CRISPR-Cas9 based engineering of actinomycetal genomes Y Tong, P Charusanti, L Zhang, T Weber, SY Lee ACS synthetic biology 4 (9), 1020-1029, 2015 | 454 | 2015 |
A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules M Liang, Z Li, W Wang, J Liu, L Liu, G Zhu, L Karthik, M Wang, KF Wang, ... Nature communications 10 (1), 3672, 2019 | 348 | 2019 |
Dissemination of antibiotic resistance genes from antibiotic producers to pathogens X Jiang, MMH Ellabaan, P Charusanti, C Munck, K Blin, Y Tong, T Weber, ... Nature communications 8 (1), 15784, 2017 | 324 | 2017 |
Metabolic engineering of antibiotic factories: new tools for antibiotic production in actinomycetes T Weber, P Charusanti, EM Musiol-Kroll, X Jiang, Y Tong, HU Kim, ... Trends in biotechnology 33 (1), 15-26, 2015 | 238 | 2015 |
Synergistic combinations of antifungals and anti-virulence agents to fight against Candida albicans J Cui, B Ren, Y Tong, H Dai, L Zhang Virulence 6 (4), 362-371, 2015 | 182 | 2015 |
Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST Y Tong, CM Whitford, HL Robertsen, K Blin, TS Jørgensen, AK Klitgaard, ... Proceedings of the National Academy of Sciences 116 (41), 20366-20375, 2019 | 161 | 2019 |
White-Opaque Switching in Natural MTLa/α Isolates of Candida albicans: Evolutionary Implications for Roles in Host Adaptation, Pathogenesis, and Sex J Xie, L Tao, CJ Nobile, Y Tong, G Guan, Y Sun, C Cao, AD Hernday, ... PLoS biology 11 (3), e1001525, 2013 | 158 | 2013 |
Synthetic biology and metabolic engineering of actinomycetes for natural product discovery E Palazzotto, Y Tong, SY Lee, T Weber Biotechnology Advances 37 (6), 107366, 2019 | 132 | 2019 |
CRISPR/Cas-based genome engineering in natural product discovery Y Tong, T Weber, SY Lee Natural product reports 36 (9), 1262-1280, 2019 | 107 | 2019 |
Trichodermaketones A−D and 7-O-Methylkoninginin D from the Marine Fungus Trichoderma koningii F Song, H Dai, Y Tong, B Ren, C Chen, N Sun, X Liu, J Bian, M Liu, H Gao, ... Journal of Natural Products 73 (5), 806-810, 2010 | 104 | 2010 |
Roles of Candida albicans Gat2, a GATA-type zinc finger transcription factor, in biofilm formation, filamentous growth and virulence H Du, G Guan, J Xie, Y Sun, Y Tong, L Zhang, G Huang PloS one 7 (1), e29707, 2012 | 87 | 2012 |
N-Acetylglucosamine Induces White-to-Opaque Switching and Mating in Candida tropicalis, Providing New Insights into Adaptation and Fungal Sexual Evolution J Xie, H Du, G Guan, Y Tong, TK Kourkoumpetis, L Zhang, F Bai, G Huang Eukaryotic cell 11 (6), 773-782, 2012 | 74 | 2012 |
CRISPR–Cas9, CRISPRi and CRISPR-BEST-mediated genetic manipulation in streptomycetes Y Tong, CM Whitford, K Blin, TS Jørgensen, T Weber, SY Lee Nature Protocols, 1-33, 2020 | 67 | 2020 |
A versatile genetic engineering toolkit for E. coli based on CRISPR-prime editing Y Tong, TS Jørgensen, CM Whitford, T Weber, SY Lee Nature communications 12 (1), 5206, 2021 | 65 | 2021 |
A versatile biosensing platform coupling CRISPR–Cas12a and aptamers for detection of diverse analytes X Zhao, S Li, G Liu, Z Wang, Z Yang, Q Zhang, M Liang, J Liu, Z Li, Y Tong, ... Science Bulletin 66 (1), 69-77, 2021 | 54 | 2021 |
Quinazolin-4-one Coupled with Pyrrolidin-2-iminium Alkaloids from Marine-Derived Fungus Penicillium aurantiogriseum F Song, B Ren, K Yu, C Chen, H Guo, N Yang, H Gao, X Liu, M Liu, ... Marine drugs 10 (6), 1297-1306, 2012 | 53 | 2012 |
Bcr1 plays a central role in the regulation of opaque cell filamentation in Candida albicans G Guan, J Xie, L Tao, CJ Nobile, Y Sun, C Cao, Y Tong, G Huang Molecular microbiology 89 (4), 732-750, 2013 | 50 | 2013 |
Beauvericin counteracted multi-drug resistant Candida albicans by blocking ABC transporters Y Tong, M Liu, Y Zhang, X Liu, R Huang, F Song, H Dai, B Ren, N Sun, ... Synthetic and systems biotechnology 1 (3), 158-168, 2016 | 40 | 2016 |
Antiviral activity of an isatin derivative via induction of PERK-Nrf2-mediated suppression of cap-independent translation HM Zhang, H Dai, PJ Hanson, H Li, H Guo, X Ye, MG Hemida, L Wang, ... ACS chemical biology 9 (4), 1015-1024, 2014 | 39 | 2014 |
Activating cryptic biosynthetic gene cluster through a CRISPR–Cas12a-mediated direct cloning approach M Liang, L Liu, F Xu, X Zeng, R Wang, J Yang, W Wang, L Karthik, J Liu, ... Nucleic Acids Research 50 (6), 3581-3592, 2022 | 36 | 2022 |