OptiType: precision HLA typing from next-generation sequencing data A Szolek, B Schubert, C Mohr, M Sturm, M Feldhahn, O Kohlbacher Bioinformatics 30 (23), 3310-3316, 2014 | 689 | 2014 |
Best practices for single-cell analysis across modalities L Heumos, AC Schaar, C Lance, A Litinetskaya, F Drost, L Zappia, ... Nature Reviews Genetics 24 (8), 550-572, 2023 | 345 | 2023 |
The EVcouplings Python framework for coevolutionary sequence analysis TA Hopf, AG Green, B Schubert, S Mersmann, CPI Schärfe, JB Ingraham, ... Bioinformatics 35 (9), 1582-1584, 2019 | 225 | 2019 |
scCODA is a Bayesian model for compositional single-cell data analysis M Buettner, J Ostner, CL Mueller, FJ Theis, B Schubert Nature communications 12 (1), 6876, 2021 | 159 | 2021 |
Induction of neoantigen-reactive T cells from healthy donors M Ali, Z Foldvari, E Giannakopoulou, ML Böschen, E Strønen, W Yang, ... Nature protocols 14 (6), 1926-1943, 2019 | 118 | 2019 |
Predicting antigen specificity of single T cells based on TCR CDR 3 regions DS Fischer, Y Wu, B Schubert, FJ Theis Molecular systems biology 16 (8), e9416, 2020 | 97 | 2020 |
Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19 R Kaiser, A Leunig, K Pekayvaz, O Popp, M Joppich, V Polewka, R Escaig, ... JCI insight 6 (18), 2021 | 94 | 2021 |
Artificial intelligence in early drug discovery enabling precision medicine F Boniolo, E Dorigatti, AJ Ohnmacht, D Saur, B Schubert, MP Menden Expert Opinion on Drug Discovery 16 (9), 991-1007, 2021 | 84 | 2021 |
Impaired function and delayed regeneration of dendritic cells in COVID-19 E Winheim, L Rinke, K Lutz, A Reischer, A Leutbecher, L Wolfram, ... PLoS pathogens 17 (10), e1009742, 2021 | 82 | 2021 |
Designing string-of-beads vaccines with optimal spacers B Schubert, O Kohlbacher Genome medicine 8, 1-10, 2016 | 54 | 2016 |
Genome-wide discovery of epistatic loci affecting antibiotic resistance in Neisseria gonorrhoeae using evolutionary couplings B Schubert, R Maddamsetti, J Nyman, MR Farhat, DS Marks Nature Microbiology 4 (2), 328-338, 2019 | 43 | 2019 |
EpiToolKit—a web-based workbench for vaccine design B Schubert, HP Brachvogel, C Jürges, O Kohlbacher Bioinformatics 31 (13), 2211-2213, 2015 | 42 | 2015 |
FRED 2: an immunoinformatics framework for Python B Schubert, M Walzer, HP Brachvogel, A Szolek, C Mohr, O Kohlbacher Bioinformatics 32 (13), 2044-2046, 2016 | 38 | 2016 |
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’ DS Fischer, M Ansari, KI Wagner, S Jarosch, Y Huang, CH Mayr, M Strunz, ... Nature communications 12 (1), 4515, 2021 | 33 | 2021 |
Evaluation of peptide selection approaches for epitope‐based vaccine design B Schubert, O Lund, M Nielsen Tissue Antigens 82 (4), 243-251, 2013 | 33 | 2013 |
An unusually high substitution rate in transplant-associated BK polyomavirus in vivo is further concentrated in HLA-C-bound viral peptides P Domingo-Calap, B Schubert, M Joly, M Solis, M Untrau, R Carapito, ... PLoS pathogens 14 (10), e1007368, 2018 | 28 | 2018 |
Population-specific design of de-immunized protein biotherapeutics B Schubert, C Schärfe, P Dönnes, T Hopf, D Marks, O Kohlbacher PLoS computational biology 14 (3), e1005983, 2018 | 23 | 2018 |
ClinOmicsTrailbc: a visual analytics tool for breast cancer treatment stratification L Schneider, T Kehl, K Thedinga, NL Grammes, C Backes, C Mohr, ... Bioinformatics 35 (24), 5171-5181, 2019 | 21 | 2019 |
Antigen-specific treg therapy in type 1 diabetes–challenges and opportunities I Serr, F Drost, B Schubert, C Daniel Frontiers in immunology 12, 712870, 2021 | 16 | 2021 |
ImmunoNodes–graphical development of complex immunoinformatics workflows B Schubert, L de la Garza, C Mohr, M Walzer, O Kohlbacher BMC bioinformatics 18, 1-7, 2017 | 13 | 2017 |