| A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes NA Thornberry, HG Bull, JR Calaycay, KT Chapman, AD Howard, ... Nature 356 (6372), 768-774, 1992 | 3506 | 1992 |
| A combinatorial approach defines specificities of members of the caspase family and granzyme B Functional relationships established for key mediators of apoptosis NA Thornberry, TA Rano, EP Peterson, DM Rasper, T Timkey, ... Journal of Biological Chemistry 272 (29), 17907-17911, 1997 | 2767 | 1997 |
| Directed reduction of. beta.-hydroxy ketones employing tetramethylammonium triacetoxyborohydride DA Evans, KT Chapman, EM Carreira Journal of the American Chemical Society 110 (11), 3560-3578, 1988 | 1399 | 1988 |
| The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1) M Garcia-Calvo, JM Lisnock, HG Bull, BE Hawes, DA Burnett, MP Braun, ... Proceedings of the National Academy of sciences 102 (23), 8132-8137, 2005 | 973 | 2005 |
| Asymmetric Diels-Alder cycloaddition reactions with chiral. alpha.,. beta.-unsaturated N-acyloxazolidinones DA Evans, KT Chapman, J Bisaha Journal of the American Chemical Society 110 (4), 1238-1256, 1988 | 939 | 1988 |
| Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry SP Rohrer, ET Birzin, RT Mosley, SC Berk, SM Hutchins, DM Shen, ... Science 282 (5389), 737-740, 1998 | 573 | 1998 |
| Inactivation of interleukin-1. beta. converting enzyme by peptide (acyloxy) methyl ketones NA Thornberry, EP Peterson, JJ Zhao, AD Howard, PR Griffin, ... Biochemistry 33 (13), 3934-3940, 1994 | 389 | 1994 |
| A combinatorial approach for determining protease specificities: application to interleukin-1β converting enzyme (ICE) TA Rano, T Timkey, EP Peterson, J Rotonda, DW Nicholson, JW Becker, ... Chemistry & biology 4 (2), 149-155, 1997 | 353 | 1997 |
| The directed reduction of β-hydroxy ketones employing Me4NHB (OAc) 3 DA Evans, KT Chapman Tetrahedron letters 27 (49), 5939-5942, 1986 | 282 | 1986 |
| New asymmetric Diels-Alder cycloaddition reactions. Chiral. alpha.,. beta.-unsaturated carboximides as practical chiral acrylate and crotonate dienophile synthons DA Evans, KT Chapman, J Bisaha Journal of the American Chemical Society 106 (15), 4261-4263, 1984 | 252 | 1984 |
| Convenient and inexpensive procedure for oxidation of secondary alcohols to ketones RV Stevens, KT Chapman, HN Weller The Journal of Organic Chemistry 45 (10), 2030-2032, 1980 | 237 | 1980 |
| Anthrax lethal factor inhibition WL Shoop, Y Xiong, J Wiltsie, A Woods, J Guo, JV Pivnichny, T Felcetto, ... Proceedings of the National Academy of Sciences 102 (22), 7958-7963, 2005 | 215 | 2005 |
| The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron … II Singer, S Scott, J Chin, EK Bayne, G Limjuco, J Weidner, DK Miller, ... The Journal of experimental medicine 182 (5), 1447-1459, 1995 | 195 | 1995 |
| Further studies on the utility of sodium hypochlorite in organic synthesis. Selective oxidation of diols and direct conversion of aldehydes to esters RV Stevens, KT Chapman, CA Stubbs, WW Tam, KF Albizati Tetrahedron Letters 23 (45), 4647-4650, 1982 | 182 | 1982 |
| Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2 L Yang, SC Berk, SP Rohrer, RT Mosley, L Guo, DJ Underwood, ... Proceedings of the National Academy of Sciences 95 (18), 10836-10841, 1998 | 176 | 1998 |
| Solid phase synthesis of aryl ethers via the Mitsunobu reaction TA Rano, KT Chapman Tetrahedron letters 36 (22), 3789-3792, 1995 | 169 | 1995 |
| Dendrimer-supported combinatorial chemistry RM Kim, M Manna, SM Hutchins, PR Griffin, NA Yates, AM Bernick, ... Proceedings of the National Academy of Sciences 93 (19), 10012-10017, 1996 | 151 | 1996 |
| Transition State π‐Solvation by Aromatic Rings: An Electronic Contribution to Diels–Alder Reaction Diastereoselectivity DA Evans, KT Chapman, DT Hung, AT Kawaguchi Angewandte Chemie International Edition in English 26 (11), 1184-1186, 1987 | 148 | 1987 |
| Fischer indole synthesis on a solid support SM Hutchins, KT Chapman Tetrahedron letters 37 (28), 4869-4872, 1996 | 133 | 1996 |
| Mimicry of erythropoietin by a nonpeptide molecule SA Qureshi, RM Kim, Z Konteatis, DE Biazzo, H Motamedi, R Rodrigues, ... Proceedings of the National Academy of Sciences 96 (21), 12156-12161, 1999 | 129 | 1999 |
