Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis K Pethe, P Bifani, J Jang, S Kang, S Park, S Ahn, J Jiricek, J Jung, ... Nature medicine 19 (9), 1157-1160, 2013 | 609 | 2013 |
The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis SPS Rao, S Alonso, L Rand, T Dick, K Pethe Proceedings of the National Academy of Sciences 105 (33), 11945-11950, 2008 | 601 | 2008 |
The heparin-binding haemagglutinin of M. tuberculosis is required for extrapulmonary dissemination K Pethe, S Alonso, F Biet, G Delogu, MJ Brennan, C Locht, FD Menozzi Nature 412 (6843), 190-194, 2001 | 566 | 2001 |
Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by autophagy S Alonso, K Pethe, DG Russell, GE Purdy Proceedings of the National Academy of Sciences 104 (14), 6031-6036, 2007 | 418 | 2007 |
Isolation of Mycobacterium tuberculosis mutants defective in the arrest of phagosome maturation K Pethe, DL Swenson, S Alonso, J Anderson, C Wang, DG Russell Proceedings of the National Academy of Sciences 101 (37), 13642-13647, 2004 | 399 | 2004 |
Identification of neutralizing linear epitopes from the VP1 capsid protein of Enterovirus 71 using synthetic peptides DGW Foo, S Alonso, MC Phoon, NP Ramachandran, VTK Chow, CL Poh Virus research 125 (1), 61-68, 2007 | 306 | 2007 |
The structural basis for serotype-specific neutralization of dengue virus by a human antibody EP Teoh, P Kukkaro, EW Teo, APC Lim, TT Tan, A Yip, W Schul, M Aung, ... Science translational medicine 4 (139), 139ra83-139ra83, 2012 | 253 | 2012 |
Methylation-dependent T cell immunity to Mycobacterium tuberculosis heparin-binding hemagglutinin S Temmerman, K Pethe, M Parra, S Alonso, C Rouanet, T Pickett, ... Nature medicine 10 (9), 935-941, 2004 | 191 | 2004 |
Passive protection against lethal enterovirus 71 infection in newborn mice by neutralizing antibodies elicited by a synthetic peptide DGW Foo, S Alonso, VTK Chow, CL Poh Microbes and infection 9 (11), 1299-1306, 2007 | 188 | 2007 |
Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection NP Kalia, EJ Hasenoehrl, NB Ab Rahman, VH Koh, MLT Ang, DR Sajorda, ... Proceedings of the National Academy of Sciences 114 (28), 7426-7431, 2017 | 186 | 2017 |
A non-mouse-adapted enterovirus 71 (EV71) strain exhibits neurotropism, causing neurological manifestations in a novel mouse model of EV71 infection WX Khong, B Yan, H Yeo, EL Tan, JJ Lee, JKW Ng, VT Chow, S Alonso Journal of virology 86 (4), 2121-2131, 2012 | 185 | 2012 |
A non mouse-adapted dengue virus strain as a new model of severe dengue infection in AG129 mice GK Tan, JKW Ng, SL Trasti, W Schul, G Yip, S Alonso PLoS neglected tropical diseases 4 (4), e672, 2010 | 183 | 2010 |
Sustained high levels of interleukin-6 contribute to the pathogenesis of enterovirus 71 in a neonate mouse model WX Khong, DGW Foo, SL Trasti, EL Tan, S Alonso Journal of virology 85 (7), 3067-3076, 2011 | 161 | 2011 |
tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence YH Chionh, M McBee, IR Babu, F Hia, W Lin, W Zhao, J Cao, ... Nature communications 7 (1), 13302, 2016 | 152 | 2016 |
Role of adhesin release for mucosal colonization by a bacterial pathogen L Coutte, S Alonso, N Reveneau, E Willery, B Quatannens, C Locht, ... The Journal of experimental medicine 197 (6), 735-742, 2003 | 150 | 2003 |
Upconversion nanoparticles for sensitive and in-depth detection of Cu 2+ ions C Li, J Liu, S Alonso, F Li, Y Zhang Nanoscale 4 (19), 6065-6071, 2012 | 143 | 2012 |
Structure-guided design of an anti-dengue antibody directed to a non-immunodominant epitope LN Robinson, K Tharakaraman, KJ Rowley, VV Costa, KR Chan, ... Cell 162 (3), 493-504, 2015 | 139 | 2015 |
Mitochondria-mediated oxidative stress during viral infection J Foo, G Bellot, S Pervaiz, S Alonso Trends in Microbiology 30 (7), 679-692, 2022 | 135 | 2022 |
Glutathione deficiency in type 2 diabetes impairs cytokine responses and control of intracellular bacteria KS Tan, KO Lee, KC Low, AM Gamage, Y Liu, GYG Tan, HQV Koh, ... The Journal of clinical investigation 122 (6), 2289-2300, 2012 | 124 | 2012 |
First Experimental In Vivo Model of Enhanced Dengue Disease Severity through Maternally Acquired Heterotypic Dengue Antibodies JKW Ng, SL Zhang, HC Tan, B Yan, J Maria Martinez Gomez, WY Tan, ... PLoS pathogens 10 (4), e1004031, 2014 | 119 | 2014 |