Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer M Soda, YL Choi, M Enomoto, S Takada, Y Yamashita, S Ishikawa, ... Nature 448 (7153), 561-566, 2007 | 6420 | 2007 |
Global variation in copy number in the human genome R Redon, S Ishikawa, KR Fitch, L Feuk, GH Perry, TD Andrews, H Fiegler, ... nature 444 (7118), 444-454, 2006 | 5428 | 2006 |
Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member JD Brook, ME McCurrach, HG Harley, AJ Buckler, D Church, H Aburatani, ... Cell 68 (4), 799-808, 1992 | 3325 | 1992 |
Comprehensive and integrative genomic characterization of hepatocellular carcinoma A Ally, M Balasundaram, R Carlsen, E Chuah, A Clarke, N Dhalla, RA Holt, ... Cell 169 (7), 1327-1341. e23, 2017 | 1930 | 2017 |
Landscape of genetic lesions in 944 patients with myelodysplastic syndromes T Haferlach, Y Nagata, V Grossmann, Y Okuno, U Bacher, G Nagae, ... Leukemia 28 (2), 241-247, 2014 | 1682 | 2014 |
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1561 | 2020 |
A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection H Suzuki, Y Kurihara, M Takeya, N Kamada, M Kataoka, K Jishage, ... Nature 386 (6622), 292-296, 1997 | 1520 | 1997 |
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma BE Johnson, T Mazor, C Hong, M Barnes, K Aihara, CY McLean, ... Science 343 (6167), 189-193, 2014 | 1436 | 2014 |
Cohesin mediates transcriptional insulation by CCCTC-binding factor KS Wendt, K Yoshida, T Itoh, M Bando, B Koch, E Schirghuber, ... Nature 451 (7180), 796-801, 2008 | 1375 | 2008 |
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming Y Mitsuishi, K Taguchi, Y Kawatani, T Shibata, T Nukiwa, H Aburatani, ... Cancer cell 22 (1), 66-79, 2012 | 1367 | 2012 |
Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis S Hiratsuka, A Watanabe, H Aburatani, Y Maru Nature cell biology 8 (12), 1369-1375, 2006 | 1233 | 2006 |
Integrated molecular analysis of clear-cell renal cell carcinoma Y Sato, T Yoshizato, Y Shiraishi, S Maekawa, Y Okuno, T Kamura, ... Nature genetics 45 (8), 860-867, 2013 | 1178 | 2013 |
Copy number variation: new insights in genome diversity JL Freeman, GH Perry, L Feuk, R Redon, SA McCarroll, DM Altshuler, ... Genome research 16 (8), 949-961, 2006 | 1167 | 2006 |
Engineered CRISPR-Cas9 nuclease with expanded targeting space H Nishimasu, X Shi, S Ishiguro, L Gao, S Hirano, S Okazaki, T Noda, ... Science 361 (6408), 1259-1262, 2018 | 1034 | 2018 |
Integrated molecular analysis of adult T cell leukemia/lymphoma K Kataoka, Y Nagata, A Kitanaka, Y Shiraishi, T Shimamura, J Yasunaga, ... Nature genetics 47 (11), 1304-1315, 2015 | 814 | 2015 |
Trans-ancestry mutational landscape of hepatocellular carcinoma genomes Y Totoki, K Tatsuno, KR Covington, H Ueda, CJ Creighton, M Kato, S Tsuji, ... Nature genetics 46 (12), 1267-1273, 2014 | 785 | 2014 |
The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase S Hiratsuka, A Watanabe, Y Sakurai, S Akashi-Takamura, S Ishibashi, ... Nature cell biology 10 (11), 1349-1355, 2008 | 742 | 2008 |
Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer A Fujimoto, M Furuta, Y Totoki, T Tsunoda, M Kato, Y Shiraishi, H Tanaka, ... Nature genetics 48 (5), 500-509, 2016 | 695 | 2016 |
Skeletal muscle Foxo1 (Fkhr) transgenic mice have less skeletal muscle mass, down-regulated type I (Slow twitch/red muscle) fiber genes, and impaired glycemic control*[Boxs] Y Kamei, S Miura, M Suzuki, Y Kai, J Mizukami, T Taniguchi, K Mochida, ... Journal of Biological Chemistry 279 (39), 41114-41123, 2004 | 691 | 2004 |
Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos K Matsuo, DL Galson, C Zhao, L Peng, C Laplace, KZQ Wang, ... Journal of Biological Chemistry 279 (25), 26475-26480, 2004 | 628 | 2004 |