W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity JD Hulzinga, L Thuneberg, M Klüppel, J Malysz, HB Mikkelsen, ... Nature 373 (6512), 347-349, 1995 | 1678 | 1995 |
Distinct profiles of α7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes JH Grønlien, M Håkerud, H Ween, K Thorin-Hagene, CA Briggs, ... Molecular pharmacology 72 (3), 715-724, 2007 | 320 | 2007 |
An allosteric modulator of the α7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo DB Timmermann, JH Grønlien, KL Kohlhaas, EØ Nielsen, E Dam, ... Journal of Pharmacology and Experimental Therapeutics 323 (1), 294-307, 2007 | 306 | 2007 |
Interstitial cells of Cajal direct normal propulsive contractile activity in the mouse small intestine T Der–Silaphet, J Malysz, S Hagel, AL Arsenault, JD Huizinga Gastroenterology 114 (4), 724-736, 1998 | 290 | 1998 |
Developmental origin and Kit-dependent development of the interstitial cells of Cajal in the mammalian small intestine M Kluppel, JD Huizinga, J Malysz, A Bernstein Developmental dynamics 211, 60-71, 1998 | 289 | 1998 |
Broad-spectrum efficacy across cognitive domains by α7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways RS Bitner, WH Bunnelle, DJ Anderson, CA Briggs, J Buccafusco, ... Journal of Neuroscience 27 (39), 10578-10587, 2007 | 271 | 2007 |
In vitro pharmacological characterization of a novel selective α7 neuronal nicotinic acetylcholine receptor agonist ABT-107 J. Pharmacol. Exp. Ther. 334 (3), 863, 2010 | 163* | 2010 |
Regulation of slow wave frequency by IP3-sensitive calcium release in the murine small intestine J Malysz, G Donnelly, JD Huizinga American Journal of Physiology-Gastrointestinal and Liver Physiology 280 (3 …, 2001 | 130 | 2001 |
Action potential generation in the small intestine of W mutant mice that lack interstitial cells of Cajal J Malysz, L Thuneberg, HB Mikkelsen, JD Huizinga American Journal of Physiology-Gastrointestinal and Liver Physiology 271 (3 …, 1996 | 121 | 1996 |
Local presentation of Steel factor increases expression of c-kit immunoreactive interstitial cells of Cajal in culture A Rich, SM Miller, SJ Gibbons, J Malysz, JH Szurszewski, G Farrugia American Journal of Physiology-Gastrointestinal and Liver Physiology 284 (2 …, 2003 | 112 | 2003 |
Preclinical characterization of A‐582941: A novel α7 neuronal nicotinic receptor agonist with broad spectrum cognition‐enhancing properties KR Tietje, DJ Anderson, RS Bitner, EA Blomme, PJ Brackemeyer, ... CNS neuroscience & therapeutics 14 (1), 65-82, 2008 | 102 | 2008 |
Conditional genetic deletion of Ano1 in interstitial cells of Cajal impairs Ca2+ transients and slow waves in adult mouse small intestine J Malysz, SJ Gibbons, SA Saravanaperumal, P Du, ST Eisenman, C Cao, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 312 (3 …, 2017 | 91 | 2017 |
Role of channel activation in cognitive enhancement mediated by α7 nicotinic acetylcholine receptors CA Briggs, JH Grønlien, P Curzon, DB Timmermann, H Ween, ... British journal of pharmacology 158 (6), 1486-1494, 2009 | 79 | 2009 |
Corporeal structural and vascular micro architecture with X-ray micro computerized tomography in normal and diabetic rabbits: histopathological correlation DN Simopoulos, SJ Gibbons, J Malysz, JH Szurszewski, G Farrugia, ... The Journal of urology 165 (5), 1776-1782, 2001 | 79 | 2001 |
Action potential generation, Kit receptor immunohistochemistry and morphology of steel‐Dickie (Sl/Sld) mutant mouse small intestine MIKKELSEN, MALYSZ, HUIZINGA, THUNEBERG Neurogastroenterology & Motility 10 (1), 11-26, 1998 | 77 | 1998 |
In vitro pharmacological characterization of a novel allosteric modulator of α7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl … J Malysz, JH Grønlien, DJ Anderson, M Håkerud, K Thorin-Hagene, ... Journal of Pharmacology and Experimental Therapeutics 330 (1), 257-267, 2009 | 76 | 2009 |
α4β2 neuronal nicotinic receptor positive allosteric modulation: an approach for improving the therapeutic index of α4β2 nAChR agonists in pain CH Lee, C Zhu, J Malysz, T Campbell, T Shaughnessy, P Honore, ... Biochemical pharmacology 82 (8), 959-966, 2011 | 75 | 2011 |
Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the α7 … R Faghih, SM Gopalakrishnan, JH Gronlien, J Malysz, CA Briggs, ... Journal of medicinal chemistry 52 (10), 3377-3384, 2009 | 73 | 2009 |
Functional characterization of large conductance calcium-activated K+ channel openers in bladder and vascular smooth muscle J Malysz, SA Buckner, AV Daza, I Milicic, A Perez-Medrano, ... Naunyn-Schmiedeberg's archives of pharmacology 369, 481-489, 2004 | 61 | 2004 |
α7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues CA Briggs, MR Schrimpf, DJ Anderson, EJ Gubbins, JH Grønlien, ... British journal of pharmacology 153 (5), 1054-1061, 2008 | 56 | 2008 |