Biallelic variants in LIG3 cause a novel mitochondrial neurogastrointestinal encephalomyopathy E Bonora, S Chakrabarty, G Kellaris, M Tsutsumi, F Bianco, C Bergamini, ... Brain 144 (5), 1451-1466, 2021 | 38 | 2021 |
Coenzyme Q10 phytosome formulation improves CoQ10 bioavailability and mitochondrial functionality in cultured cells N Rizzardi, I Liparulo, G Antonelli, F Orsini, A Riva, C Bergamini, R Fato Antioxidants 10 (6), 927, 2021 | 23 | 2021 |
Coenzyme Q biosynthesis inhibition induces HIF‐1α stabilization and metabolic switch toward glycolysis I Liparulo, C Bergamini, M Bortolus, N Calonghi, G Gasparre, I Kurelac, ... The FEBS journal 288 (6), 1956-1974, 2021 | 22 | 2021 |
A novel mutation in SPART gene causes a severe neurodevelopmental delay due to mitochondrial dysfunction with complex I impairments and altered pyruvate metabolism C Diquigiovanni, C Bergamini, R Diaz, I Liparulo, F Bianco, L Masin, ... Faseb Journal, 2019 | 16 | 2019 |
BID and the α-bisabolol-triggered cell death program: Converging on mitochondria and lysosomes A Rigo, I Ferrarini, E Lorenzetto, E Darra, I Liparulo, C Bergamini, C Sissa, ... Cell Death & Disease 10 (12), 889, 2019 | 15 | 2019 |
Novel multi target-directed ligands targeting 5-HT4 receptors with in cellulo antioxidant properties as promising leads in Alzheimer's disease C Lanthier, H Payan, I Liparulo, B Hatat, C Lecoutey, M Since, A Davis, ... European Journal of Medicinal Chemistry 182, 111596, 2019 | 15 | 2019 |
Coenzyme Q depletion reshapes MCF-7 cells metabolism W Wang, I Liparulo, N Rizzardi, P Bolignano, N Calonghi, C Bergamini, ... International Journal of Molecular Sciences 22 (1), 198, 2020 | 14 | 2020 |
MiR-494 induces metabolic changes through G6pc targeting and modulates sorafenib response in hepatocellular carcinoma C Bergamini, I Leoni, N Rizzardi, M Melli, G Galvani, CA Coada, ... Journal of Experimental & Clinical Cancer Research 42 (1), 145, 2023 | 12 | 2023 |
Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties G de Andrade Ramos, AS de Oliveira, M Bartolini, M Naldi, I Liparulo, ... RSC Medicinal Chemistry 12 (7), 1154-1163, 2021 | 10 | 2021 |
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy N Southwell, G Primiano, V Nadkarni, N Attarwala, E Beattie, D Miller, ... EMBO Molecular Medicine 15 (7), e16951, 2023 | 8 | 2023 |
Insights into penicillin-induced Chlamydia trachomatis persistence C Foschi, M Bortolotti, L Polito, A Marangoni, C Zalambani, I Liparulo, ... Microbial pathogenesis 142, 104035, 2020 | 8 | 2020 |
CoQ regulates brown adipose tissue respiration and uncoupling protein 1 expression CF Chang, AL Gunawan, I Liparulo, PJH Zushin, AM Bertholet, Y Kirichok, ... Antioxidants 12 (1), 14, 2022 | 6 | 2022 |
Mutant SPART causes defects in mitochondrial protein import and bioenergetics reversed by Coenzyme Q C Diquigiovanni, N Rizzardi, A Kampmeier, I Liparulo, F Bianco, ... Open biology 13 (7), 230040, 2023 | 3 | 2023 |
Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis CF Chang, AL Gunawan, I Liparulo, PJH Zushin, K Vitangcol, GA Timblin, ... The EMBO Journal 43 (2), 168-195, 2024 | 2 | 2024 |
MiR-494 induces metabolic reprogramming through G6pc targeting and modulates sorafenib response in hepatocellular carcinoma G Galvani, I Leoni, C Bergamini, N Rizzardi, M Melli, CA Coada, E Monti, ... Digestive and Liver Disease 55, S47, 2023 | | 2023 |
Biallelic variants in SPART cause a mitochondrial dysfunction and cell cycle arrest in Troyer Syndrome C Diquigiovanni, A Kampmeier, E Cuna, N Rizzardi, I Liparulo, F Bianco, ... EUROPEAN JOURNAL OF HUMAN GENETICS 30 (SUPPL 1), 207-208, 2022 | | 2022 |
Convergent bioenergetic defects in Coenzyme Q10 depleted cells by pharmacological inhibition of coq2 enzyme (p-hydroxybenzoate polyprenyl transferase) and by genome editing … I Liparulo alma, 2021 | | 2021 |
Mutations in LIG3 are a novel cause of mitochondrial neurogastrointestinal encephalomyopathy E Bonora, F Bianco, C Bergamini, G Kellaris, F Ullah, F Isidori, I Liparulo, ... EUROPEAN JOURNAL OF HUMAN GENETICS 27, 1159-1160, 2019 | | 2019 |
In Troyer syndrome Spartin loss induces Complex I impairments and alters pyruvate metabolism C Diquigiovanni, C Bergamini, R Diaz, I Liparulo, F Bianco, L Masin, ... bioRxiv, 488239, 2018 | | 2018 |
Coenzyme Q10 depletion induces endogenous hypoxia in cultured cells I Liparulo, C Bergamini, W Wang, L Masin, N Rizzardi, I Kurelac, ... BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1859, e15-1, 2018 | | 2018 |