Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome MA Lanaspa, T Ishimoto, N Li, C Cicerchi, DJ Orlicky, P Ruzycki, C Rivard, ... Nature communications 4 (1), 2434, 2013 | 251 | 2013 |
High-molecular-weight aggregates in repackaged bevacizumab MY Kahook, L Liu, P Ruzycki, N Mandava, JF Carpenter, JM Petrash, ... Retina 30 (6), 887-892, 2010 | 164 | 2010 |
Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease TA Ray, K Cochran, C Kozlowski, J Wang, G Alexander, MA Cady, ... Nature communications 11 (1), 3328, 2020 | 94 | 2020 |
Aldose reductase expression as a risk factor for cataract A Snow, B Shieh, KC Chang, A Pal, P Lenhart, D Ammar, P Ruzycki, ... Chemico-biological interactions 234, 247-253, 2015 | 77 | 2015 |
Aldose reductase-mediated induction of epithelium-to-mesenchymal transition (EMT) in lens GJ Zablocki, PA Ruzycki, MA Overturf, S Palla, GB Reddy, JM Petrash Chemico-biological interactions 191 (1-3), 351-356, 2011 | 52 | 2011 |
Atoh7-independent specification of retinal ganglion cell identity J Brodie-Kommit, BS Clark, Q Shi, F Shiau, DW Kim, J Langel, C Sheely, ... Science advances 7 (11), eabe4983, 2021 | 48 | 2021 |
Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies PA Ruzycki, NM Tran, AV Kolesnikov, VJ Kefalov, S Chen Genome biology 16, 1-22, 2015 | 45 | 2015 |
Aldo‐keto reductases in the eye SP Huang, S Palla, P Ruzycki, RA Varma, T Harter, GB Reddy, ... Journal of ophthalmology 2010 (1), 521204, 2010 | 41 | 2010 |
CRX directs photoreceptor differentiation by accelerating chromatin remodeling at specific target sites PA Ruzycki, X Zhang, S Chen Epigenetics & Chromatin 11, 1-16, 2018 | 35 | 2018 |
A single-cell guide to retinal development: Cell fate decisions of multipotent retinal progenitors in scRNA-seq F Shiau, PA Ruzycki, BS Clark Developmental biology 478, 41-58, 2021 | 28 | 2021 |
Multiple isoforms of nesprin1 are integral components of ciliary rootlets C Potter, W Zhu, D Razafsky, P Ruzycki, AV Kolesnikov, T Doggett, ... Current Biology 27 (13), 2014-2022. e6, 2017 | 28 | 2017 |
AMIGO2 scales dendrite arbors in the retina F Soto, NW Tien, A Goel, L Zhao, PA Ruzycki, D Kerschensteiner Cell reports 29 (6), 1568-1578. e4, 2019 | 19 | 2019 |
Dry eye disease in mice activates adaptive corneal epithelial regeneration distinct from constitutive renewal in homeostasis JB Lin, X Shen, CW Pfeifer, F Shiau, A Santeford, PA Ruzycki, BS Clark, ... Proceedings of the National Academy of Sciences 120 (2), e2204134120, 2023 | 14 | 2023 |
MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity DS Brightman, RL Grant, PA Ruzycki, R Suzuki, AK Hennig, S Chen Scientific reports 8 (1), 11902, 2018 | 14 | 2018 |
Mutation of the EPHA2 tyrosine-kinase domain dysregulates cell pattern formation and cytoskeletal gene expression in the lens Y Zhou, TM Bennett, PA Ruzycki, A Shiels Cells 10 (10), 2606, 2021 | 12 | 2021 |
Clinicomolecular identification of conserved and individualized features of granulomatous uveitis LM Hassman, MA Paley, E Esaulova, GL Paley, PA Ruzycki, N Linskey, ... Ophthalmology science 1 (1), 100010, 2021 | 11 | 2021 |
Loss of Mir146b with aging contributes to inflammation and mitochondrial dysfunction in thioglycollate-elicited peritoneal macrophages A Santeford, AY Lee, A Sene, LM Hassman, AA Sergushichev, ... Elife 10, e66703, 2021 | 8 | 2021 |
Dysregulated CD200-CD200R signaling in early diabetes modulates microglia-mediated retinopathy CW Pfeifer, JT Walsh, A Santeford, JB Lin, WL Beatty, R Terao, YA Liu, ... Proceedings of the National Academy of Sciences 120 (45), e2308214120, 2023 | 5 | 2023 |
Missense mutations in CRX homeodomain cause dominant retinopathies through two distinct mechanisms Y Zheng, C Sun, X Zhang, PA Ruzycki, S Chen Elife 12, RP87147, 2023 | 4 | 2023 |
A cataract-causing mutation in the TRPM3 cation channel disrupts calcium dynamics in the lens Y Zhou, TM Bennett, PA Ruzycki, Z Guo, YQ Cao, M Shahidullah, ... Cells 13 (3), 257, 2024 | 2 | 2024 |