Parkin and PINK1 mitigate STING-induced inflammation DA Sliter, J Martinez, L Hao, XI Chen, N Sun, TD Fischer, JL Burman, Y Li, ... Nature 561 (7722), 258-262, 2018 | 1060 | 2018 |
Leucine‐rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER–Golgi export HJ Cho, J Yu, C Xie, P Rudrabhatla, X Chen, J Wu, L Parisiadou, G Liu, ... The EMBO journal 33 (20), 2314-2331, 2014 | 88 | 2014 |
Longitudinal metabolomics profiling of Parkinson’s disease-related α-synuclein A53T transgenic mice X Chen, C Xie, L Sun, J Ding, H Cai PloS one 10 (8), e0136612, 2015 | 61 | 2015 |
Aldehyde dehydrogenase 1–positive nigrostriatal dopaminergic fibers exhibit distinct projection pattern and dopamine release dynamics at mouse dorsal striatum C Sgobio, J Wu, W Zheng, X Chen, J Pan, AG Salinas, MI Davis, ... Scientific reports 7 (1), 5283, 2017 | 42 | 2017 |
Parkinson’s disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging X Chen, C Xie, W Tian, L Sun, W Zheng, S Hawes, L Chang, J Kung, ... Molecular neurodegeneration 15, 1-19, 2020 | 40 | 2020 |
Leucine-Rich Repeat Kinase 2 (Lrrk2) Deficiency Diminishes the Development of Experimental Autoimmune Uveitis (EAU) and the Adaptive Immune Response WS Wandu, C Tan, O Ogbeifun, BP Vistica, G Shi, SJH Hinshaw, C Xie, ... PloS one 10 (6), e0128906, 2015 | 32 | 2015 |
Activation of dopamine receptor D1 inhibits glioblastoma tumorigenicity by regulating autophagic activity K Yang, M Wei, Z Yang, Z Fu, R Xu, C Cheng, X Chen, S Chen, ... Cellular Oncology 43, 1175-1190, 2020 | 27 | 2020 |
Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration P Wang, X Chen, Y Wang, C Jia, X Liu, Y Wang, H Wu, H Cai, HM Shen, ... Cell death & disease 12 (1), 116, 2021 | 25 | 2021 |
Roles of transcription factors in the development and reprogramming of the dopaminergic neurons L Tian, M Al-Nusaif, X Chen, S Li, W Le International Journal of Molecular Sciences 23 (2), 845, 2022 | 19 | 2022 |
Massive Human Co‐Expression Network and Its Medical Applications Y Feng, J Hurst, M Almeida‐De‐Macedo, X Chen, L Li, N Ransom, ... Chemistry & biodiversity 9 (5), 868-887, 2012 | 19 | 2012 |
New understanding on the pathophysiology and treatment of constipation in Parkinson’s disease J Xu, L Wang, X Chen, W Le Frontiers in Aging Neuroscience 14, 917499, 2022 | 18 | 2022 |
Research advances on L-DOPA-induced dyskinesia: from animal models to human disease X Chen, Y Wang, H Wu, C Cheng, W Le Neurological Sciences 41, 2055-2065, 2020 | 17 | 2020 |
No apparent transmission of transgenic α–synuclein into nigrostriatal dopaminergic neurons in multiple mouse models N Sastry, W Zheng, G Liu, H Wang, X Chen, M Cai, P Contractor, ... Translational neurodegeneration 4, 1-9, 2015 | 12 | 2015 |
Whole-genome thermodynamic analysis reduces siRNA off-target effects X Chen, P Liu, HH Chou PLoS One 8 (3), e58326, 2013 | 11 | 2013 |
The essential role of transcription factor Pitx3 in preventing mesodiencephalic dopaminergic neurodegeneration and maintaining neuronal subtype identities during aging Y Wang, X Chen, Y Wang, S Li, H Cai, W Le Cell death & disease 12 (11), 1008, 2021 | 10 | 2021 |
α-Synuclein Up-regulates Monoamine Oxidase A Expression and Activity via Trans-Acting Transcription Factor 1 C Jia, C Cheng, T Li, X Chen, Y Yang, X Liu, S Li, W Le Frontiers in Aging Neuroscience 13, 653379, 2021 | 10 | 2021 |
The role of Nurr1-miR-30e-5p-NLRP3 axis in inflammation-mediated neurodegeneration: insights from mouse models and patients’ studies in Parkinson’s disease T Li, X Tan, L Tian, C Jia, C Cheng, X Chen, M Wei, Y Wang, Y Hu, Q Jia, ... Journal of Neuroinflammation 20 (1), 274, 2023 | 5 | 2023 |
Oxygen metabolism abnormality and Alzheimer's disease: An update G Liu, C Yang, X Wang, X Chen, Y Wang, W Le Redox Biology, 102955, 2023 | 5 | 2023 |
Pitx3 deficiency promotes age-dependent alterations in striatal medium spiny neurons X Chen, Z Yang, Y Shao, K Kim, Y Wang, Y Wang, H Wu, X Xu, W Le Frontiers in Aging Neuroscience 14, 960479, 2022 | 5 | 2022 |
MicroRNA-target binding structures mimic microRNA duplex structures in humans X Chen, L Shen, HH Chou PLoS One 9 (2), e88806, 2014 | 5 | 2014 |