Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD K Mizumura, SM Cloonan, K Nakahira, AR Bhashyam, M Cervo, T Kitada, ... The Journal of clinical investigation 124 (9), 3987-4003, 2014 | 556 | 2014 |
Understanding tissue-specific gene regulation AR Sonawane, J Platig, M Fagny, CY Chen, JN Paulson, ... Cell reports 21 (4), 1077-1088, 2017 | 384 | 2017 |
CpG methylation of half-CRE sequences creates C/EBPα binding sites that activate some tissue-specific genes V Rishi, P Bhattacharya, R Chatterjee, J Rozenberg, J Zhao, K Glass, ... Proceedings of the National Academy of Sciences 107 (47), 20311-20316, 2010 | 264 | 2010 |
Sex differences in gene expression and regulatory networks across 29 human tissues CM Lopes-Ramos, CY Chen, ML Kuijjer, JN Paulson, AR Sonawane, ... Cell reports 31 (12), 2020 | 247 | 2020 |
KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors JC Black, AL Manning, C Van Rechem, J Kim, B Ladd, J Cho, CM Pineda, ... Cell 154 (3), 541-555, 2013 | 245 | 2013 |
Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis J Xu, Z Shao, K Glass, DE Bauer, L Pinello, B Van Handel, S Hou, ... Developmental cell 23 (4), 796-811, 2012 | 233 | 2012 |
Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice SM Cloonan, K Glass, ME Laucho-Contreras, AR Bhashyam, M Cervo, ... Nature medicine 22 (2), 163-174, 2016 | 225 | 2016 |
Passing messages between biological networks to refine predicted interactions K Glass, C Huttenhower, J Quackenbush, GC Yuan PloS one 8 (5), e64832, 2013 | 203 | 2013 |
ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients E Baena, Z Shao, DE Linn, K Glass, MJ Hamblen, Y Fujiwara, J Kim, ... Genes & development 27 (6), 683-698, 2013 | 202 | 2013 |
Molecular networks in Network Medicine: Development and applications EK Silverman, HHHW Schmidt, E Anastasiadou, L Altucci, M Angelini, ... Wiley Interdisciplinary Reviews: Systems Biology and Medicine 12 (6), e1489, 2020 | 172 | 2020 |
Network medicine in the age of biomedical big data AR Sonawane, ST Weiss, K Glass, A Sharma Frontiers in Genetics 10, 445334, 2019 | 170 | 2019 |
Developmental control of polycomb subunit composition by GATA factors mediates a switch to non-canonical functions J Xu, Z Shao, D Li, H Xie, W Kim, J Huang, JE Taylor, L Pinello, K Glass, ... Molecular cell 57 (2), 304-316, 2015 | 150 | 2015 |
Estimating sample-specific regulatory networks ML Kuijjer, M Tung, GC Yuan, J Quackenbush, K Glass Available at SSRN 3253573, 2018 | 133 | 2018 |
Gene Regulatory Network Analysis Identifies Sex-Linked Differences in Colon Cancer Drug Metabolism CM Lopes-Ramos, ML Kuijjer, S Ogino, CS Fuchs, DL DeMeo, K Glass, ... Cancer research 78 (19), 5538-5547, 2018 | 100 | 2018 |
Exploring regulation in tissues with eQTL networks M Fagny, JN Paulson, ML Kuijjer, AR Sonawane, CY Chen, ... Proceedings of the National Academy of Sciences 114 (37), E7841-E7850, 2017 | 97 | 2017 |
Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue JD Morrow, X Zhou, T Lao, Z Jiang, DL DeMeo, MH Cho, W Qiu, ... Scientific reports 7, 44232, 2017 | 91 | 2017 |
DNA methylation profiling in human lung tissue identifies genes associated with COPD JD Morrow, MH Cho, CP Hersh, V Pinto-Plata, B Celli, N Marchetti, ... Epigenetics 11 (10), 730-739, 2016 | 90 | 2016 |
All and only CpG containing sequences are enriched in promoters abundantly bound by RNA polymerase II in multiple tissues JM Rozenberg, A Shlyakhtenko, K Glass, V Rishi, MV Myakishev, ... BMC genomics 9, 1-13, 2008 | 82 | 2008 |
Robustness and lethality in multilayer biological molecular networks X Liu, E Maiorino, A Halu, K Glass, RB Prasad, J Loscalzo, J Gao, ... Nature communications 11 (1), 6043, 2020 | 79 | 2020 |
Annotation enrichment analysis: an alternative method for evaluating the functional properties of gene sets K Glass, M Girvan Scientific reports 4, 2014 | 75 | 2014 |