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John Malysz
John Malysz
McMaster Univ., Mayo Clinic, Abbott, Univ. South Carolina
在 mayo.edu 的电子邮件经过验证
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引用次数
引用次数
年份
W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity
JD Hulzinga, L Thuneberg, M Klüppel, J Malysz, HB Mikkelsen, ...
Nature 373 (6512), 347-349, 1995
16781995
Distinct profiles of α7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes
JH Grønlien, M Håkerud, H Ween, K Thorin-Hagene, CA Briggs, ...
Molecular pharmacology 72 (3), 715-724, 2007
3202007
An allosteric modulator of the α7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo
DB Timmermann, JH Grønlien, KL Kohlhaas, EØ Nielsen, E Dam, ...
Journal of Pharmacology and Experimental Therapeutics 323 (1), 294-307, 2007
3062007
Interstitial cells of Cajal direct normal propulsive contractile activity in the mouse small intestine
T Der–Silaphet, J Malysz, S Hagel, AL Arsenault, JD Huizinga
Gastroenterology 114 (4), 724-736, 1998
2901998
Developmental origin and Kit-dependent development of the interstitial cells of Cajal in the mammalian small intestine
M Kluppel, JD Huizinga, J Malysz, A Bernstein
Developmental dynamics 211, 60-71, 1998
2891998
Broad-spectrum efficacy across cognitive domains by α7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways
RS Bitner, WH Bunnelle, DJ Anderson, CA Briggs, J Buccafusco, ...
Journal of Neuroscience 27 (39), 10578-10587, 2007
2712007
In vitro pharmacological characterization of a novel selective α7 neuronal nicotinic acetylcholine receptor agonist ABT-107
J. Pharmacol. Exp. Ther. 334 (3), 863, 2010
163*2010
Regulation of slow wave frequency by IP3-sensitive calcium release in the murine small intestine
J Malysz, G Donnelly, JD Huizinga
American Journal of Physiology-Gastrointestinal and Liver Physiology 280 (3 …, 2001
1302001
Action potential generation in the small intestine of W mutant mice that lack interstitial cells of Cajal
J Malysz, L Thuneberg, HB Mikkelsen, JD Huizinga
American Journal of Physiology-Gastrointestinal and Liver Physiology 271 (3 …, 1996
1211996
Local presentation of Steel factor increases expression of c-kit immunoreactive interstitial cells of Cajal in culture
A Rich, SM Miller, SJ Gibbons, J Malysz, JH Szurszewski, G Farrugia
American Journal of Physiology-Gastrointestinal and Liver Physiology 284 (2 …, 2003
1122003
Preclinical characterization of A‐582941: A novel α7 neuronal nicotinic receptor agonist with broad spectrum cognition‐enhancing properties
KR Tietje, DJ Anderson, RS Bitner, EA Blomme, PJ Brackemeyer, ...
CNS neuroscience & therapeutics 14 (1), 65-82, 2008
1022008
Conditional genetic deletion of Ano1 in interstitial cells of Cajal impairs Ca2+ transients and slow waves in adult mouse small intestine
J Malysz, SJ Gibbons, SA Saravanaperumal, P Du, ST Eisenman, C Cao, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 312 (3 …, 2017
912017
Role of channel activation in cognitive enhancement mediated by α7 nicotinic acetylcholine receptors
CA Briggs, JH Grønlien, P Curzon, DB Timmermann, H Ween, ...
British journal of pharmacology 158 (6), 1486-1494, 2009
792009
Corporeal structural and vascular micro architecture with X-ray micro computerized tomography in normal and diabetic rabbits: histopathological correlation
DN Simopoulos, SJ Gibbons, J Malysz, JH Szurszewski, G Farrugia, ...
The Journal of urology 165 (5), 1776-1782, 2001
792001
Action potential generation, Kit receptor immunohistochemistry and morphology of steel‐Dickie (Sl/Sld) mutant mouse small intestine
MIKKELSEN, MALYSZ, HUIZINGA, THUNEBERG
Neurogastroenterology & Motility 10 (1), 11-26, 1998
771998
In vitro pharmacological characterization of a novel allosteric modulator of α7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl …
J Malysz, JH Grønlien, DJ Anderson, M Håkerud, K Thorin-Hagene, ...
Journal of Pharmacology and Experimental Therapeutics 330 (1), 257-267, 2009
762009
α4β2 neuronal nicotinic receptor positive allosteric modulation: an approach for improving the therapeutic index of α4β2 nAChR agonists in pain
CH Lee, C Zhu, J Malysz, T Campbell, T Shaughnessy, P Honore, ...
Biochemical pharmacology 82 (8), 959-966, 2011
752011
Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the α7 …
R Faghih, SM Gopalakrishnan, JH Gronlien, J Malysz, CA Briggs, ...
Journal of medicinal chemistry 52 (10), 3377-3384, 2009
732009
Functional characterization of large conductance calcium-activated K+ channel openers in bladder and vascular smooth muscle
J Malysz, SA Buckner, AV Daza, I Milicic, A Perez-Medrano, ...
Naunyn-Schmiedeberg's archives of pharmacology 369, 481-489, 2004
612004
α7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues
CA Briggs, MR Schrimpf, DJ Anderson, EJ Gubbins, JH Grønlien, ...
British journal of pharmacology 153 (5), 1054-1061, 2008
562008
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