| Advances and challenges in computational target prediction D Sydow, L Burggraaff, A Szengel, HWT van Vlijmen, AP IJzerman, ... Journal of chemical information and modeling 59 (5), 1728-1742, 2019 | 102 | 2019 |
| Activity-based protein profiling identifies α-ketoamides as inhibitors for phospholipase A2 group XVI J Zhou, ED Mock, A Martella, V Kantae, X Di, L Burggraaff, MP Baggelaar, ... ACS Chemical Biology 14 (2), 164-169, 2019 | 31 | 2019 |
| Identification of novel small molecule inhibitors for solute carrier SGLT1 using proteochemometric modeling L Burggraaff, P Oranje, R Gouka, P van der Pijl, M Geldof, ... Journal of cheminformatics 11, 1-10, 2019 | 26 | 2019 |
| Development of ubiquitin‐based probe for metalloprotease deubiquitinases DS Hameed, A Sapmaz, L Burggraaff, A Amore, CJ Slingerland, ... Angewandte Chemie International Edition 58 (41), 14477-14482, 2019 | 25 | 2019 |
| Rapid screening and identification of ACE inhibitors in snake venoms using at-line nanofractionation LC-MS M Mladic, T de Waal, L Burggraaff, J Slagboom, GW Somsen, ... Analytical and bioanalytical chemistry 409, 5987-5997, 2017 | 24 | 2017 |
| Novel natural and synthetic inhibitors of solute carriers SGLT1 and SGLT2 P Oranje, R Gouka, L Burggraaff, M Vermeer, C Chalet, G Duchateau, ... Pharmacology Research & Perspectives 7 (4), e00504, 2019 | 22 | 2019 |
| Development of a retinal-based probe for the profiling of retinaldehyde dehydrogenases in cancer cells STA Koenders, LS Wijaya, MN Erkelens, AT Bakker, VE van der Noord, ... ACS central science 5 (12), 1965-1974, 2019 | 17 | 2019 |
| Quantitative prediction of selectivity between the A1 and A2A adenosine receptors L Burggraaff, HWT van Vlijmen, AP IJzerman, GJP van Westen Journal of Cheminformatics 12, 1-16, 2020 | 15 | 2020 |
| Design and pharmacological profile of a novel covalent partial agonist for the adenosine A1 receptor X Yang, MA Dilweg, D Osemwengie, L Burggraaff, D van der Es, ... Biochemical Pharmacology 180, 114144, 2020 | 15 | 2020 |
| Structure–activity relationship studies of α-ketoamides as inhibitors of the phospholipase A and acyltransferase enzyme family J Zhou, ED Mock, K Al Ayed, X Di, V Kantae, L Burggraaff, AF Stevens, ... Journal of Medicinal Chemistry 63 (17), 9340-9359, 2020 | 12 | 2020 |
| Identification of novel small molecule inhibitors for solute carrier SGLT1 using proteochemometric modeling. J Cheminform 11: 15 L Burggraaff, P Oranje, R Gouka, P Van Der Pijl, M Geldof, ... | 7 | 2019 |
| Successive statistical and structure-based modeling to identify chemically novel kinase inhibitors L Burggraaff, EB Lenselink, W Jespers, J van Engelen, BJ Bongers, ... Journal of Chemical Information and Modeling 60 (9), 4283-4295, 2020 | 6 | 2020 |
| Annotation of allosteric compounds to enhance bioactivity modeling for class a GPCRs L Burggraaff, A van Veen, CC Lam, HWT van Vlijmen, AP IJzerman, ... Journal of Chemical Information and Modeling 60 (10), 4664-4672, 2020 | 4 | 2020 |
| A multiple classifier system identifies novel cannabinoid CB2 receptor ligands D Ruano-Ordás, L Burggraaff, R Liu, C van der Horst, LH Heitman, ... Journal of Cheminformatics 11, 1-14, 2019 | 4 | 2019 |
| Synthesis and SAR evaluation of coumarin derivatives as potent cannabinoid receptor agonists F Mohr, T Hurrle, L Burggraaff, L Langer, MP Bemelmans, M Knab, ... European Journal of Medicinal Chemistry 220, 113354, 2021 | 2 | 2021 |
| Proteins in harmony: Tuning selectivity in early drug discovery L Burggraaff Leiden University, 2020 | | 2020 |
| Design, Synthesis and Pharmacological Profile of LUF7746, a Novel Covalent Partial Agonist for the Adenosine A1 Receptor X Yang, M Dilweg, D Osemwengie, L Burggraaff, D van der Es, L Heitman, ... | | 2020 |
| Quantitative prediction of selectivity between the A L Burggraaff, HWT van Vlijmen, AP IJzerman, GJP van Westen | | 2020 |
| Chapter two Advances and Challenges in Computational Target Prediction D Sydow, L Burggraaff, A Szengel, HWT van Vlijmen, AP IJzerman, ... Proteins in Harmony Tuning Selectivity in Early Drug Discovery, 21, 0 | | |
| Chapter three Identification of Novel Small Molecule Inhibitors for Solute Carrier SGLT1 using Proteochemometric Modeling L Burggraaff, P Oranje, R Gouka, P van der Pijl, M Geldof, H WT Proteins in Harmony Tuning Selectivity in Early Drug Discovery, 49, 0 | | |
