Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling M Hohwieler, A Illing, PC Hermann, T Mayer, M Stockmann, L Perkhofer, ... Gut 66 (3), 473-486, 2017 | 224 | 2017 |
The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation M Kalwa, S Hänzelmann, S Otto, CC Kuo, J Franzen, S Joussen, ... Nucleic acids research 44 (22), 10631-10643, 2016 | 160 | 2016 |
Surface topography guides morphology and spatial patterning of induced pluripotent stem cell colonies G Abagnale, A Sechi, M Steger, Q Zhou, CC Kuo, G Aydin, C Schalla, ... Stem cell reports 9 (2), 654-666, 2017 | 144 | 2017 |
Detection of RNA–DNA binding sites in long noncoding RNAs CC Kuo, S Hänzelmann, N Sentürk Cetin, S Frank, B Zajzon, JP Derks, ... Nucleic acids research 47 (6), e32-e32, 2019 | 143 | 2019 |
Isolation and genome-wide characterization of cellular DNA: RNA triplex structures N Sentürk Cetin, CC Kuo, T Ribarska, R Li, IG Costa, I Grummt Nucleic acids research 47 (5), 2306-2321, 2019 | 90 | 2019 |
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction DJ Trembinski, DI Bink, K Theodorou, J Sommer, A Fischer, A van Bergen, ... Nature communications 11 (1), 2039, 2020 | 75 | 2020 |
New targeted approaches for epigenetic age predictions Y Han, J Franzen, T Stiehl, M Gobs, CC Kuo, M Nikolić, J Hapala, ... BMC biology 18, 1-15, 2020 | 66 | 2020 |
yylncT defines a class of divergently transcribed lncRNAs and safeguards the T-mediated mesodermal commitment of human PSCs S Frank, G Ahuja, D Bartsch, N Russ, W Yao, JCC Kuo, JP Derks, ... Cell stem cell 24 (2), 318-327. e8, 2019 | 55 | 2019 |
DNA methylation changes during long-term in vitro cell culture are caused by epigenetic drift J Franzen, T Georgomanolis, A Selich, CC Kuo, R Stöger, L Brant, ... Communications biology 4 (1), 598, 2021 | 40 | 2021 |
PRDM8 reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation O Cypris, M Eipel, J Franzen, C Rösseler, V Tharmapalan, CC Kuo, ... Clinical epigenetics 12, 1-14, 2020 | 27 | 2020 |
Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l J Lüscher-Firzlaff, N Chatain, CC Kuo, T Braunschweig, A Bochyńska, ... Scientific reports 9 (1), 8262, 2019 | 24 | 2019 |
Variants of DNMT3A cause transcript-specific DNA methylation patterns and affect hematopoiesis T Božić, J Frobel, A Raic, F Ticconi, CC Kuo, S Heilmann-Heimbach, ... Life science alliance 1 (6), 2018 | 22 | 2018 |
HIF1α-AS1 is a DNA: DNA: RNA triplex-forming lncRNA interacting with the HUSH complex MS Leisegang, JK Bains, S Seredinski, JA Oo, NM Krause, CC Kuo, ... Nature communications 13 (1), 6563, 2022 | 21 | 2022 |
Investigation of measurable residual disease in acute myeloid leukemia by DNA methylation patterns T Božić, CC Kuo, J Hapala, J Franzen, M Eipel, U Platzbecker, ... Leukemia 36 (1), 80-89, 2022 | 19 | 2022 |
Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters M Barsoum, AT Stenzel, A Bochyńska, CC Kuo, A Tsompanidis, ... Scientific Reports 12 (1), 21506, 2022 | 7 | 2022 |
A lncrna identifies irf8 enhancer element in negative feedback control of dendritic cell differentiation H Xu, Z Li, CC Kuo, K Götz, T Look, MAS de Toledo, K Seré, IG Costa, ... Elife 12, e83342, 2023 | 6 | 2023 |
Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes A Bochyńska, AT Stenzel, R Sayadi Boroujeni, CC Kuo, M Barsoum, ... Nucleic Acids Research 50 (14), 7889-7905, 2022 | 6 | 2022 |
Triplex domain finder: Detection of triple helix binding domains in long non-coding rnas S Hänzelmann, CC Kuo, M Kalwa, W Wagner, IG Costa bioRxiv, 020297, 2015 | 5 | 2015 |
RGT: a toolbox for the integrative analysis of high throughput regulatory genomics data Z Li, CC Kuo, F Ticconi, M Shaigan, J Gehrmann, EG Gusmao, M Allhoff, ... BMC bioinformatics 24 (1), 79, 2023 | 3 | 2023 |
Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation O Cypris, J Franzen, J Frobel, P Glück, CC Kuo, S Schmitz, S Nüchtern, ... BMC biology 20 (1), 141, 2022 | 3 | 2022 |