| Drug delivery systems for RNA therapeutics K Paunovska, D Loughrey, JE Dahlman Nature Reviews Genetics 23 (5), 265-280, 2022 | 643 | 2022 |
| High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing CD Sago, MP Lokugamage, K Paunovska, DA Vanover, CM Monaco, ... Proceedings of the National Academy of Sciences 115 (42), E9944-E9952, 2018 | 259 | 2018 |
| A direct comparison of in vitro and in vivo nucleic acid delivery mediated by hundreds of nanoparticles reveals a weak correlation K Paunovska, CD Sago, CM Monaco, WH Hudson, MG Castro, ... Nano letters 18 (3), 2148-2157, 2018 | 186 | 2018 |
| Nanoparticles containing oxidized cholesterol deliver mRNA to the liver microenvironment at clinically relevant doses K Paunovska, AJ Da Silva Sanchez, CD Sago, Z Gan, MP Lokugamage, ... Advanced materials 31 (14), 1807748, 2019 | 160 | 2019 |
| Analyzing 2000 in Vivo Drug Delivery Data Points Reveals Cholesterol Structure Impacts Nanoparticle Delivery K Paunovska, CJ Gil, MP Lokugamage, CD Sago, M Sato, GN Lando, ... ACS nano 12 (8), 8341-8349, 2018 | 119 | 2018 |
| Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles MZC Hatit, MP Lokugamage, CN Dobrowolski, K Paunovska, H Ni, ... Nature nanotechnology 17 (3), 310-318, 2022 | 78 | 2022 |
| Using large datasets to understand nanotechnology K Paunovska, D Loughrey, CD Sago, R Langer, JE Dahlman Advanced Materials 31 (43), 1902798, 2019 | 63 | 2019 |
| Treating cystic fibrosis with mRNA and CRISPR A Da Silva Sanchez, K Paunovska, A Cristian, JE Dahlman Human gene therapy 31 (17-18), 940-955, 2020 | 54 | 2020 |
| Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery C Dobrowolski, K Paunovska, E Schrader Echeverri, D Loughrey, ... Nature Nanotechnology 17 (8), 871-879, 2022 | 53 | 2022 |
| Nanoparticles containing constrained phospholipids deliver mRNA to liver immune cells in vivo without targeting ligands Z Gan, MP Lokugamage, MZC Hatit, D Loughrey, K Paunovska, M Sato, ... Bioengineering & translational medicine 5 (3), e10161, 2020 | 49 | 2020 |
| Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver CD Sago, MP Lokugamage, D Loughrey, KE Lindsay, R Hincapie, ... Nature biomedical engineering 6 (2), 157-167, 2022 | 45 | 2022 |
| Therapeutic RNA delivery for COVID and other diseases C Dobrowolski, K Paunovska, MZC Hatit, MP Lokugamage, JE Dahlman Advanced healthcare materials 10 (15), 2002022, 2021 | 38 | 2021 |
| The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo A Radmand, MP Lokugamage, H Kim, C Dobrowolski, R Zenhausern, ... Nano letters 23 (3), 993-1002, 2023 | 30 | 2023 |
| Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery MZC Hatit, CN Dobrowolski, MP Lokugamage, D Loughrey, H Ni, C Zurla, ... Nature Chemistry 15 (4), 508-515, 2023 | 27 | 2023 |
| High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo SG Huayamares, MP Lokugamage, R Rab, AJDS Sanchez, H Kim, ... Journal of Controlled Release 357, 394-403, 2023 | 24 | 2023 |
| Substituting racemic ionizable lipids with stereopure ionizable lipids can increase mRNA delivery AJDS Sanchez, K Zhao, SG Huayamares, MZC Hatit, MP Lokugamage, ... Journal of Controlled Release 353, 270-277, 2023 | 24 | 2023 |
| Universal Barcoding Predicts In Vivo ApoE-Independent Lipid Nanoparticle Delivery AJ Da Silva Sanchez, C Dobrowolski, A Cristian, ES Echeverri, K Zhao, ... Nano Letters 22 (12), 4822-4830, 2022 | 24 | 2022 |
| Increased PIP3 activity blocks nanoparticle mRNA delivery K Paunovska, A Da Silva Sanchez, MT Foster, D Loughrey, EL Blanchard, ... Science advances 6 (30), eaba5672, 2020 | 20 | 2020 |
| Characterization of polyethylene glycol–reinforced alginate microcapsules for mechanically stable cell immunoisolation CA Verheyen, L Morales, J Sussman, K Paunovska, V Manzoli, ... Macromolecular materials and engineering 304 (4), 1800679, 2019 | 20 | 2019 |
| The extent to which lipid nanoparticles require apolipoprotein E and low-density lipoprotein receptor for delivery changes with ionizable lipid structure K Paunovska, AJ Da Silva Sanchez, MP Lokugamage, D Loughrey, ... Nano letters 22 (24), 10025-10033, 2022 | 17 | 2022 |
James E. DahlmanEmory School of Medicine / Georgia Tech在 emory.edu 的电子邮件经过验证
