Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4 J Nichols, B Zevnik, K Anastassiadis, H Niwa, D Klewe-Nebenius, ... Cell 95 (3), 379-391, 1998 | 4370 | 1998 |
Expression pattern of Oct-4 in preimplantation embryos of different species N Kirchhof, JW Carnwath, E Lemme, K Anastassiadis, H Scholer, ... Biology of reproduction 63 (6), 1698-1705, 2000 | 436 | 2000 |
New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2 V Botquin, H Hess, G Fuhrmann, C Anastassiadis, MK Gross, G Vriend, ... Genes & development 12 (13), 2073-2090, 1998 | 408 | 1998 |
A mouse model for hereditary thyroid dysgenesis and cleft palate M De Felice, C Ovitt, E Biffali, A Rodriguez-Mallon, C Arra, ... Nature genetics 19 (4), 395-398, 1998 | 404 | 1998 |
A localized Wnt signal orients asymmetric stem cell division in vitro SJ Habib, BC Chen, FC Tsai, K Anastassiadis, T Meyer, E Betzig, ... Science 339 (6126), 1445-1448, 2013 | 360 | 2013 |
Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice K Anastassiadis, J Fu, C Patsch, S Hu, S Weidlich, K Duerschke, ... Disease models & mechanisms 2 (9-10), 508-515, 2009 | 331 | 2009 |
Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development S Glaser, J Schaft, S Lubitz, K Vintersten, F van der Hoeven, KR Tufteland, ... Oxford University Press for The Company of Biologists Limited 133 (8), 1423-1432, 2006 | 331 | 2006 |
The mammalian gene function resource: the International Knockout Mouse Consortium A Bradley, K Anastassiadis, A Ayadi, JF Battey, C Bell, MC Birling, ... Mammalian genome 23, 580-586, 2012 | 324 | 2012 |
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity L Ding, M Paszkowski-Rogacz, A Nitzsche, MM Slabicki, AK Heninger, ... Cell stem cell 4 (5), 403-415, 2009 | 309 | 2009 |
A short G1 phase is an intrinsic determinant of naive embryonic stem cell pluripotency D Coronado, M Godet, PY Bourillot, Y Tapponnier, A Bernat, M Petit, ... Stem cell research 10 (1), 118-131, 2013 | 302 | 2013 |
Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant S Denissov, H Hofemeister, H Marks, A Kranz, G Ciotta, S Singh, ... Development 141 (3), 526-537, 2014 | 283 | 2014 |
Retinal organoids from pluripotent stem cells efficiently recapitulate retinogenesis M Völkner, M Zschätzsch, M Rostovskaya, RW Overall, V Busskamp, ... Stem cell reports 6 (4), 525-538, 2016 | 281 | 2016 |
Targeted Mutation Reveals Essential Functions of the Homeodomain Transcription Factor Shox2 in Sinoatrial and Pacemaking Development RJ Blaschke, ND Hahurij, S Kuijper, S Just, LJ Wisse, K Deissler, ... Circulation 115 (14), 1830-1838, 2007 | 279 | 2007 |
MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing CV Andreu-Vieyra, R Chen, JE Agno, S Glaser, K Anastassiadis, ... PLoS biology 8 (8), e1000453, 2010 | 273 | 2010 |
Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1 K Daniel, J Lange, K Hached, J Fu, K Anastassiadis, I Roig, HJ Cooke, ... Nature cell biology 13 (5), 599-610, 2011 | 245 | 2011 |
Tightly anchored tissue-mimetic matrices as instructive stem cell microenvironments MC Prewitz, FP Seib, M Von Bonin, J Friedrichs, A Stißel, C Niehage, ... Nature methods 10 (8), 788-794, 2013 | 238 | 2013 |
A reliable lacZ expression reporter cassette for multipurpose, knockout‐first alleles G Testa, J Schaft, F Van Der Hoeven, S Glaser, K Anastassiadis, Y Zhang, ... genesis 38 (3), 151-158, 2004 | 233 | 2004 |
Current issues in mouse genome engineering S Glaser, K Anastassiadis, AF Stewart Nature genetics 37 (11), 1187-1193, 2005 | 231 | 2005 |
The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis S Glaser, S Lubitz, KL Loveland, K Ohbo, L Robb, F Schwenk, J Seibler, ... Epigenetics & chromatin 2, 1-16, 2009 | 193 | 2009 |
The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation AS Bledau, K Schmidt, K Neumann, U Hill, G Ciotta, A Gupta, DC Torres, ... Development 141 (5), 1022-1035, 2014 | 191 | 2014 |