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Ana Cristina Puhl
Ana Cristina Puhl
Senior Scientist , Collaborations Pharmaceuticals
在 collaborationspharma.com 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Design of amidobenzimidazole STING receptor agonists with systemic activity
JM Ramanjulu, GS Pesiridis, J Yang, N Concha, R Singhaus, SY Zhang, ...
Nature 564 (7736), 439-443, 2018
5902018
Exploiting machine learning for end-to-end drug discovery and development
S Ekins, AC Puhl, KM Zorn, TR Lane, DP Russo, JJ Klein, AJ Hickey, ...
Nature materials 18 (5), 435-441, 2019
4532019
Déjà vu: stimulating open drug discovery for SARS-CoV-2
S Ekins, M Mottin, PRPS Ramos, BKP Sousa, BJ Neves, DH Foil, KM Zorn, ...
Drug discovery today 25 (5), 928-941, 2020
1102020
Mode of peroxisome proliferator-activated receptor γ activation by luteolin
AC Puhl, A Bernardes, RL Silveira, J Yuan, JLO Campos, ...
Molecular pharmacology 81 (6), 788-799, 2012
1092012
Mechanisms of peroxisome proliferator activated receptor γ regulation by non-steroidal anti-inflammatory drugs
AC Puhl, FA Milton, A Cvoro, DH Sieglaff, JCL Campos, A Bernardes, ...
Nuclear receptor signaling 13 (1), nrs. 13004, 2015
922015
Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms
AC Puhl, EJ Fritch, TR Lane, LV Tse, BL Yount, CQ Sacramento, ...
ACS omega 6 (11), 7454-7468, 2021
722021
Identification of a new hormone-binding site on the surface of thyroid hormone receptor
PCT Souza, AC Puhl, L Martínez, R Aparício, AS Nascimento, ...
Molecular endocrinology 28 (4), 534-545, 2014
452014
Machine learning models identify inhibitors of SARS-CoV-2
VO Gawriljuk, PPK Zin, AC Puhl, KM Zorn, DH Foil, TR Lane, B Hurst, ...
Journal of chemical information and modeling 61 (9), 4224-4235, 2021
442021
Recent advances in drug repurposing using machine learning
F Urbina, AC Puhl, S Ekins
Current opinion in chemical biology 65, 74-84, 2021
412021
Inhibition of inositol polyphosphate kinases by quercetin and related flavonoids: A structure–activity analysis
C Gu, MA Stashko, AC Puhl-Rubio, M Chakraborty, A Chakraborty, ...
Journal of medicinal chemistry 62 (3), 1443-1454, 2019
412019
Preparation and characterization of polymeric nanoparticles loaded with the flavonoid luteolin, by using factorial design.
AC Puhl, M Fagundes, KC Dos Santos, I Polikarpov, MFD Graças, ...
International journal of drug delivery 3 (4), 683, 2011
402011
Stealth and non-stealth nanocapsules containing camptothecin: in-vitro and in-vivo activity on B16-F10 melanoma
G Loch-Neckel, D Nemen, AC Puhl, D Fernandes, MA Stimamiglio, ...
Journal of Pharmacy and Pharmacology 59 (10), 1359-1364, 2007
322007
Covalent immobilization of tobacco‐etch‐virus NIa protease: a useful tool for cleavage of the histidine tag of recombinant proteins
AC Puhl, C Giacomini, G Irazoqui, F Batista‐Viera, A Villarino, H Terenzi
Biotechnology and applied biochemistry 53 (3), 165-174, 2009
262009
Machine learning for discovery of GSK3β inhibitors
PA Vignaux, E Minerali, DH Foil, AC Puhl, S Ekins
ACS omega 5 (41), 26551-26561, 2020
242020
New targets for HIV drug discovery
AC Puhl, AG Demo, VA Makarov, S Ekins
Drug discovery today 24 (5), 1139-1147, 2019
242019
Discovery and development of cyclic peptide inhibitors of CIB1
VA Haberman, SR Fleming, TM Leisner, AC Puhl, E Feng, L Xie, X Chen, ...
ACS Medicinal Chemistry Letters 12 (11), 1832-1839, 2021
212021
Development of machine learning models and the discovery of a new antiviral compound against yellow fever virus
VO Gawriljuk, DH Foil, AC Puhl, KM Zorn, TR Lane, O Riabova, ...
Journal of chemical information and modeling 61 (8), 3804-3813, 2021
212021
Use of protein kinase–focused compound libraries for the discovery of new inositol phosphate kinase inhibitors
AC Puhl-Rubio, MA Stashko, H Wang, PB Hardy, V Tyagi, B Li, X Wang, ...
SLAS DISCOVERY: Advancing Life Sciences R&D 23 (9), 982-988, 2018
212018
Pyronaridine protects against SARS-CoV-2 infection in mouse
AC Puhl, GF Gomes, S Damasceno, AS Godoy, GD Noske, AM Nakamura, ...
ACS Infectious Diseases 8 (6), 1147-1160, 2022
162022
The antiviral drug tilorone is a potent and selective inhibitor of acetylcholinesterase
PA Vignaux, E Minerali, TR Lane, DH Foil, PB Madrid, AC Puhl, S Ekins
Chemical research in toxicology 34 (5), 1296-1307, 2021
162021
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