GTP cyclohydrolase 1/tetrahydrobiopterin counteract ferroptosis through lipid remodeling VAN Kraft, CT Bezjian, S Pfeiffer, L Ringelstetter, C Müller, F Zandkarimi, ... ACS central science 6 (1), 41-53, 2019 | 712 | 2019 |
Transferrin receptor is a specific ferroptosis marker H Feng, K Schorpp, J Jin, CE Yozwiak, BG Hoffstrom, AM Decker, ... Cell reports 30 (10), 3411-3423. e7, 2020 | 540 | 2020 |
The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2 A Rybak, H Fuchs, K Hadian, L Smirnova, EA Wulczyn, G Michel, R Nitsch, ... Nature cell biology 11 (12), 1411-1420, 2009 | 292 | 2009 |
Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL D Nagel, S Spranger, M Vincendeau, M Grau, S Raffegerst, B Kloo, ... Cancer cell 22 (6), 825-837, 2012 | 264 | 2012 |
SnapShot: ferroptosis K Hadian, BR Stockwell cell 181 (5), 1188-1188. e1, 2020 | 233 | 2020 |
The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO AK Müller-Rischart, A Pilsl, P Beaudette, M Patra, K Hadian, M Funke, ... Molecular cell 49 (5), 908-921, 2013 | 231 | 2013 |
NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activation K Hadian, RA Griesbach, S Dornauer, TM Wanger, D Nagel, M Metlitzky, ... Journal of Biological Chemistry 286 (29), 26107-26117, 2011 | 128 | 2011 |
Identification of small-molecule frequent hitters from AlphaScreen high-throughput screens K Schorpp, I Rothenaigner, E Salmina, J Reinshagen, T Low, JK Brenke, ... Journal of biomolecular screening 19 (5), 715-726, 2014 | 103 | 2014 |
The therapeutic potential of targeting regulated non-apoptotic cell death K Hadian, BR Stockwell Nature Reviews Drug Discovery 22 (9), 723-742, 2023 | 83 | 2023 |
Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites M Dawidowski, L Emmanouilidis, VC Kalel, K Tripsianes, K Schorpp, ... Science 355 (6332), 1416-1420, 2017 | 80 | 2017 |
Dephosphorylation of Carma1 by PP2A negatively regulates T‐cell activation AC Eitelhuber, S Warth, G Schimmack, M Düwel, K Hadian, K Demski, ... The EMBO journal 30 (3), 594-605, 2011 | 77 | 2011 |
Modulation of human endogenous retrovirus (HERV) transcription during persistent and de novo HIV-1 infection M Vincendeau, I Göttesdorfer, JMH Schreml, AGN Wetie, J Mayer, ... Retrovirology 12, 1-17, 2015 | 73 | 2015 |
Image-based high-content screening in drug discovery S Lin, K Schorpp, I Rothenaigner, K Hadian Drug discovery today 25 (8), 1348-1361, 2020 | 71 | 2020 |
Signals from the nucleus: Activation of NF-κB by cytosolic ATM in the DNA damage response K Hadian, D Krappmann Science signaling 4 (156), pe2-pe2, 2011 | 70 | 2011 |
A 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatment N Anastasov, I Höfig, V Radulović, S Ströbel, M Salomon, J Lichtenberg, ... BMC cancer 15, 1-11, 2015 | 69 | 2015 |
Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity JK Brenke, GM Popowicz, K Schorpp, I Rothenaigner, M Roesner, ... Journal of Biological Chemistry 293 (34), 13191-13203, 2018 | 63 | 2018 |
Post-surgical adhesions are triggered by calcium-dependent membrane bridges between mesothelial surfaces A Fischer, T Koopmans, P Ramesh, S Christ, M Strunz, J Wannemacher, ... Nature communications 11 (1), 3068, 2020 | 60 | 2020 |
Ferroptosis Suppressor Protein 1 (FSP1) and Coenzyme Q10 Cooperatively Suppress Ferroptosis K Hadian Biochemistry 59 (5), 637-638, 2020 | 58 | 2020 |
YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB G Schimmack, K Schorpp, K Kutzner, T Gehring, JK Brenke, K Hadian, ... Elife 6, e22416, 2017 | 58 | 2017 |
Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein K Hadian, M Vincendeau, N Mäusbacher, D Nagel, SM Hauck, M Ueffing, ... Journal of Biological Chemistry 284 (48), 33384-33391, 2009 | 56 | 2009 |