Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes S Poepsel, V Kasinath, E Nogales Nature structural & molecular biology 25 (2), 154-162, 2018 | 212 | 2018 |
Structures of human PRC2 with its cofactors AEBP2 and JARID2 V Kasinath, M Faini, S Poepsel, D Reif, A Feng, G Stjepanovic, ... Science, 2018 | 203 | 2018 |
Entropy in molecular recognition by proteins JA Caro, KW Harpole, V Kasinath, J Lim, J Granja, KG Valentine, ... Proceedings of the National Academy of Sciences 114 (25), 6563-6568, 2017 | 168 | 2017 |
JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications V Kasinath, C Beck, P Sauer, S Poepsel, J Kosmatka, M Faini, D Toso, ... Science 371 (6527), eabc3393, 2021 | 165 | 2021 |
Microscopic insights into the NMR relaxation-based protein conformational entropy meter V Kasinath, KA Sharp, AJ Wand Journal of the American Chemical Society 135 (40), 15092-15100, 2013 | 132 | 2013 |
Coupled motion in proteins revealed by pressure perturbation Y Fu, V Kasinath, VR Moorman, NV Nucci, VJ Hilser, AJ Wand Journal of the American Chemical Society 134 (20), 8543-8550, 2012 | 104 | 2012 |
The I‐tetraplex building block: rational design and controlled fabrication of robust 1D DNA scaffolds through non‐Watson–Crick interactions HB Ghodke, R Krishnan, K Vignesh, GVP Kumar, C Narayana, Y Krishnan Angewandte Chemie International Edition 46 (15), 2646-2649, 2007 | 80 | 2007 |
On the relationship between NMR‐derived amide order parameters and protein backbone entropy changes KA Sharp, E O'Brien, V Kasinath, AJ Wand Proteins: Structure, Function, and Bioinformatics 83 (5), 922-930, 2015 | 69 | 2015 |
A 13C Labeling Strategy Reveals a Range of Aromatic Side Chain Motion in Calmodulin V Kasinath, KG Valentine, AJ Wand Journal of the American Chemical Society 135 (26), 9560-9563, 2013 | 61 | 2013 |
A sharp thermal transition of fast Aromatic‐Ring dynamics in ubiquitin V Kasinath, Y Fu, KA Sharp, AJ Wand Angewandte Chemie International Edition 54 (1), 102-107, 2015 | 32 | 2015 |
Structural basis for inactivation of PRC2 by G-quadruplex RNA J Song, AR Gooding, WO Hemphill, BD Love, A Robertson, L Yao, LI Zon, ... Science 381 (6664), 1331-1337, 2023 | 31 | 2023 |
Recent structural insights into polycomb repressive complex 2 regulation and substrate binding V Kasinath, S Poepsel, E Nogales Biochemistry 58 (5), 346-354, 2018 | 24 | 2018 |
Banding 2of NMR‐derived methyl order parameters: Implications for protein dynamics KA Sharp, V Kasinath, AJ Wand Proteins: Structure, Function, and Bioinformatics 82 (9), 2106-2117, 2014 | 24 | 2014 |
DNMT1 inhibition by pUG-fold quadruplex RNA LI Jansson-Fritzberg, CI Sousa, MJ Smallegan, JJ Song, AR Gooding, ... RNA 29 (3), 346-360, 2023 | 14 | 2023 |
Dynamic and thermodynamic response of the Ras protein Cdc42Hs upon association with the effector domain of PAK3 VR Moorman, KG Valentine, S Bédard, V Kasinath, J Dogan, FM Love, ... Journal of molecular biology 426 (21), 3520-3538, 2014 | 12 | 2014 |
JARID2 and AEBP2 regulate PRC2 activity in the presence of H2A ubiquitination or other histone modifications V Kasinath, C Beck, P Sauer, S Poepsel, J Kosmatka, M Faini, D Toso, ... BioRxiv, 2020.04. 20.049213, 2020 | 9 | 2020 |
Structural insights into the interactions of Polycomb Repressive Complex 2 with chromatin AG Iragavarapu, L Yao, V Kasinath Biochemical Society Transactions 49 (6), 2639-2653, 2021 | 4 | 2021 |
Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications T Cookis, A Lydecker, P Sauer, V Kasinath, E Nogales bioRxiv, 2024 | 1 | 2024 |
Visualization of PRC2-dinucleosome interactions leading to epigenetic repression S Poepsel, V Kasinath, E Nogales bioRxiv, 245134, 2018 | 1 | 2018 |
Diverse RNA Structures Induce PRC2 Dimerization and Inhibit Histone Methyltransferase Activity J Song, L Yao, AR Gooding, V Thron, V Kasinath, TR Cech bioRxiv, 2024.08. 29.610323, 2024 | | 2024 |