Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ... Nature genetics 50 (5), 668-681, 2018 | 2603 | 2018 |
Genome-wide association study identifies 30 loci associated with bipolar disorder EA Stahl, G Breen, AJ Forstner, A McQuillin, S Ripke, V Trubetskoy, ... Nature genetics 51 (5), 793-803, 2019 | 1404 | 2019 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 1061 | 2019 |
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa HJ Watson, Z Yilmaz, LM Thornton, C Hübel, JRI Coleman, HA Gaspar, ... Nature genetics 51 (8), 1207-1214, 2019 | 834 | 2019 |
Genetic identification of brain cell types underlying schizophrenia NG Skene, J Bryois, TE Bakken, G Breen, JJ Crowley, HA Gaspar, ... Nature genetics 50 (6), 825-833, 2018 | 550 | 2018 |
Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes DM Ruderfer, S Ripke, A McQuillin, J Boocock, EA Stahl, JMW Pavlides, ... Cell 173 (7), 1705-1715. e16, 2018 | 527 | 2018 |
Comparative genetic architectures of schizophrenia in East Asian and European populations M Lam, CY Chen, Z Li, AR Martin, J Bryois, X Ma, H Gaspar, M Ikeda, ... Nature genetics 51 (12), 1670-1678, 2019 | 524 | 2019 |
Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa L Duncan, Z Yilmaz, H Gaspar, R Walters, J Goldstein, V Anttila, ... American journal of psychiatry 174 (9), 850-858, 2017 | 482 | 2017 |
A major role for common genetic variation in anxiety disorders KL Purves, JRI Coleman, SM Meier, C Rayner, KAS Davis, R Cheesman, ... Molecular psychiatry 25 (12), 3292-3303, 2020 | 305 | 2020 |
Generative topographic mapping (GTM): universal tool for data visualization, structure‐activity modeling and dataset comparison N Kireeva, II Baskin, HA Gaspar, D Horvath, G Marcou, A Varnek Molecular informatics 31 (3‐4), 301-312, 2012 | 157 | 2012 |
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank JRI Coleman, WJ Peyrot, KL Purves, KAS Davis, C Rayner, SW Choi, ... Molecular psychiatry 25 (7), 1430-1446, 2020 | 156 | 2020 |
Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors N Mullins, JE Kang, AI Campos, JRI Coleman, AC Edwards, H Galfalvy, ... Biological psychiatry 91 (3), 313-327, 2022 | 147 | 2022 |
The genetics of the mood disorder spectrum: genome-wide association analyses of more than 185,000 cases and 439,000 controls JRI Coleman, HA Gaspar, J Bryois, EM Byrne, AJ Forstner, PA Holmans, ... Biological psychiatry 88 (2), 169-184, 2020 | 146 | 2020 |
A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts G Ni, J Zeng, JA Revez, Y Wang, Z Zheng, T Ge, R Restuadi, J Kiewa, ... Biological psychiatry 90 (9), 611-620, 2021 | 142 | 2021 |
Translating genome-wide association findings into new therapeutics for psychiatry G Breen, Q Li, BL Roth, P O'donnell, M Didriksen, R Dolmetsch, PF O'reilly, ... Nature neuroscience 19 (11), 1392-1396, 2016 | 142 | 2016 |
Evaluation of polygenic prediction methodology within a reference-standardized framework O Pain, KP Glanville, SP Hagenaars, S Selzam, AE Fürtjes, HA Gaspar, ... PLoS genetics 17 (5), e1009021, 2021 | 126 | 2021 |
Molecular representation learning with language models and domain-relevant auxiliary tasks B Fabian, T Edlich, H Gaspar, M Segler, J Meyers, M Fiscato, M Ahmed arXiv preprint arXiv:2011.13230, 2020 | 125 | 2020 |
Does childhood trauma moderate polygenic risk for depression? A meta-analysis of 5765 subjects from the psychiatric genomics consortium WJ Peyrot, S Van der Auwera, Y Milaneschi, CV Dolan, PAF Madden, ... Biological psychiatry 84 (2), 138-147, 2018 | 119 | 2018 |
The genetic architecture of depression in individuals of East Asian ancestry: a genome-wide association study O Giannakopoulou, K Lin, X Meng, MH Su, PH Kuo, RE Peterson, ... JAMA psychiatry 78 (11), 1258-1269, 2021 | 114 | 2021 |
eQTLGen; 23andMe; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Genome-wide association analyses identify 44 risk variants and refine the … NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ... Nat Genet 50 (5), 668-681, 2018 | 114 | 2018 |