Molecular signatures of neuroinflammation induced by αsynuclein aggregates in microglial cells S Sarkar, EB Dammer, E Malovic, AL Olsen, SA Raza, T Gao, H Xiao, ... Frontiers in immunology 11, 33, 2020 | 78 | 2020 |
Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations M Huang, E Modeste, E Dammer, P Merino, G Taylor, DM Duong, Q Deng, ... Acta neuropathologica communications 8, 1-25, 2020 | 75 | 2020 |
Deletion of neuronal CuZnSOD accelerates age-associated muscle mitochondria and calcium handling dysfunction that is independent of denervation and precedes sarcopenia Y Su, DR Claflin, M Huang, CS Davis, PCD Macpherson, A Richardson, ... International Journal of Molecular Sciences 22 (19), 10735, 2021 | 15 | 2021 |
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer’s disease mouse model C Tallon, BJ Bell, MM Malvankar, P Deme, C Nogueras-Ortiz, E Eren, ... Translational Neurodegeneration 12 (1), 56, 2023 | 8 | 2023 |
Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice M Huang, C Tallon, X Zhu, KDJ Huizar, S Picciolini, AG Thomas, L Tenora, ... Pharmaceutics 15 (9), 2364, 2023 | 2 | 2023 |
GCPII Inhibition Promotes Remyelination after Peripheral Nerve Injury in Aged Mice Y Su, M Huang, AG Thomas, J Maragakis, KDJ Huizar, Y Zheng, Y Wu, ... International journal of molecular sciences 25 (13), 6893, 2024 | 1 | 2024 |
Microglial‐targeted nSMase2 inhibitor fails to reduce tau spread in the animal model of Alzheimer’s disease M Huang, C Tallon, X Zhu, K Huizar, S Piccirillo, AG Thomas, L Tenora, ... Alzheimer's & Dementia 20, e091930, 2024 | | 2024 |
Dectin-1 as a therapeutic target for inflammatory bowel disease Y Li, M Huang, S Cardinale, Y Su, DE Peters, BS Slusher, X Zhu Advances in pharmacology (San Diego, Calif.) 101, 237, 2024 | | 2024 |
Drug Development LPR: Drug discovery for Alzheimer's disease and related dementias JL Dage, M Huang Alzheimer's Association International Conference, 2024 | | 2024 |
GCPII Inhibition in Macrophages Delays Age-related Muscle Atrophy in Mice Y Su, C Tallon, A Thomas, K Huizar, M Huang, L Tenora, W Liyanage, ... Physiology 39 (S1), 2379, 2024 | | 2024 |
Neutral sphingomyelinase 2: A promising drug target for CNS disease M Huang, M Stremlau, J Zavras, C Zivko, AG Thomas, P Pietri, ... Advances in Pharmacology, 2024 | | 2024 |
Inhibition of EV biogenesis reduces tau propagation in Alzheimer’s Disease mouse models M Huang, C Tallon, BJ Bell, D Kapogiannis, NJ Haughey, R Rais, ... Alzheimer's & Dementia 19, e078341, 2023 | | 2023 |
Preclinical therapeutic targets and early phase studies TD Prevot, M Huang Alzheimer's Association International Conference, 2023 | | 2023 |
Network analysis of the brain proteome of GRN knockout mice reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations: Developing topics T Kukar, M Huang, ES Modeste, EB Dammer, CJ Holler, Q Deng, ... Alzheimer's & Dementia 16, e047569, 2020 | | 2020 |
Network Analysis of the Brain Proteome of Grn Knockout Mice Reveals Pathogenic Mechanisms Shared in Human Frontotemporal dementia caused by GRN mutations. M Huang The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |