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| Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice J Tao, DF Calvisi, S Ranganathan, A Cigliano, L Zhou, S Singh, L Jiang, ... Gastroenterology 147 (3), 690-701, 2014 | 282 | 2014 |
| Impact of water chemistry, pipe material and stagnation on the building plumbing microbiome P Ji, J Parks, MA Edwards, A Pruden PloS one 10 (10), e0141087, 2015 | 164 | 2015 |
| A functional mammalian target of rapamycin complex 1 signaling is indispensable for c‐Myc‐driven hepatocarcinogenesis P Liu, M Ge, J Hu, X Li, L Che, K Sun, L Cheng, Y Huang, MG Pilo, ... Hepatology 66 (1), 167-181, 2017 | 155 | 2017 |
| Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans L Che, W Chi, Y Qiao, J Zhang, X Song, Y Liu, L Li, J Jia, MG Pilo, J Wang, ... Gut 69 (1), 177-186, 2020 | 152 | 2020 |
| A proteomic approach to differentiate histologically classified stable and unstable plaques from human carotid arteries AJ Lepedda, A Cigliano, GM Cherchi, R Spirito, M Maggioni, F Carta, ... Atherosclerosis 203 (1), 112-118, 2009 | 148 | 2009 |
| Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans L Li, GM Pilo, X Li, A Cigliano, G Latte, LI Che, C Joseph, M Mela, C Wang, ... Journal of hepatology 64 (2), 333-341, 2016 | 138 | 2016 |
| Functional crosstalk between AKT/mTOR and Ras/MAPK pathways in hepatocarcinogenesis: implications for the treatment of human liver cancer C Wang, A Cigliano, S Delogu, J Armbruster, F Dombrowski, M Evert, ... Cell cycle 12 (13), 1999-2010, 2013 | 117 | 2013 |
| Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice J Hu, L Che, L Li, MG Pilo, A Cigliano, S Ribback, X Li, G Latte, M Mela, ... Scientific reports 6 (1), 20484, 2016 | 116 | 2016 |
| The mTORC2‐Akt1 cascade is crucial for c‐Myc to promote hepatocarcinogenesis in mice and humans Z Xu, M Xu, P Liu, S Zhang, R Shang, Y Qiao, L Che, S Ribback, ... Hepatology 70 (5), 1600-1613, 2019 | 101 | 2019 |
| Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice S Zhang, X Song, D Cao, Z Xu, B Fan, L Che, J Hu, B Chen, M Dong, ... Journal of hepatology 67 (6), 1194-1203, 2017 | 100 | 2017 |
| TGF-β as multifaceted orchestrator in HCC progression: signaling, EMT, immune microenvironment, and novel therapeutic perspectives F Dituri, S Mancarella, A Cigliano, G Giannelli Seminars in liver disease 39 (01), 053-069, 2019 | 97 | 2019 |
| Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans L Li, L Che, KM Tharp, HM Park, MG Pilo, D Cao, A Cigliano, G Latte, Z Xu, ... Hepatology 63 (6), 1900-1913, 2016 | 92 | 2016 |
| PI3K/AKT/mTOR‐dependent stabilization of oncogenic far‐upstream element binding proteins in hepatocellular carcinoma cells J Samarin, V Laketa, M Malz, S Roessler, I Stein, E Horwitz, S Singer, ... Hepatology 63 (3), 813-826, 2016 | 78 | 2016 |
| 4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N‐Ras proto‐oncogenes in mice C Wang, A Cigliano, L Jiang, X Li, B Fan, MG Pilo, Y Liu, B Gui, M Sini, ... Hepatology 61 (1), 200-213, 2015 | 75 | 2015 |
| Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma R Shang, X Song, P Wang, Y Zhou, X Lu, J Wang, M Xu, X Chen, ... Gut 70 (9), 1746-1757, 2021 | 74 | 2021 |
| Both de novo synthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells D Cao, X Song, L Che, X Li, MG Pilo, G Vidili, A Porcu, A Solinas, ... Liver International 37 (1), 80-89, 2017 | 74 | 2017 |
| Fine structure of glycosaminoglycans from fresh and decellularized porcine cardiac valves and pericardium A Cigliano, A Gandaglia, AJ Lepedda, E Zinellu, F Naso, A Gastaldello, ... Biochemistry research international 2012 (1), 979351, 2012 | 72 | 2012 |
| Combined CDK4/6 and pan-mTOR inhibition is synergistic against intrahepatic cholangiocarcinoma X Song, X Liu, H Wang, J Wang, Y Qiao, A Cigliano, K Utpatel, S Ribback, ... Clinical Cancer Research 25 (1), 403-413, 2019 | 67 | 2019 |
| Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver X Li, J Tao, A Cigliano, M Sini, J Calderaro, D Azoulay, C Wang, Y Liu, ... Oncotarget 6 (12), 10102, 2015 | 65 | 2015 |
