Pulsatile stimulation determines timing and specificity of NF-κB-dependent transcription L Ashall, CA Horton, DE Nelson, P Paszek, CV Harper, K Sillitoe, S Ryan, ... Science 324 (5924), 242-246, 2009 | 664 | 2009 |
Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models MJD Daniels, J Rivers-Auty, T Schilling, NG Spencer, W Watremez, ... Nature communications 7 (1), 12504, 2016 | 417 | 2016 |
Mathematical model of NF-κB regulatory module T Lipniacki, P Paszek, AR Brasier, B Luxon, M Kimmel Journal of theoretical biology 228 (2), 195-215, 2004 | 394 | 2004 |
Inflammasome-dependent IL-1β release depends upon membrane permeabilisation F Martín-Sánchez, C Diamond, M Zeitler, AI Gomez, A Baroja-Mazo, ... Cell Death & Differentiation 23 (7), 1219-1231, 2016 | 276 | 2016 |
Population robustness arising from cellular heterogeneity P Paszek, S Ryan, L Ashall, K Sillitoe, CV Harper, DG Spiller, DA Rand, ... Proceedings of the National Academy of Sciences 107 (25), 11644-11649, 2010 | 225 | 2010 |
Physiological levels of TNFα stimulation induce stochastic dynamics of NF-κB responses in single living cells DA Turner, P Paszek, DJ Woodcock, DE Nelson, CA Horton, Y Wang, ... Journal of cell science 123 (16), 2834-2843, 2010 | 165 | 2010 |
Transcriptional stochasticity in gene expression T Lipniacki, P Paszek, A Marciniak-Czochra, AR Brasier, M Kimmel Journal of theoretical biology 238 (2), 348-367, 2006 | 157 | 2006 |
Stochastic regulation in early immune response T Lipniacki, P Paszek, AR Brasier, BA Luxon, M Kimmel Biophysical journal 90 (3), 725-742, 2006 | 133 | 2006 |
Single TNFα trimers mediating NF-κ B activation: stochastic robustness of NF-κ B signaling T Lipniacki, K Puszynski, P Paszek, AR Brasier, M Kimmel BMC bioinformatics 8, 1-20, 2007 | 100 | 2007 |
Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states A Adamson, C Boddington, P Downton, W Rowe, J Bagnall, C Lam, ... Nature communications 7 (1), 12057, 2016 | 82 | 2016 |
Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation JM Ankers, R Awais, NA Jones, J Boyd, S Ryan, AD Adamson, CV Harper, ... Elife 5, e10473, 2016 | 62 | 2016 |
Integration of kinase and calcium signaling at the level of chromatin underlies inducible gene activation in T cells R Brignall, P Cauchy, SL Bevington, B Gorman, AO Pisco, J Bagnall, ... The Journal of Immunology 199 (8), 2652-2667, 2017 | 61 | 2017 |
Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation J Bagnall, C Boddington, H England, R Brignall, P Downton, Z Alsoufi, ... Science signaling 11 (540), eaaf3998, 2018 | 57 | 2018 |
Dynamic organisation of prolactin gene expression in living pituitary tissue CV Harper, K Featherstone, S Semprini, S Friedrichsen, J McNeilly, ... Journal of Cell Science 123 (3), 424-430, 2010 | 54 | 2010 |
Oscillatory control of signalling molecules P Paszek, DA Jackson, MRH White Current opinion in genetics & development 20 (6), 670-676, 2010 | 53 | 2010 |
Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation NE Phillips, CS Manning, T Pettini, V Biga, E Marinopoulou, P Stanley, ... Elife 5, e16118, 2016 | 50 | 2016 |
Interactions among oscillatory pathways in NF-kappa B signaling Y Wang, P Paszek, CA Horton, DB Kell, MRH White, DS Broomhead, ... BMC systems biology 5, 1-11, 2011 | 47 | 2011 |
Modeling stochasticity in gene regulation: characterization in the terms of the underlying distribution function P Paszek Bulletin of Mathematical Biology 69, 1567-1601, 2007 | 45 | 2007 |
Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer J Bagnall, C Boddington, J Boyd, R Brignall, W Rowe, NA Jones, ... Integrative Biology 7 (6), 713-725, 2015 | 42 | 2015 |
Anti-inflammatory effects of infliximab in mice are independent of tumour necrosis factor α neutralization BM Assas, SE Levison, M Little, H England, L Battrick, J Bagnall, ... Clinical & Experimental Immunology 187 (2), 225-233, 2017 | 40 | 2017 |