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| Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation AS Nam, N Dusaj, F Izzo, R Murali, RM Myers, TH Mouhieddine, J Sotelo, ... Nature genetics 54 (10), 1514-1526, 2022 | 81 | 2022 |
| Splicing factor mutations in hematologic malignancies S Chen, S Benbarche, O Abdel-Wahab Blood, The Journal of the American Society of Hematology 138 (8), 599-612, 2021 | 63 | 2021 |
| Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms J Taylor, X Mi, K North, M Binder, A Penson, T Lasho, K Knorr, ... Blood, The Journal of the American Society of Hematology 136 (13), 1477-1486, 2020 | 53 | 2020 |
| Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells K North, S Benbarche, B Liu, J Pangallo, S Chen, M Stahl, JP Bewersdorf, ... Nature biotechnology 40 (7), 1103-1113, 2022 | 44 | 2022 |
| Impaired proteolysis of noncanonical RAS proteins drives clonal hematopoietic transformation S Chen, RS Vedula, A Cuevas-Navarro, B Lu, SJ Hogg, E Wang, ... Cancer discovery 12 (10), 2434-2453, 2022 | 17 | 2022 |
| Dual role of IL-21 in megakaryopoiesis and platelet homeostasis S Benbarche, C Strassel, C Angénieux, L Mallo, M Freund, C Gachet, ... haematologica 102 (4), 637, 2017 | 16 | 2017 |
| Screening of ETO2-GLIS2–induced Super Enhancers identifies targetable cooperative dependencies in acute megakaryoblastic leukemia S Benbarche, CK Lopez, E Salataj, Z Aid, C Thirant, MC Laiguillon, ... Science advances 8 (6), eabg9455, 2022 | 13 | 2022 |
| High caspase 3 and vulnerability to dual BCL2 family inhibition define ETO2:: GLIS2 pediatric leukemia Z Aid, E Robert, CK Lopez, M Bourgoin, F Boudia, M Le Mene, J Riviere, ... Leukemia 37 (3), 571-579, 2023 | 7 | 2023 |
| GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies S Benbarche, JMB Pineda, LB Galvis, J Biswas, B Liu, E Wang, Q Zhang, ... Molecular Cell 84 (10), 1886-1903. e10, 2024 | 5 | 2024 |
| Harnessing introns to monitor gene expression S Benbarche, O Abdel-Wahab Nature cell biology 24 (11), 1571-1573, 2022 | 1 | 2022 |
| Single-Cell Multi-Omics in Human Clonal Hematopoiesis Reveals That DNMT3A R882 Mutations Perturb Early Progenitor States through Selective Hypomethylation AS Nam, N Dusaj, F Izzo, R Murali, TH Mouhieddine, RM Myers, J Sotelo, ... Blood 136, 1-2, 2020 | 1 | 2020 |
| PitViper: a software for comparative meta-analysis and annotation of functional screening data PA Meslin, LM Kelly, S Benbarche, S Lecourt, KH Lin, JC Rutter, ... NAR Genomics and Bioinformatics 6 (2), lqae059, 2024 | | 2024 |
| Synthetic introns for targeted gene expression RK Bradley, O Abdel-Wahab, K North, S Benbarche, B Liu US Patent App. 18/249,914, 2024 | | 2024 |
| Genome-Wide Mapping of R-Loops in Single Cells Reveals Cell-Type Specific Roles for R-Loops in Hematopoietic Cell Identity B Lu, P Zhang, S Chen, S Benbarche, C Castro, N Fox, M Abubakar, ... Blood 142, 242, 2023 | | 2023 |
| Synthetic Introns Identify the Novel RNA Splicing Factor GPATCH8 As Required for Mis-Splicing Induced By SF3B1 Mutations S Benbarche, JMB Pineda, LB Galvis, B Liu, J Biswas, E Wang, KA Lyttle, ... Blood 142, 3, 2023 | | 2023 |
| RAF-Independent MEK Mutations Drive Histiocytic Neoplasms In Vivo and Are Sensitive to Single-Agent ERK Inhibition in Patients BH Durham, ME Singer, S Benbarche, C Erickson, J Rahman, DB Solit, ... Blood 140 (Supplement 1), 1098-1100, 2022 | | 2022 |
| Impaired RAS Proteolysis Drives Clonal Hematopoietic Transformation S Chen, RS Vedula, P Castel, AC Navarro, SJ Hogg, E Wang, X Mi, ... Blood 138, 356, 2021 | | 2021 |
| SINGLE-CELL GENOMICS REVEALS THE GENETIC AND MOLECULAR BASES FOR ESCAPE FROM MUTATIONAL EPISTASIS IN MYELOID NEOPLASMS M Binder, A Penson, T Lasho, K Knorr, M Haddadin, B Liu, J Pangallo, ... Mechanistic consequences of splicing factor mutations and their use for …, 2020 | | 2020 |
| Dual role of IL-21 in megakaryopoiesis and platelet homeostasis: Modulation of platelet homeostasis by IL-21 S Benbarche, C Strassel, C Angénieux, L Mallo, M Freund, C Gachet, ... < bound method Organization. get_name_with_acronym of< Organization: Inserm …, 2017 | | 2017 |
