Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer … KRA Abdellatif, WAA Fadaly, YA Mostafa, DM Zaher, HA Omar Bioorganic Chemistry 91, 103132, 2019 | 50 | 2019 |
Synthesis and antimicrobial activity of certain new 1, 2, 4-triazolo [1, 5-a] pyrimidine derivatives YAH Mostafa, MA Hussein, AA Radwan, AEHN Kfafy Archives of pharmacal research 31, 279-293, 2008 | 42 | 2008 |
Steroid derivatives as inhibitors of steroid sulfatase YAM Abdel-Karem Journal of Steroid Biochemistry & Molecular Biology 137, 183– 198, 2013 | 40* | 2013 |
Inhibition of steroid sulfatase with 4-substituted estrone and estradiol derivatives CM Phan, Y Liu, B Kim, Y Mostafa, SD Taylor Bioorganic & medicinal chemistry 19 (20), 5999-6005, 2011 | 37 | 2011 |
Discovery of new pyrimido [5, 4-c] quinolines as potential antiproliferative agents with multitarget actions: Rapid synthesis, docking, and ADME studies RA Mekheimer, SMR Allam, MA Al-Sheikh, MS Moustafa, SM Al-Mousawi, ... Bioorganic Chemistry 121, 105693, 2022 | 33 | 2022 |
Antioxidant and Wound Healing Potential of Vitis vinifera Seeds Supported by Phytochemical Characterization and Docking Studies T Al-Warhi, EM Zahran, S Selim, MM Al-Sanea, MM Ghoneim, SA Maher, ... Antioxidants 11 (5), 881, 2022 | 31 | 2022 |
A first-in-class anticancer dual HDAC2/FAK inhibitors bearing hydroxamates/benzamides capped by pyridinyl-1, 2, 4-triazoles M Mustafa, AA Abd El-Hafeez, D Abdelhamid, GD Katkar, YA Mostafa, ... European journal of medicinal chemistry 222, 113569, 2021 | 26 | 2021 |
17β-Arylsulfonamides of 17β-aminoestra-1, 3, 5 (10)-trien-3-ol as highly potent inhibitors of steroid sulfatase YA Mostafa, SD Taylor Bioorganic & medicinal chemistry 20 (4), 1535-1544, 2012 | 24 | 2012 |
A facile synthesis, drug-likeness, and in silico molecular docking of certain new azidosulfonamide–chalcones and their in vitro antimicrobial activity M Mustafa, YA Mostafa Monatshefte für Chemie-Chemical Monthly 151, 417-427, 2020 | 21 | 2020 |
Novel piperine-carboximidamide hybrids: Design, synthesis, and antiproliferative activity via a multi-targeted inhibitory pathway LH Al-Wahaibi, MA Mahmoud, YA Mostafa, AE Raslan, BGM Youssif Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 376-386, 2023 | 19 | 2023 |
Wound Healing and Antioxidant Capabilities of Zizyphus mauritiana Fruits: In-Vitro, In-Vivo, and Molecular Modeling Study NH Shady, R Soltane, SA Maher, EA Saber, MA Elrehany, YA Mostafa, ... Plants 11 (11), 1392, 2022 | 19 | 2022 |
Antimicrobial pyridazines: synthesis, characterization, cytotoxicity, substrate promiscuity, and molecular docking M Mustafa, YA Mostafa Chemistry & Biodiversity 17 (6), e2000100, 2020 | 19 | 2020 |
Synthesis and biological evaluation of indole-2-carboxamides with potent apoptotic antiproliferative activity as egfr/cdk2 dual inhibitors LH Al-Wahaibi, YA Mostafa, MH Abdelrahman, AH El-Bahrawy, ... Pharmaceuticals 15 (8), 1006, 2022 | 18 | 2022 |
Novel urea linked ciprofloxacin-chalcone hybrids having antiproliferative topoisomerases I/II inhibitory activities and caspases-mediated apoptosis HHH Mohammed, SH Abbas, AM Hayallah, GEDA Abuo-Rahma, ... Bioorganic Chemistry 106, 104422, 2021 | 18 | 2021 |
Novel 1, 5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects OM Hendawy, HAM Gomaa, SI Alzarea, MS Alshammari, FAM Mohamed, ... Bioorganic Chemistry 116, 105302, 2021 | 16 | 2021 |
FAK inhibitors as promising anticancer targets: present and future directions M Mustafa, AA Abd El-Hafeez, DA Abdelhafeez, D Abdelhamid, ... Future medicinal chemistry 13 (18), 1559-1590, 2021 | 15 | 2021 |
A-ring substituted 17β-arylsulfonamides of 17β-aminoestra-1, 3, 5 (10)-trien-3-ol as highly potent reversible inhibitors of steroid sulfatase YA Mostafa, B Kralt, PPN Rao, SD Taylor Bioorganic & Medicinal Chemistry 23 (17), 5681-5692, 2015 | 14 | 2015 |
Discovery of novel oxazole-based macrocycles as anti-coronaviral agents targeting SARS-CoV-2 main protease LH Al-Wahaibi, A Mostafa, YA Mostafa, OF Abou-Ghadir, AH Abdelazeem, ... Bioorganic Chemistry 116, 105363, 2021 | 13 | 2021 |
Discovery of new cyanopyridine/chalcone hybrids as dual inhibitors of EGFR/BRAFV600E with promising antiproliferative properties HA Abou‐Zied, EAM Beshr, HAM Gomaa, YA Mostafa, BGM Youssif, ... Archiv der Pharmazie 356 (4), 2200464, 2023 | 12 | 2023 |
Novel indazole derivatives as potent apoptotic antiproliferative agents by multi-targeted mechanism: Synthesis and biological evaluation FOA Frejat, H Zhai, Y Cao, L Wang, YA Mostafa, HAM Gomaa, ... Bioorganic Chemistry 126, 105922, 2022 | 10 | 2022 |