Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36 SF De Almeida, AR Grosso, F Koch, R Fenouil, S Carvalho, J Andrade, ... Nature structural & molecular biology 18 (9), 977-983, 2011 | 277 | 2011 |
SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint S Carvalho, AC Vítor, SC Sridhara, FB Martins, AC Raposo, JMP Desterro, ... elife 3, e02482, 2014 | 262 | 2014 |
Chemical chaperones reduce endoplasmic reticulum stress and prevent mutant HFE aggregate formation SF de Almeida, G Picarote, JV Fleming, M Carmo-Fonseca, JE Azevedo, ... Journal of Biological Chemistry 282 (38), 27905-27912, 2007 | 198 | 2007 |
Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription S Carvalho, AC Raposo, FB Martins, AR Grosso, SC Sridhara, J Rino, ... Nucleic acids research 41 (5), 2881-2893, 2013 | 190 | 2013 |
Studying DNA double-strand break repair: an ever-growing toolbox AC Vítor, P Huertas, G Legube, SRF De Almeida Frontiers in molecular biosciences 7, 24, 2020 | 165 | 2020 |
Introns protect eukaryotic genomes from transcription-associated genetic instability A Bonnet, AR Grosso, A Elkaoutari, E Coleno, A Presle, SC Sridhara, ... Molecular cell 67 (4), 608-621. e6, 2017 | 140 | 2017 |
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma AR Grosso, AP Leite, S Carvalho, MR Matos, FB Martins, AC Vítor, ... Elife 4, e09214, 2015 | 139 | 2015 |
ER stress-inducible factor CHOP affects the expression of hepcidin by modulating C/EBPalpha activity SJ Oliveira, JP Pinto, G Picarote, VM Costa, F Carvalho, M Rangel, ... PLoS One 4 (8), e6618, 2009 | 134 | 2009 |
Transcription dynamics prevent RNA-mediated genomic instability through SRPK2-dependent DDX23 phosphorylation SC Sridhara, S Carvalho, AR Grosso, LM Gallego-Paez, ... Cell reports 18 (2), 334-343, 2017 | 107 | 2017 |
Stimulation of an unfolded protein response impairs MHC class I expression SF de Almeida, JV Fleming, JE Azevedo, M Carmo-Fonseca, M de Sousa The Journal of Immunology 178 (6), 3612-3619, 2007 | 97 | 2007 |
Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3′ end of human genes SB Martins, J Rino, T Carvalho, C Carvalho, M Yoshida, JM Klose, ... Nature structural & molecular biology 18 (10), 1115-1123, 2011 | 92 | 2011 |
HFE cross-talks with the MHC class I antigen presentation pathway SF De Almeida, IF Carvalho, CS Cardoso, JV Cordeiro, JE Azevedo, ... Blood 106 (3), 971-977, 2005 | 80 | 2005 |
A link between nuclear RNA surveillance, the human exosome and RNA polymerase II transcriptional termination SF de Almeida, A García-Sacristán, N Custodio, M Carmo-Fonseca Nucleic acids research 38 (22), 8015-8026, 2010 | 78 | 2010 |
The CTD role in cotranscriptional RNA processing and surveillance SF de Almeida, M Carmo-Fonseca FEBS letters 582 (14), 1971-1976, 2008 | 71 | 2008 |
Design principles of interconnections between chromatin and pre-mRNA splicing SF De Almeida, M Carmo-Fonseca Trends in biochemical sciences 37 (6), 248-253, 2012 | 63 | 2012 |
Single-molecule imaging of transcription at damaged chromatin AC Vítor, SC Sridhara, JC Sabino, AI Afonso, AR Grosso, RM Martin, ... Science Advances 5 (1), eaau1249, 2019 | 58 | 2019 |
Dynamic transitions in RNA polymerase II density profiles during transcription termination AR Grosso, SF de Almeida, J Braga, M Carmo-Fonseca Genome Research 22 (8), 1447-1456, 2012 | 53 | 2012 |
Reciprocal regulatory links between cotranscriptional splicing and chromatin SF de Almeida, M Carmo-Fonseca Seminars in cell & developmental biology 32, 2-10, 2014 | 36 | 2014 |
T cell activation regulates CD6 alternative splicing by transcription dynamics and SRSF1 VG da Glória, M Martins de Araújo, A Mafalda Santos, R Leal, ... The Journal of Immunology 193 (1), 391-399, 2014 | 34 | 2014 |
TAL1/SCL is downregulated upon histone deacetylase inhibition in T-cell acute lymphoblastic leukemia cells BA Cardoso, SF De Almeida, ABA Laranjeira, M Carmo-Fonseca, ... Leukemia 25 (10), 1578-1586, 2011 | 32 | 2011 |