Interleukin-22 protects intestinal stem cells against genotoxic stress K Gronke, PP Hernández, J Zimmermann, CSN Klose, M Kofoed-Branzk, ... Nature 566 (7743), 249-253, 2019 | 303 | 2019 |
Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide A Gulbins, F Schumacher, KA Becker, B Wilker, M Soddemann, F Boldrin, ... Molecular Psychiatry 23 (12), 2324-2346, 2018 | 194 | 2018 |
The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming SM Hochrein, H Wu, M Eckstein, L Arrigoni, JS Herman, F Schumacher, ... Cell Metabolism 34 (4), 516-532.e11, 2022 | 101 | 2022 |
Formulation and ex vivo evaluation of polymeric nanoparticles for controlled delivery of corticosteroids to the skin and the corneal epithelium B Balzus, FF Sahle, S Hönzke, C Gerecke, F Schumacher, S Hedtrich, ... European Journal of Pharmaceutics and Biopharmaceutics 115, 122-130, 2017 | 91 | 2017 |
Methionine restriction prevents onset of type 2 diabetes in NZO mice T Castaño-Martinez, F Schumacher, S Schumacher, B Kochlik, D Weber, ... The FASEB Journal 33 (6), 7092-7102, 2019 | 82 | 2019 |
Biocompatibility and characterization of polyglycerol-based thermoresponsive nanogels designed as novel drug delivery systems and their intracellular localization in keratinocytes C Gerecke, A Edlich, M Giulbudagian, F Schumacher, N Zhang, A Said, ... Nanotoxicology 11 (2), 267-277, 2017 | 72 | 2017 |
Ethyl cellulose nanocarriers and nanocrystals differentially deliver dexamethasone into intact, tape-stripped or sodium lauryl sulfate-exposed ex vivo human skin-assessment by … N Döge, S Hönzke, F Schumacher, B Balzus, M Colombo, S Hadam, ... Journal of Controlled Release 242, 25–34, 2016 | 72 | 2016 |
Monitoring the sphingolipid de novo synthesis by stable-isotope labeling and liquid chromatography-mass spectrometry D Wigger, E Gulbins, B Kleuser, F Schumacher Frontiers in Cell and Developmental Biology 7, 210, 2019 | 66 | 2019 |
Simultaneous Detection of Multiple DNA Adducts in Human Lung Samples by Isotope-Dilution UPLC-MS/MS BH Monien, F Schumacher, K Herrmann, H Glatt, RJ Turesky, C Chesné Analytical chemistry 87 (1), 641–648, 2015 | 66 | 2015 |
Enhanced acid sphingomyelinase activity drives immune evasion and tumor growth in non-small cell lung carcinoma K Kachler, M Bailer, L Heim, F Schumacher, M Reichel, C Holzinger, ... Cancer Research 77 (21), 5963-5976, 2017 | 60 | 2017 |
Abundance of DNA adducts of methyleugenol, a rodent hepatocarcinogen, in human liver samples K Herrmann, F Schumacher, W Engst, KE Appel, K Klein, UM Zanger, ... Carcinogenesis 34 (5), 1025-1030, 2013 | 59 | 2013 |
Enhanced Topical Delivery of Dexamethasone by beta-Cyclodextrin Decorated Thermoresponsive Nanogels M Giulbudagian, S Hönzke, JB Álvarez, D Isik, F Schumacher, ... Nanoscale 10 (1), 469-479, 2018 | 58 | 2018 |
Selenium increases hepatic DNA methylation and modulates one-carbon metabolism in the liver of mice B Speckmann, S Schulz, F Hiller, D Hesse, F Schumacher, B Kleuser, ... The Journal of Nutritional Biochemistry 48, 112-119, 2017 | 56 | 2017 |
Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase in vitro E Naser, S Kadow, F Schumacher, ZH Mohamed, C Kappe, G Hessler, ... Journal of Lipid Research 61 (6), 896-910, 2020 | 52 | 2020 |
Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake C Hausmann, C Zoschke, C Wolff, ME Darvin, M Sochorová, A Kováčik, ... Scientific reports 9 (1), 2913, 2019 | 49 | 2019 |
1-Methoxy-3-indolylmethyl glucosinolate; a potent genotoxicant in bacterial and mammalian cells: Mechanisms of bioactivation H Glatt, C Baasanjav-Gerber, F Schumacher, BH Monien, M Schreiner, ... Chemico-biological interactions 192 (1-2), 81-86, 2011 | 49 | 2011 |
Identification of functional lipid metabolism biomarkers of brown adipose tissue aging S Gohlke, V Zagoriy, AC Inostroza, M Méret, C Mancini, L Japtok, ... Molecular metabolism 24, 1–17, 2019 | 48 | 2019 |
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease J Lang, P Bohn, H Bhat, H Jastrow, B Walkenfort, F Cansiz, J Fink, ... Nature communications 11 (1), 1338, 2020 | 45 | 2020 |
Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor CDKN1A in colon cancer … C Gerecke, F Schumacher, A Edlich, A Wetzel, G Yealland, LK Neubert, ... Oncotarget 9 (67), 32822-32840, 2018 | 45 | 2018 |
Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation K Schwerbel, A Kamitz, N Krahmer, N Hallahan, M Jähnert, P Gottmann, ... Journal of Hepatology 73 (4), 771-782, 2020 | 39 | 2020 |