Myc and cell cycle control G Bretones, MD Delgado, J León Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1849 (5), 506-516, 2015 | 805 | 2015 |
Myc roles in hematopoiesis and leukemia MD Delgado, J León Genes & cancer 1 (6), 605-616, 2010 | 303 | 2010 |
MYC oncogene contributions to release of cell cycle brakes L García-Gutiérrez, MD Delgado, J León Genes 10 (3), 244, 2019 | 197 | 2019 |
Functional phosphorylation sites in the C-terminal region of the multivalent multifunctional transcriptional factor CTCF EM Klenova, IV Chernukhin, A El-Kady, RE Lee, EM Pugacheva, ... Molecular and cellular biology 21 (6), 2221-2234, 2001 | 146 | 2001 |
p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells MJ Muñoz-Alonso, JC Acosta, C Richard, MD Delgado, J Sedivy, J León Journal of Biological Chemistry 280 (18), 18120-18129, 2005 | 126 | 2005 |
Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG … S Renaud, EM Pugacheva, MD Delgado, R Braunschweig, Z Abdullaev, ... Nucleic acids research 35 (21), 7372-7388, 2007 | 121 | 2007 |
Targeting of CTCF to the nucleolus inhibits nucleolar transcription through a poly (ADP-ribosyl) ation-dependent mechanism V Torrano, J Navascués, F Docquier, R Zhang, LJ Burke, I Chernukhin, ... Journal of cell science 119 (9), 1746-1759, 2006 | 118 | 2006 |
CTCF regulates the local epigenetic state of ribosomal DNA repeats S van de Nobelen, M Rosa-Garrido, J Leers, H Heath, W Soochit, ... Epigenetics & chromatin 3, 1-21, 2010 | 117 | 2010 |
CTCF regulates growth and erythroid differentiation of human myeloid leukemia cells V Torrano, I Chernukhin, F Docquier, V D'Arcy, J León, E Klenova, ... Journal of Biological Chemistry 280 (30), 28152-28161, 2005 | 99 | 2005 |
The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner F Sleutels, W Soochit, M Bartkuhn, H Heath, S Dienstbach, P Bergmaier, ... Epigenetics & chromatin 5, 1-21, 2012 | 98 | 2012 |
Differential regulation of Max and role of c-Myc during erythroid and myelomonocytic differentiation of K562 cells MD Delgado, A Lerga, M Cañelles, MT Gómez-Casares, J León Oncogene 10 (8), 1659-1666, 1995 | 95 | 1995 |
Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis? J Leon, N Ferrandiz, JC Acosta, MD Delgado Cell cycle 8 (8), 1148-1157, 2009 | 89 | 2009 |
Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest JC Acosta, N Ferrándiz, G Bretones, V Torrano, R Blanco, C Richard, ... Molecular and cellular biology 28 (24), 7286-7295, 2008 | 81 | 2008 |
c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells E Ceballos, MD Delgado, P Gutierrez, C Richard, D MuÈller, M Eilers, ... Oncogene 19 (18), 2194-2204, 2000 | 78 | 2000 |
Identification of a candidate tumor-suppressor gene specifically activated during Ras-induced senescence M Barradas, ES Gonos, Z Zebedee, E Kolettas, C Petropoulou, ... Experimental cell research 273 (2), 127-137, 2002 | 77 | 2002 |
MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib M Albajar, MT Gómez-Casares, J Llorca, I Mauleon, JP Vaqué, JC Acosta, ... Molecular Cancer Research 9 (5), 564-576, 2011 | 76 | 2011 |
Max and inhibitory c-Myc mutants induce erythroid differentiation and resistance to apoptosis in human myeloid leukemia cells M Cañelles, MD Delgado, KM Hyland, A Lerga, C Richard, CV Dang, ... Oncogene 14 (11), 1315-1327, 1997 | 75 | 1997 |
MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27KIP1 MT Gomez-Casares, E Garcia-Alegria, CE Lopez-Jorge, N Ferrándiz, ... Oncogene 32 (17), 2239-2246, 2013 | 71 | 2013 |
Levels of Gli3 repressor correlate with Bmp4 expression and apoptosis during limb development MF Bastida, MD Delgado, B Wang, JF Fallon, M Fernandez‐Teran, ... Developmental dynamics: an official publication of the American Association …, 2004 | 69 | 2004 |
H-, K-and N-Ras inhibit myeloid leukemia cell proliferation by a p21WAF1-dependent mechanism MD Delgado, JP Vaqué, I Arozarena, MA López-Ilasaca, C Martínez, ... Oncogene 19 (6), 783-790, 2000 | 69 | 2000 |