| A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity JB Bramsen, MB Laursen, AF Nielsen, TB Hansen, C Bus, N Langkjær, ... Nucleic acids research 37 (9), 2867-2881, 2009 | 445 | 2009 |
| How do the gauche and anomeric effects drive the pseudorotational equilibrium of the pentofuranose moiety of nucleosides? J Plavec, W Tong, J Chattopadhyaya Journal of the American Chemical Society 115 (21), 9734-9746, 1993 | 246 | 1993 |
| Structure and toxicity of a peptide hepatotoxin from the cyanobacterium Oscillatoria agardhii JAO Meriluoto, A Sandström, JE Eriksson, G Remaud, AG Graig, ... Toxicon 27 (9), 1021-1034, 1989 | 207 | 1989 |
| A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects JB Bramsen, MM Pakula, TB Hansen, C Bus, N Langkjær, D Odadzic, ... Nucleic acids research 38 (17), 5761-5773, 2010 | 203 | 2010 |
| A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H E Zamaratski, PI Pradeepkumar, J Chattopadhyaya Journal of biochemical and biophysical methods 48 (3), 189-208, 2001 | 184 | 2001 |
| A new generalized Karplus-type equation relating vicinal proton-fluorine coupling constants to H− C− C− F torsion angles C Thibaudeau, J Plavec, J Chattopadhyaya The Journal of Organic Chemistry 63 (15), 4967-4984, 1998 | 184 | 1998 |
| Design, synthesis, biological evaluation and molecular modelling studies of novel quinoline derivatives against Mycobacterium tuberculosis RS Upadhayaya, JK Vandavasi, NR Vasireddy, V Sharma, SS Dixit, ... Bioorganic & medicinal chemistry 17 (7), 2830-2841, 2009 | 177 | 2009 |
| Design, synthesis and biological evaluation of novel triazole, urea and thiourea derivatives of quinoline against Mycobacterium tuberculosis RS Upadhayaya, GM Kulkarni, NR Vasireddy, JK Vandavasi, SS Dixit, ... Bioorganic & medicinal chemistry 17 (13), 4681-4692, 2009 | 174 | 2009 |
| Allele-Selective Inhibition of Mutant Huntingtin Expression with Antisense Oligonucleotides Targeting the Expanded CAG Repeat KT Gagnon, HM Pendergraff, GF Deleavey, EE Swayze, P Potier, ... Biochemistry 49 (47), 10166-10178, 2010 | 167 | 2010 |
| Novel quinoline and naphthalene derivatives as potent antimycobacterial agents RS Upadhayaya, JK Vandavasi, RA Kardile, SV Lahore, SS Dixit, ... European journal of medicinal chemistry 45 (5), 1854-1867, 2010 | 144 | 2010 |
| Stereoelectronic effects in nucleosides and nucleotides and their structural implications C Thibaudeau, J Chattopadhyaya Uppsala University Press, 1999 | 123 | 1999 |
| How does the electronegativity of the substituent dictate the strength of the gauche effect? C Thibaudeau, J Plavec, N Garg, A Papchikhin, J Chattopadhyaya Journal of the American Chemical Society 116 (9), 4038-4043, 1994 | 120 | 1994 |
| Single-stranded adenine-rich DNA and RNA retain structural characteristics of their respective double-stranded conformations and show directional differences in stacking pattern J Isaksson, S Acharya, J Barman, P Cheruku, J Chattopadhyaya Biochemistry 43 (51), 15996-16010, 2004 | 116 | 2004 |
| The pKa's of 2‘-Hydroxyl Group in Nucleosides and Nucleotides I Velikyan, S Acharya, A Trifonova, A Földesi, J Chattopadhyaya Journal of the American Chemical Society 123 (12), 2893-2894, 2001 | 114 | 2001 |
| How Does the 2'-Hydroxy Group Drive the Pseudorotational Equilibrium in Nucleoside and Nucleotide by the Tuning of the 3'-Gauche Effect? J Plavec, C Thibaudeau, J Chattopadhyaya Journal of the American Chemical Society 116 (15), 6558-6560, 1994 | 114 | 1994 |
| Rapid and quantitative recovery of DNA fragments from gels by displacement electrophoresis (isotachophoresis) LG Öfverstedt, K Hammarström, N Balgobin, S Hjertén, U Pettersson, ... Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 782 (2 …, 1984 | 107 | 1984 |
| Inhibition of the reverse transcriptase from HIV by 3′-azido-3′-deoxythymidine triphosphate and its threo analogue L Vrang, H Bazin, G Remaud, J Chattopadhyaya, B Öberg Antiviral research 7 (3), 139-149, 1987 | 106 | 1987 |
| Five- and Six-Membered Conformationally Locked 2‘,4‘-Carbocyclic ribo-Thymidines: Synthesis, Structure, and Biochemical Studies P Srivastava, J Barman, W Pathmasiri, O Plashkevych, M Wenska, ... Journal of the American Chemical Society 129 (26), 8362-8379, 2007 | 103 | 2007 |
| Chemical synthesis of a tridecanucleoside dodecaphosphate sequence of SV40 DNA JB Chattopadhyaya, CB Reese Nucleic Acids Research 8 (9), 2039-2053, 1980 | 101 | 1980 |
| Measurement of Nucleobase pKa Values in Model Mononucleotides Shows RNA−RNA Duplexes To Be More Stable than DNA−DNA Duplexes P Acharya, P Cheruku, S Chatterjee, S Acharya, J Chattopadhyaya Journal of the American Chemical Society 126 (9), 2862-2869, 2004 | 99 | 2004 |
