| Selective covalent targeting of anti-apoptotic BFL-1 by cysteine-reactive stapled peptide inhibitors AJ Huhn, RM Guerra, EP Harvey, GH Bird, LD Walensky Cell chemical biology 23 (9), 1123-1134, 2016 | 72 | 2016 |
| Crystal structures of anti-apoptotic BFL-1 and its complex with a covalent stapled peptide inhibitor EP Harvey, HS Seo, RM Guerra, GH Bird, S Dhe-Paganon, LD Walensky Structure 26 (1), 153-160. e4, 2018 | 53 | 2018 |
| Homogeneous oligomers of pro-apoptotic BAX reveal structural determinants of mitochondrial membrane permeabilization ZJ Hauseman, EP Harvey, CE Newman, TE Wales, JC Bucci, J Mintseris, ... Molecular cell 79 (1), 68-83. e7, 2020 | 46 | 2020 |
| Identification of a covalent molecular inhibitor of anti-apoptotic BFL-1 by disulfide tethering EP Harvey, ZJ Hauseman, DT Cohen, TJ Rettenmaier, S Lee, AJ Huhn, ... Cell chemical biology 27 (6), 647-656. e6, 2020 | 34 | 2020 |
| An in silico method to assess antibody fragment polyreactivity EP Harvey, JE Shin, MA Skiba, GR Nemeth, JD Hurley, A Wellner, ... Nature Communications 13 (1), 7554, 2022 | 26 | 2022 |
| Precision targeting of BFL-1/A1 and an ATM co-dependency in human cancer RM Guerra, GH Bird, EP Harvey, NV Dharia, KJ Korshavn, MS Prew, ... Cell reports 24 (13), 3393-3403. e5, 2018 | 24 | 2018 |
| A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes BJ Pinch, DL Buckley, S Gleim, SM Brittain, L Tandeske, PL D'Alessandro, ... Cell chemical biology, 2021 | 10 | 2021 |
| Targeting a helix-in-groove interaction between E1 and E2 blocks ubiquitin transfer AM Cathcart, GH Bird, TE Wales, HD Herce, EP Harvey, ZJ Hauseman, ... Nature chemical biology 16 (11), 1218-1226, 2020 | 10 | 2020 |
| Identification of a structural determinant for selective targeting of HDMX Y Ben-Nun, HS Seo, EP Harvey, ZJ Hauseman, TE Wales, CE Newman, ... Structure 28 (7), 847-857. e5, 2020 | 3 | 2020 |
| Selective targeting of apoptosis proteins by structurally-stabilized and/or cysteine-reactive noxa peptides LD Walensky, GH Bird, R Guerra, E Harvey US Patent 11,834,520, 2023 | 2 | 2023 |
| A strategy to assess the cellular activity of E3 ligases against neo-substrates using electrophilic probes BJ Pinch, DL Buckley, S Gleim, SM Brittain, L Tandeske, PL D’Alessandro, ... BioRXiv, 2020.08. 13.249482, 2020 | 2 | 2020 |
| Selective targeting of apoptosis proteins by structurally-stabilized and/or cysteine-reactive noxa peptides LD Walensky, GH Bird, R Guerra, E Harvey US Patent App. 18/494,623, 2024 | | 2024 |
| Selective Targeting of Anti-Apoptotic BFL-1 by Cysteine Reactive Stapled Peptides and Disulfide-Tethering Fragments EP Harvey | | 2020 |
| Structural basis for selective therapeutic targeting of BFL-1 in cancer by a covalent stapled peptide inhibitor EP Harvey, HS Seo, RM Guerra, GH Bird, S Dhe-Paganon, LD Walensky Cancer Research 78 (13 Supplement), 1901-1901, 2018 | | 2018 |
| Reactivating apoptosis in BFL-1/A1 driven cancer with cysteine-reactive stapled peptide inhibitors RM Guerra, AJ Huhn, EP Harvey, GH Bird, LD Walensky Cancer Research 77 (13 Supplement), 2024-2024, 2017 | | 2017 |
Loren D. WalenskyProfessor of Pediatrics, Dana-Farber Cancer Institute and Harvard Medical School在 dfci.harvard.edu 的电子邮件经过验证
