| Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases MTN Yarnall, EI Ioannidi, C Schmitt-Ulms, RN Krajeski, J Lim, L Villiger, ... Nature Biotechnology 41 (4), 500-512, 2023 | 250 | 2023 |
| Extensive double humanization of both liver and hematopoiesis in FRGN mice EM Wilson, J Bial, B Tarlow, G Bial, B Jensen, DL Greiner, MA Brehm, ... Stem cell research 13 (3), 404-412, 2014 | 148 | 2014 |
| Brain integrity is altered by hepatic APOE ε4 in humanized-liver mice A Giannisis, K Patra, AK Edlund, LA Nieto, J Benedicto-Gras, S Moussaud, ... Molecular Psychiatry 27 (8), 3533-3543, 2022 | 30 | 2022 |
| Consumptive coagulopathy of severe yellow fever occurs independently of hepatocellular tropism and massive hepatic injury AL Bailey, LI Kang, LGF de Assis Barros D’Elia Zanella, CGT Silveira, ... Proceedings of the National Academy of Sciences 117 (51), 32648-32656, 2020 | 24 | 2020 |
| Behavioral and cognitive performance of humanized APOEε3/ε3 liver mice in relation to plasma apolipoprotein E levels K Kessler, A Giannisis, G Bial, L Foquet, HM Nielsen, J Raber Scientific Reports 13 (1), 1728, 2023 | 4 | 2023 |
| Identifying novel mechanisms of per-and polyfluoroalkyl substance-induced hepatotoxicity using FRG humanized mice DR Robarts, D Paine-Cabrera, M Kotulkar, KK Venneman, ... Archives of Toxicology, 1-13, 2024 | 1 | 2024 |
| Identifying Human Specific Adverse Outcome Pathways of Per-and Polyfluoroalkyl Substances Using Liver-Chimeric Humanized Mice DR Robarts, D Paine-Cabrera, M Kotulkar, KK Venneman, ... bioRxiv, 2023 | 1 | 2023 |
| Impact of high-fat diet on brain integrity in APOEε3 humanized liver mice AK Edlund, A Giannisis, K Patra, THJ Morrema, G Bial, L Foquet, ... | | 2023 |
| Elucidating the effects of a high fat diet on markers of brain insulin signaling, gliosis and synaptic integrity in mice with humanized APOEε3 A Edlund, A Giannisis, K Patra, THJ Morrema, G Bial, L Foquet, ... | | 2021 |
| Effects of a high‐fat diet on the brain in FRGN mice with humanized livers: Molecular and cell biology/signal transduction AK Edlund, A Giannisis, K Patra, THJ Morrema, JJM Hoozemans, G Bial, ... Alzheimer's & Dementia 16, e046198, 2020 | | 2020 |
| Effects of a liver APOEε4‐genotype on synaptic integrity, gliosis and insulin signaling in the brain: Molecular and cell biology/synaptic disruption A Giannisis, K Patra, AK Edlund, ADL Rosa, LA Nieto, JB Gras, ... Alzheimer's & Dementia 16, e042463, 2020 | | 2020 |
| OF MICE AND MONKEYS: GENERATING MICE REPOPULATED WITH NON-HUMAN PRIMATE HEPATOCYTES AS A PREDICTIVE SMALL ANIMAL MODEL L Foquet, G Bial, M Grompe, R Copenhaver The Liver Meeting Digital Experience™, 2020 | | 2020 |
| Customized xenograft model development: liver repopulation of FRG® KO mice with primary hepatocytes from donors carrying specific genetic variants G Bial, L Foquet, M Grompe, R Copenhaver Journal of Hepatology 73, S548, 2020 | | 2020 |
| EFFECTS OF A LIVER APOEε4-GENOTYPE ON SYNAPTIC INTEGRITY, GLIOSIS AND INSULIN SIGNALING IN THE BRAIN A Giannisis, K Patra, AK Edlund, A De La Rosa, LA Nieto, JB Gras, ... 2020 Alzheimer's Association International Conference, 2020 | | 2020 |
| Effects of a high-fat diet on the brain in FRGN mice with humanized livers AK Edlund, A Giannisis, K Patra, THJ Morrema, JJM Hoozemans, G Bial, ... 2020 Alzheimer's Association International Conference, 2020 | | 2020 |
| Customized Xenograft Model Development: Liver Repopulation of FRG KO Mice with Primary Murine, NHP, or Human Hepatocytes L Foquet, G Bial, M Grompe, R Copenhaver MOLECULAR THERAPY 28 (4), 85-85, 2020 | | 2020 |
| EFFICACY OF LIVER REPOPULATION OF FRG MICE WITH PRIMARY HEPATOCYTES FROM DIFFERENT SPECIES OR HUMAN DONORS G Bial, L Foquet, M Grompe, R Copenhaver HEPATOLOGY 70, 445A-446A, 2019 | | 2019 |
