Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 5569 | 2018 |
Bax, Bak and beyond—mitochondrial performance in apoptosis A Peña‐Blanco, AJ García‐Sáez The FEBS journal 285 (3), 416-431, 2018 | 740 | 2018 |
Effect of line tension on the lateral organization of lipid membranes AJ García-Sáez, S Chiantia, P Schwille Journal of Biological Chemistry 282 (46), 33537-33544, 2007 | 484 | 2007 |
The secrets of the Bcl-2 family AJ García-Sáez Cell Death & Differentiation 19 (11), 1733-1740, 2012 | 315 | 2012 |
Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores R Salvador‐Gallego, M Mund, K Cosentino, J Schneider, J Unsay, ... The EMBO journal 35 (4), 389-401, 2016 | 288 | 2016 |
Structural model of active Bax at the membrane S Bleicken, G Jeschke, C Stegmueller, R Salvador-Gallego, ... Molecular cell 56 (4), 496-505, 2014 | 229 | 2014 |
Bax and Bak pores: are we closing the circle? K Cosentino, AJ García-Sáez Trends in cell biology 27 (4), 266-275, 2017 | 201 | 2017 |
Ferroptotic pores induce Ca2+ fluxes and ESCRT-III activation to modulate cell death kinetics L Pedrera, RA Espiritu, U Ros, J Weber, A Schmitt, J Stroh, S Hailfinger, ... Cell Death & Differentiation 28 (5), 1644-1657, 2021 | 194 | 2021 |
Mitochondrial alterations in apoptosis K Cosentino, AJ García-Sáez Chemistry and physics of lipids 181, 62-75, 2014 | 192 | 2014 |
Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species Y Subburaj, K Cosentino, M Axmann, E Pedrueza-Villalmanzo, ... Nature communications 6 (1), 8042, 2015 | 175 | 2015 |
Membrane-insertion fragments of Bcl-xL, Bax, and Bid AJ García-Sáez, I Mingarro, E Pérez-Payá, J Salgado Biochemistry 43 (34), 10930-10943, 2004 | 175 | 2004 |
Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM AJ García-Sáez, S Chiantia, J Salgado, P Schwille Biophysical journal 93 (1), 103-112, 2007 | 167 | 2007 |
Proapoptotic Bax and Bak proteins form stable protein-permeable pores of tunable size S Bleicken, O Landeta, A Landajuela, G Basañez, AJ García-Sáez Journal of Biological Chemistry 288 (46), 33241-33252, 2013 | 161 | 2013 |
Cardiolipin effects on membrane structure and dynamics JD Unsay, K Cosentino, Y Subburaj, AJ García-Sáez Langmuir 29 (51), 15878-15887, 2013 | 158 | 2013 |
Membrane promotes tBID interaction with BCLXL AJ García-Sáez, J Ries, M Orzáez, E Pérez-Payà, P Schwille Nature structural & molecular biology 16 (11), 1178-1185, 2009 | 158 | 2009 |
Equinatoxin II permeabilizing activity depends on the presence of sphingomyelin and lipid phase coexistence P Schön, AJ García-Sáez, P Malovrh, K Bacia, G Anderluh, P Schwille Biophysical Journal 95 (2), 691-698, 2008 | 142 | 2008 |
Pore formation in regulated cell death H Flores‐Romero, U Ros, AJ Garcia‐Saez The EMBO journal 39 (23), e105753, 2020 | 140 | 2020 |
Yeast lipids can phase-separate into micrometer-scale membrane domains C Klose, CS Ejsing, AJ García-Sáez, HJ Kaiser, JL Sampaio, MA Surma, ... Journal of Biological Chemistry 285 (39), 30224-30232, 2010 | 133 | 2010 |
Fluorescence correlation spectroscopy for the study of membrane dynamics and protein/lipid interactions AJ García-Sáez, P Schwille Methods 46 (2), 116-122, 2008 | 130 | 2008 |
Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores AJ García‐Sáez, M Coraiola, MD Serra, I Mingarro, P Müller, J Salgado The FEBS journal 273 (5), 971-981, 2006 | 130 | 2006 |