Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity F Borges, F Roleira, N Milhazes, L Santana, E Uriarte Current medicinal chemistry 12 (8), 887-916, 2005 | 1222 | 2005 |
Phenolic acid derivatives with potential anticancer properties––a structure–activity relationship study. Part 1: Methyl, propyl and octyl esters of caffeic and gallic acids SM Fiuza, C Gomes, LJ Teixeira, MTG Da Cruz, M Cordeiro, N Milhazes, ... Bioorganic & medicinal chemistry 12 (13), 3581-3589, 2004 | 388 | 2004 |
Anticancer activity of phenolic acids of natural or synthetic origin: a structure− activity study CA Gomes, T Girão da Cruz, JL Andrade, N Milhazes, F Borges, ... Journal of medicinal chemistry 46 (25), 5395-5401, 2003 | 322 | 2003 |
Chromone as a privileged scaffold in drug discovery: recent advances: miniperspective J Reis, A Gaspar, N Milhazes, F Borges Journal of medicinal chemistry 60 (19), 7941-7957, 2017 | 318 | 2017 |
Furocoumarins in medicinal chemistry. Synthesis, natural occurrence and biological activity L Santana, E Uriarte, F Roleira, N Milhazes, F Borges Current medicinal chemistry 11 (24), 3239-3261, 2004 | 231 | 2004 |
Methamphetamine‐induced neuroinflammation and neuronal dysfunction in the mice hippocampus: preventive effect of indomethacin J Gonçalves, S Baptista, T Martins, N Milhazes, F Borges, CF Ribeiro, ... European Journal of Neuroscience 31 (2), 315-326, 2010 | 160 | 2010 |
Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells TL Serafim, FS Carvalho, MPM Marques, R Calheiros, T Silva, J Garrido, ... Chemical research in toxicology 24 (5), 763-774, 2011 | 146 | 2011 |
Methamphetamine transiently increases the blood–brain barrier permeability in the hippocampus: role of tight junction proteins and matrix metalloproteinase-9 T Martins, S Baptista, J Gonçalves, E Leal, N Milhazes, F Borges, ... Brain research 1411, 28-40, 2011 | 143 | 2011 |
Simple coumarins: privileged scaffolds in medicinal chemistry MFM Borges, FMF Roleira, N Milhazes, EU Villare, LS Penin Frontiers in medicinal chemistry 4, 23-85, 2010 | 140 | 2010 |
Methamphetamine‐induced early increase of il‐6 and tnf‐α mrna expression in the mouse brain J Gonçalves, T Martins, R Ferreira, N Milhazes, F Borges, CF Ribeiro, ... Annals of the New York Academy of Sciences 1139 (1), 103-111, 2008 | 133 | 2008 |
Methamphetamine induces alterations on hippocampal NMDA and AMPA receptor subunit levels and impairs spatial working memory PF Simoes, AP Silva, FC Pereira, E Marques, S Grade, N Milhazes, ... Neuroscience 150 (2), 433-441, 2007 | 128 | 2007 |
Lipophilic phenolic antioxidants: Correlation between antioxidant profile, partition coefficients and redox properties FMF Roleira, C Siquet, E Orrù, EM Garrido, J Garrido, N Milhazes, ... Bioorganic & medicinal chemistry 18 (16), 5816-5825, 2010 | 119 | 2010 |
Structure− property− activity relationship of phenolic acids and derivatives. Protocatechuic acid alkyl esters B Reis, M Martins, B Barreto, N Milhazes, EM Garrido, P Silva, J Garrido, ... Journal of agricultural and food chemistry 58 (11), 6986-6993, 2010 | 119 | 2010 |
β-Nitrostyrene derivatives as potential antibacterial agents: A structure–property–activity relationship study N Milhazes, R Calheiros, MPM Marques, J Garrido, MNDS Cordeiro, ... Bioorganic & medicinal chemistry 14 (12), 4078-4088, 2006 | 115 | 2006 |
Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: an in vitro study using rat and human renal proximal tubular cells M Carvalho, G Hawksworth, N Milhazes, F Borges, TJ Monks, ... Archives of toxicology 76, 581-588, 2002 | 113 | 2002 |
Hepatotoxicity of 3, 4-methylenedioxyamphetamine and α-methyldopamine in isolated rat hepatocytes: formation of glutathione conjugates M Carvalho, N Milhazes, F Remião, F Borges, E Fernandes, F Amado, ... Archives of toxicology 78, 16-24, 2004 | 111 | 2004 |
Electrochemical oxidation of amphetamine-like drugs and application to electroanalysis of ecstasy in human serum E Garrido, J Garrido, N Milhazes, F Borges, AM Oliveira-Brett Bioelectrochemistry 79 (1), 77-83, 2010 | 110 | 2010 |
New insights into the antioxidant activity of hydroxycinnamic acids: Synthesis and physicochemical characterization of novel halogenated derivatives A Gaspar, EM Garrido, M Esteves, E Quezada, N Milhazes, J Garrido, ... European Journal of Medicinal Chemistry 44 (5), 2092-2099, 2009 | 110 | 2009 |
The toxicity of N-methyl-α-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine M Carvalho, F Remião, N Milhazes, F Borges, E Fernandes, F Carvalho, ... Toxicology 200 (2-3), 193-203, 2004 | 103 | 2004 |
Evaluation of the lipophilic properties of opioids, amphetamine-like drugs, and metabolites through electrochemical studies at the interface between two immiscible solutions R Gulaboski, MNDS Cordeiro, N Milhazes, J Garrido, F Borges, M Jorge, ... Analytical biochemistry 361 (2), 236-243, 2007 | 97 | 2007 |