, S Poole, ... Journal of Neuroscience 23 (3), 1026-1040, 2003 | 856 | 2003 |
| Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation A Ledeboer, EM Sloane, ED Milligan, MG Frank, JH Mahony, SF Maier, ... Pain 115 (1-2), 71-83, 2005 | 822 | 2005 |
| Spinal cord glia: new players in pain LR Watkins, ED Milligan, SF Maier Pain 93 (3), 201-205, 2001 | 509 | 2001 |
| A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine IN Johnston, ED Milligan, J Wieseler-Frank, MG Frank, V Zapata, ... Journal of Neuroscience 24 (33), 7353-7365, 2004 | 490 | 2004 |
| Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions GM Verge, ED Milligan, SF Maier, LR Watkins, GS Naeve, AC Foster European Journal of Neuroscience 20 (5), 1150-1160, 2004 | 469 | 2004 |
| Glia as the “bad guys”: implications for improving clinical pain control and the clinical utility of opioids LR Watkins, MR Hutchinson, A Ledeboer, J Wieseler-Frank, ED Milligan, ... Brain, behavior, and immunity 21 (2), 131-146, 2007 | 446 | 2007 |
| Glial proinflammatory cytokines mediate exaggerated pain states: implications for clinical pain. LR Watkins, ED Milligan, SF Maier Advances in experimental medicine and biology 521, 1-21, 2003 | 441 | 2003 |
| Intrathecal HIV-1 envelope glycoprotein gp120 induces enhanced pain states mediated by spinal cord proinflammatory cytokines ED Milligan, KA O'Connor, KT Nguyen, CB Armstrong, C Twining, ... Journal of Neuroscience 21 (8), 2808-2819, 2001 | 410 | 2001 |
| A new model of sciatic inflammatory neuritis (SIN): induction of unilateral and bilateral mechanical allodynia following acute unilateral peri-sciatic immune activation in rats M Chacur, ED Milligan, LS Gazda, C Armstrong, H Wang, KJ Tracey, ... Pain 94 (3), 231-244, 2001 | 388 | 2001 |
| Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats A Ledeboer, BM Jekich, EM Sloane, JH Mahoney, SJ Langer, ED Milligan, ... Brain, behavior, and immunity 21 (5), 686-698, 2007 | 352 | 2007 |
| Evidence that exogenous and endogenous fractalkine can induce spinal nociceptive facilitation in rats ED Milligan, V Zapata, M Chacur, D Schoeniger, J Biedenkapp, ... European Journal of Neuroscience 20 (9), 2294-2302, 2004 | 345 | 2004 |
| Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120 ED Milligan, KK Mehmert, JL Hinde, LO Harvey Jr, D Martin, KJ Tracey, ... Brain research 861 (1), 105-116, 2000 | 328 | 2000 |
| Controlling pathological pain by adenovirally driven spinal production of the anti‐inflammatory cytokine, interleukin‐10 ED Milligan, SJ Langer, EM Sloane, L He, J Wieseler‐Frank, K O'Connor, ... European Journal of Neuroscience 21 (8), 2136-2148, 2005 | 265 | 2005 |
| Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10 ED Milligan, EM Sloane, SJ Langer, PE Cruz, M Chacur, L Spataro, ... Molecular pain 1, 1744-8069-1-9, 2005 | 234 | 2005 |
| “Listening” and “talking” to neurons: implications of immune activation for pain control and increasing the efficacy of opioids LR Watkins, MR Hutchinson, ED Milligan, SF Maier Brain research reviews 56 (1), 148-169, 2007 | 233 | 2007 |
| An initial investigation of spinal mechanisms underlying pain enhancement induced by fractalkine, a neuronally released chemokine E Milligan, V Zapata, D Schoeniger, M Chacur, P Green, S Poole, ... European journal of neuroscience 22 (11), 2775-2782, 2005 | 215 | 2005 |
| Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain ED Milligan, EM Sloane, SJ Langer, TS Hughes, BM Jekich, MG Frank, ... Pain 126 (1-3), 294-308, 2006 | 198 | 2006 |
| Spinal gap junctions: potential involvement in pain facilitation LE Spataro, EM Sloane, ED Milligan, J Wieseler-Frank, D Schoeniger, ... The Journal of Pain 5 (7), 392-405, 2004 | 191 | 2004 |
