Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption JR Ussher, TR Koves, VJJ Cadete, L Zhang, JS Jaswal, SJ Swyrd, ... Diabetes 59 (10), 2453-2464, 2010 | 405 | 2010 |
The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the … L Piao, YH Fang, VJJ Cadete, C Wietholt, D Urboniene, PT Toth, ... Journal of molecular medicine 88, 47-60, 2010 | 358 | 2010 |
Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation L Zhang, JR Ussher, T Oka, VJJ Cadete, C Wagg, GD Lopaschuk Cardiovascular research 89 (1), 148-156, 2011 | 152 | 2011 |
Formation of mitochondrial‐derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system VJJ Cadete, S Deschênes, A Cuillerier, F Brisebois, A Sugiura, A Vincent, ... The Journal of physiology 594 (18), 5343-5362, 2016 | 146 | 2016 |
Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy RA Carvalho, RPB Sousa, VJJ Cadete, GD Lopaschuk, CMM Palmeira, ... Toxicology 270 (2-3), 92-98, 2010 | 140 | 2010 |
Medical therapy for heart failure associated with pulmonary hypertension JGE Zelt, KR Chaudhary, VJ Cadete, LM Mielniczuk, DJ Stewart Circulation research 124 (11), 1551-1567, 2019 | 62 | 2019 |
Inhibition of serine palmitoyl transferase I reduces cardiac ceramide levels and increases glycolysis rates following diet-induced insulin resistance JR Ussher, CDL Folmes, W Keung, N Fillmore, JS Jaswal, VJ Cadete, ... PLoS One 7 (5), e37703, 2012 | 61 | 2012 |
Ischemia induced peroxynitrite dependent modifications of cardiomyocyte MLC1 increases its degradation by MMP‐2 leading to contractile dysfunction D Polewicz, VJJ Cadete, A Doroszko, BE Hunter, J Sawicka, ... Journal of cellular and molecular medicine 15 (5), 1136-1147, 2011 | 54 | 2011 |
Ischemia/reperfusion‐induced myosin light chain 1 phosphorylation increases its degradation by matrix metalloproteinase 2 VJJ Cadete, J Sawicka, JS Jaswal, GD Lopaschuk, R Schulz, ... The FEBS journal 279 (13), 2444-2454, 2012 | 52 | 2012 |
Proteomics characterization of mitochondrial‐derived vesicles under oxidative stress G Vasam, R Nadeau, VJJ Cadete, M Lavallée‐Adam, KJ Menzies, ... The FASEB Journal 35 (4), 2021 | 47 | 2021 |
Proliferative versus degenerative paradigms in pulmonary arterial hypertension: have we put the cart before the horse? KR Chaudhary, M Taha, VJJ Cadete, RS Godoy, DJ Stewart Circulation Research 120 (8), 1237-1239, 2017 | 47 | 2017 |
Loss of hepatic LRPPRC alters mitochondrial bioenergetics, regulation of permeability transition and trans-membrane ROS diffusion A Cuillerier, S Honarmand, VJJ Cadete, M Ruiz, A Forest, S Deschênes, ... Human Molecular Genetics 26 (16), 3186-3201, 2017 | 46 | 2017 |
Neonatal asphyxia induces the nitration of cardiac myosin light chain 2 that is associated with cardiac systolic dysfunction A Doroszko, D Polewicz, VJJ Cadete, J Sawicka, M Jones, ... Shock 34 (6), 592-600, 2010 | 46 | 2010 |
Differential proteomic analysis of highly purified placental cytotrophoblasts in pre‐eclampsia demonstrates a state of increased oxidative stress and reduced cytotrophoblast … ED Johnstone, G Sawicki, L Guilbert, B Winkler‐Lowen, VJJ Cadete, ... Proteomics 11 (20), 4077-4084, 2011 | 45 | 2011 |
Effect of the Rho kinase inhibitor Y‐27632 on the proteome of hearts with ischemia–reperfusion injury VJJ Cadete, J Sawicka, D Polewicz, A Doroszko, M Wozniak, G Sawicki Proteomics 10 (24), 4377-4385, 2010 | 34 | 2010 |
Effect of the myosin light chain kinase inhibitor ML-7 on the proteome of hearts subjected to ischemia–reperfusion injury H Lin, VJJ Cadete, J Sawicka, M Wozniak, G Sawicki Journal of proteomics 75 (17), 5386-5395, 2012 | 29 | 2012 |
Cardiac hypertrophy in the newborn delays the maturation of fatty acid β-oxidation and compromises postischemic functional recovery T Oka, VH Lam, L Zhang, W Keung, VJJ Cadete, V Samokhvalov, ... American Journal of Physiology-Heart and Circulatory Physiology 302 (9 …, 2012 | 29 | 2012 |
Proteomic analysis of right and left cardiac ventricles under aerobic conditions and after ischemia/reperfusion VJJ Cadete, H Lin, J Sawicka, M Wozniak, G Sawicki Proteomics 12 (14), 2366-2377, 2012 | 28 | 2012 |
Mitochondrial quality control in the cardiac system: an integrative view VJJ Cadete, G Vasam, KJ Menzies, Y Burelle Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (4), 782-796, 2019 | 26 | 2019 |
Inhibition of MMP‐2 expression with siRNA increases baseline cardiomyocyte contractility and protects against simulated ischemic reperfusion injury HB Lin, VJJ Cadete, B Sra, J Sawicka, Z Chen, LK Bekar, F Cayabyab, ... BioMed research international 2014 (1), 810371, 2014 | 24 | 2014 |