Computational approaches in target identification and drug discovery T Katsila, GA Spyroulias, GP Patrinos, MT Matsoukas Computational and structural biotechnology journal 14, 177-184, 2016 | 379 | 2016 |
Round and round we go: cyclic peptides in disease M Katsara, T Tselios, S Deraos, G Deraos, MT Matsoukas, E Lazoura, ... Current medicinal chemistry 13 (19), 2221-2232, 2006 | 194 | 2006 |
Review cyclic peptides on a merry‐go‐round; towards drug design A Tapeinou, MT Matsoukas, C Simal, T Tselios Peptide Science 104 (5), 453-461, 2015 | 125 | 2015 |
GPCRmd uncovers the dynamics of the 3D-GPCRome I Rodríguez-Espigares, M Torrens-Fontanals, JKS Tiemann, ... Nature Methods 17 (8), 777-787, 2020 | 114 | 2020 |
Cytochrome P450 CYP1 metabolism of hydroxylated flavones and flavonols: Selective bioactivation of luteolin in breast cancer cells NE Wilsher, RR Arroo, MT Matsoukas, AM Tsatsakis, DA Spandidos, ... Food and Chemical Toxicology 110, 383-394, 2017 | 61 | 2017 |
Citrullination of Linear and Cyclic Altered Peptide Ligands from Myelin Basic Protein (MBP87−99) Epitope Elicits a Th1 Polarized Response by T Cells Isolated … G Deraos, K Chatzantoni, MT Matsoukas, T Tselios, S Deraos, M Katsara, ... Journal of medicinal chemistry 51 (24), 7834-7842, 2008 | 59 | 2008 |
Design and Synthesis of a Cyclic Double Mutant Peptide (cyclo(87−99)[A91,A96]MBP87−99) Induces Altered Responses in Mice after Conjugation to Mannan … M Katsara, G Deraos, T Tselios, MT Matsoukas, I Friligou, J Matsoukas, ... Journal of medicinal chemistry 52 (1), 214-218, 2009 | 46 | 2009 |
Current understanding of the structure and function of family B GPCRs to design novel drugs V Karageorgos, M Venihaki, S Sakellaris, M Pardalos, G Kontakis, ... Hormones 17, 45-59, 2018 | 37 | 2018 |
Alamandine reverses hyperhomocysteinemia‐induced vascular dysfunction via PKA‐dependent mechanisms T Qaradakhi, MT Matsoukas, A Hayes, E Rybalka, M Caprnda, ... Cardiovascular therapeutics 35 (6), e12306, 2017 | 36 | 2017 |
Ligand binding determinants for angiotensin II type 1 receptor from computer simulations MT Matsoukas, A Cordomí, S Ríos, L Pardo, T Tselios Journal of chemical information and modeling 53 (11), 2874-2883, 2013 | 36 | 2013 |
Lysophosphatidic acid produced by autotaxin acts as an allosteric modulator of its catalytic efficiency F Salgado-Polo, A Fish, MT Matsoukas, T Heidebrecht, WJ Keune, ... Journal of Biological Chemistry 293 (37), 14312-14327, 2018 | 34 | 2018 |
Insights into AT1 Receptor Activation through AngII Binding Studies MT Matsoukas, C Potamitis, P Plotas, ME Androutsou, G Agelis, ... Journal of chemical information and modeling 53 (11), 2798-2811, 2013 | 34 | 2013 |
Nonconventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP OG Chepurny, MT Matsoukas, G Liapakis, CA Leech, BT Milliken, ... Journal of Biological Chemistry 294 (10), 3514-3531, 2019 | 28 | 2019 |
Identification of small-molecule inhibitors of calcineurin-NFATc signaling that mimic the PxIxIT motif of calcineurin binding partners MT Matsoukas, Á Aranguren-Ibáñez, T Lozano, V Nunes, JJ Lasarte, ... Science Signaling 8 (382), ra63-ra63, 2015 | 28 | 2015 |
Challenges in identifying large germline structural variants for clinical use by long read sequencing BJ Bizjan, T Katsila, T Tesovnik, R Šket, M Debeljak, MT Matsoukas, ... Computational and Structural Biotechnology Journal 18, 83-92, 2020 | 27 | 2020 |
Structural elucidation of Leuprolide and its analogues in solution: insight into their bioactive conformation DK Laimou, M Katsara, MTI Matsoukas, V Apostolopoulos, AN Troganis, ... Amino acids 39, 1147-1160, 2010 | 27 | 2010 |
The size matters? A computational tool to design bivalent ligands L Pérez-Benito, A Henry, MT Matsoukas, L Lopez, D Pulido, M Royo, ... Bioinformatics 34 (22), 3857-3863, 2018 | 26 | 2018 |
Novel Hit Compounds as Putative Antifungals: The Case of Aspergillus fumigatus E Kritsi, MT Matsoukas, C Potamitis, A Detsi, M Ivanov, M Sokovic, ... Molecules 24 (21), 3853, 2019 | 24 | 2019 |
Cell-active carbazole derivatives as inhibitors of the zika virus protease G Rassias, V Zogali, CMD Swarbrick, KWK Chan, SA Chan, CP Gwee, ... European Journal of Medicinal Chemistry 180, 536-545, 2019 | 23 | 2019 |
Functional elements of the gastric inhibitory polypeptide receptor: Comparison between secretin-and rhodopsin-like G protein-coupled receptors A Cordomi, S Ismail, MT Matsoukas, C Escrieut, MJ Gherardi, L Pardo, ... Biochemical pharmacology 96 (3), 237-246, 2015 | 22 | 2015 |