| Identification of neutral tumor evolution across cancer types MJ Williams, B Werner, CP Barnes, TA Graham, A Sottoriva Nature genetics 48 (3), 238-244, 2016 | 654 | 2016 |
| Quantification of subclonal selection in cancer from bulk sequencing data MJ Williams, B Werner, T Heide, C Curtis, CP Barnes, A Sottoriva, ... Nature genetics 50 (6), 895-903, 2018 | 242 | 2018 |
| Longitudinal liquid biopsy and mathematical modeling of clonal evolution forecast time to treatment failure in the PROSPECT-C phase II colorectal cancer clinical trial KH Khan, D Cunningham, B Werner, G Vlachogiannis, I Spiteri, T Heide, ... Cancer discovery 8 (10), 1270-1285, 2018 | 214 | 2018 |
| Subclonal reconstruction of tumors by using machine learning and population genetics G Caravagna, T Heide, MJ Williams, L Zapata, D Nichol, K Chkhaidze, ... Nature genetics 52 (9), 898-907, 2020 | 95 | 2020 |
| Exploiting evolutionary steering to induce collateral drug sensitivity in cancer A Acar, D Nichol, J Fernandez-Mateos, GD Cresswell, I Barozzi, SP Hong, ... Nature communications 11 (1), 1923, 2020 | 94 | 2020 |
| Evolutionary dynamics of neoantigens in growing tumors E Lakatos, MJ Williams, RO Schenck, WCH Cross, J Househam, L Zapata, ... Nature genetics 52 (10), 1057-1066, 2020 | 92 | 2020 |
| Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions B Werner, F Beier, S Hummel, S Balabanov, L Lassay, T Orlikowsky, ... eLife, e08687v2, 2015 | 85 | 2015 |
| Phenotypic plasticity and genetic control in colorectal cancer evolution J Househam, T Heide, GD Cresswell, I Spiteri, C Kimberley, L Zapata, ... Nature 611 (7937), 744-753, 2022 | 84 | 2022 |
| Dynamics of mutant cells in hierarchical organized tissues B Werner, D Dingli, T Lenaerts, JM Pacheco, A Traulsen PLoS computational biology 7 (12), e1002290, 2011 | 74 | 2011 |
| Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data K Chkhaidze, T Heide, B Werner, MJ Williams, W Huang, G Caravagna, ... PLoS computational biology 15 (7), e1007243, 2019 | 71 | 2019 |
| Evolutionary dynamics of residual disease in human glioblastoma I Spiteri, G Caravagna, GD Cresswell, A Vatsiou, D Nichol, A Acar, ... Annals of Oncology 30 (3), 456-463, 2019 | 68 | 2019 |
| The cancer stem cell fraction in hierarchically organized tumors can be estimated using mathematical modeling and patient-specific treatment trajectories B Werner, JG Scott, A Sottoriva, ARA Anderson, A Traulsen, PM Altrock Cancer research 76 (7), 1705-1713, 2016 | 66 | 2016 |
| The evolutionary dynamics of extrachromosomal DNA in human cancers JT Lange, JC Rose, CY Chen, Y Pichugin, L Xie, J Tang, KL Hung, ... Nature genetics 54 (10), 1527-1533, 2022 | 63 | 2022 |
| Measuring single cell divisions in human tissues from multi-region sequencing data B Werner, J Case, MJ Williams, K Chkhaidze, D Temko, ... Nature communications 11 (1), 1035, 2020 | 62 | 2020 |
| A deterministic model for the occurrence and dynamics of multiple mutations in hierarchically organized tissues B Werner, D Dingli, A Traulsen Journal of The Royal Society Interface 10 (85), 20130349, 2013 | 53 | 2013 |
| Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios MJ Williams, L Zapata, B Werner, CP Barnes, A Sottoriva, TA Graham Elife 9, e48714, 2020 | 38 | 2020 |
| Dynamics of leukemia stem-like cell extinction in acute promyelocytic leukemia B Werner, RE Gallagher, EM Paietta, MR Litzow, MS Tallman, PH Wiernik, ... Cancer research 74 (19), 5386-5396, 2014 | 37 | 2014 |
| Dynamical trade-offs arise from antagonistic coevolution and decrease intraspecific diversity W Huang, A Traulsen, B Werner, T Hiltunen, L Becks Nature Communications 8 (1), 2059, 2017 | 35 | 2017 |
| Should tissue structure suppress or amplify selection to minimize cancer risk? L Hindersin, B Werner, D Dingli, A Traulsen Biology direct 11, 1-11, 2016 | 35 | 2016 |
| Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates B Werner, A Sottoriva PLoS computational biology 14 (6), e1006233, 2018 | 33 | 2018 |
Andrea SottorivaHuman Technopole在 fht.org 的电子邮件经过验证
