Systems biology analysis reveals eight SLC22 transporter subgroups, including OATs, OCTs, and OCTNs DC Engelhart, JC Granados, D Shi, MH Saier Jr, ME Baker, R Abagyan, ... International journal of molecular sciences 21 (5), 1791, 2020 | 52 | 2020 |
Multislice CEST MRI improves the spatial assessment of tumor pH EA Randtke, JC Granados, CM Howison, MD Pagel, ... Magnetic resonance in medicine 78 (1), 97-106, 2017 | 35 | 2017 |
Blockade of organic anion transport in humans after treatment with the drug probenecid leads to major metabolic alterations in plasma and urine JC Granados, V Bhatnagar, SK Nigam Clinical Pharmacology & Therapeutics 112 (3), 653-664, 2022 | 33 | 2022 |
Drosophila SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress DC Engelhart, P Azad, S Ali, JC Granados, GG Haddad, SK Nigam International Journal of Molecular Sciences 21 (6), 2002, 2020 | 32 | 2020 |
AHR is a master regulator of diverse pathways in endogenous metabolism JC Granados, K Falah, I Koo, EW Morgan, GH Perdew, AD Patterson, ... Scientific reports 12 (1), 16625, 2022 | 31 | 2022 |
Coordinate regulation of systemic and kidney tryptophan metabolism by the drug transporters OAT1 and OAT3 JC Granados, A Richelle, JM Gutierrez, P Zhang, X Zhang, V Bhatnagar, ... Journal of Biological Chemistry 296, 2021 | 28 | 2021 |
A key role for the transporter OAT1 in systemic lipid metabolism JC Granados, AK Nigam, KT Bush, N Jamshidi, SK Nigam Journal of Biological Chemistry 296, 2021 | 26 | 2021 |
OAT, OATP, and MRP drug transporters and the remote sensing and signaling theory SK Nigam, JC Granados Annual review of pharmacology and toxicology 63 (1), 637-660, 2023 | 25 | 2023 |
Renal and non-renal response of ABC and SLC transporters in chronic kidney disease AM Torres, AV Dnyanmote, JC Granados, SK Nigam Expert Opinion on Drug Metabolism & Toxicology 17 (5), 515-542, 2021 | 24 | 2021 |
A biological basis for pharmacokinetics: the remote sensing and signaling theory SK Nigam, JC Granados Clinical pharmacology and therapeutics 112 (3), 456, 2022 | 11 | 2022 |
The kidney drug transporter OAT1 regulates gut microbiome–dependent host metabolism JC Granados, V Ermakov, K Maity, DR Vera, G Chang, SK Nigam JCI insight 8 (2), 2023 | 8 | 2023 |
Regulation of human endogenous metabolites by drug transporters and drug metabolizing enzymes: an analysis of targeted SNP-metabolite associations JC Granados, JD Watrous, T Long, SB Rosenthal, S Cheng, M Jain, ... Metabolites 13 (2), 171, 2023 | 5 | 2023 |
Remote effects of kidney drug transporter OAT1 on gut microbiome composition and urate homeostasis VS Ermakov, JC Granados, SK Nigam JCI insight 8 (21), 2023 | 4 | 2023 |
In Vivo Regulation of Small Molecule Natural Products, Antioxidants, and Nutrients by OAT1 and OAT3 K Falah, P Zhang, AK Nigam, K Maity, G Chang, JC Granados, ... Nutrients 16 (14), 2242, 2024 | 1 | 2024 |
Organic anion transporters in remote sensing and organ crosstalk JC Granados, SK Nigam Pharmacology & Therapeutics, 108723, 2024 | | 2024 |
Uncovering the physiological function of drug transporters JC Granados University of California, San Diego, 2023 | | 2023 |
ORGANIC ANION TRANSPORTERS (OATs) JC Granados, J Zhang, G You, SK Nigam Drug Transporters: Molecular Characterization and Role in Drug Disposition …, 2022 | | 2022 |
Coordinate regulation of systemic and kidney tryptophan metabolism by the drug JC Granados, A Richelle, JM Gutierrez | | 2021 |