Primary cilia are not calcium-responsive mechanosensors M Delling, AA Indzhykulian, X Liu, Y Li, T Xie, DP Corey, DE Clapham Nature 531 (7596), 656-660, 2016 | 390 | 2016 |
Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c B Pan, C Askew, A Galvin, S Heman-Ackah, Y Asai, AA Indzhykulian, ... Nature biotechnology 35 (3), 264-272, 2017 | 278 | 2017 |
Alterations of the CIB2 calcium-and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48 S Riazuddin, IA Belyantseva, APJ Giese, K Lee, AA Indzhykulian, ... Nature genetics 44 (11), 1265-1271, 2012 | 258 | 2012 |
Rescue of hearing by gene delivery to inner-ear hair cells using exosome-associated AAV B György, C Sage, AA Indzhykulian, DI Scheffer, AR Brisson, S Tan, X Wu, ... Molecular Therapy 25 (2), 379-391, 2017 | 201 | 2017 |
Gene transfer with AAV9-PHP. B rescues hearing in a mouse model of usher syndrome 3A and transduces hair cells in a non-human primate B György, EJ Meijer, MV Ivanchenko, K Tenneson, F Emond, KS Hanlon, ... Molecular Therapy-Methods & Clinical Development 13, 1-13, 2019 | 137 | 2019 |
Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells AA Indzhykulian, R Stepanyan, A Nelina, KJ Spinelli, ZM Ahmed, ... PLoS biology 11 (6), e1001583, 2013 | 128 | 2013 |
Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells AC Velez-Ortega, MJ Freeman, AA Indzhykulian, JM Grossheim, ... Elife 6, e24661, 2017 | 88 | 2017 |
Renewed proliferation in adult mouse cochlea and regeneration of hair cells Y Shu, W Li, M Huang, YZ Quan, D Scheffer, C Tian, Y Tao, X Liu, ... Nature communications 10 (1), 5530, 2019 | 86 | 2019 |
TRPA1-mediated accumulation of aminoglycosides in mouse cochlear outer hair cells RS Stepanyan, AA Indzhykulian, AC Vélez-Ortega, ET Boger, PS Steyger, ... Journal of the Association for Research in Otolaryngology 12, 729-740, 2011 | 81 | 2011 |
The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing Q Fang, AA Indzhykulian, M Mustapha, GP Riordan, DF Dolan, ... Elife 4, e08627, 2015 | 74 | 2015 |
Tryptophan‐rich basic protein (WRB) mediates insertion of the tail‐anchored protein otoferlin and is required for hair cell exocytosis and hearing C Vogl, I Panou, G Yamanbaeva, C Wichmann, SJ Mangosing, F Vilardi, ... The EMBO Journal 35 (23), 2536-2552, 2016 | 66 | 2016 |
XIRP2, an actin-binding protein essential for inner ear hair-cell stereocilia DI Scheffer, DS Zhang, J Shen, A Indzhykulian, KD Karavitaki, YJ Xu, ... Cell reports 10 (11), 1811-1818, 2015 | 41 | 2015 |
Hair-cell mechanotransduction persists in TRP channel knockout mice X Wu, AA Indzhykulian, PD Niksch, RM Webber, M Garcia-Gonzalez, ... PloS one 11 (5), e0155577, 2016 | 31 | 2016 |
PKHD1L1 is a coat protein of hair-cell stereocilia and is required for normal hearing X Wu, MV Ivanchenko, H Al Jandal, M Cicconet, AA Indzhykulian, ... Nature Communications 10 (1), 3801, 2019 | 29 | 2019 |
Electron microscopy techniques for investigating structure and composition of hair-cell stereociliary bundles MV Ivanchenko, AA Indzhykulian, DP Corey Frontiers in Cell and Developmental Biology 9, 744248, 2021 | 17 | 2021 |
Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F MV Ivanchenko, DM Hathaway, AJ Klein, B Pan, O Strelkova, ... Nature Communications 14 (1), 2400, 2023 | 16 | 2023 |
Norrie disease protein is essential for cochlear hair cell maturation Y Hayashi, H Chiang, CJ Tian, AA Indzhykulian, ASB Edge Proceedings of the National Academy of Sciences 118 (39), e2106369118, 2021 | 13 | 2021 |
Mechanical overstimulation causes acute injury and synapse loss followed by fast recovery in lateral-line neuromasts of larval zebrafish M Holmgren, ME Ravicz, KE Hancock, O Strelkova, D Kallogjeri, ... elife 10, e69264, 2021 | 12 | 2021 |
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice YZ Quan, W Wei, V Ergin, AP Rameshbabu, M Huang, C Tian, SV Saladi, ... Proceedings of the National Academy of Sciences 120 (17), e2215253120, 2023 | 11 | 2023 |
Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F CW Peters, KS Hanlon, MV Ivanchenko, E Zinn, EF Linarte, Y Li, JM Levy, ... Molecular Therapy 31 (8), 2439-2453, 2023 | 9 | 2023 |