Recent insights on glutamatergic dysfunction in Alzheimer’s disease and therapeutic implications PD Pinky, JC Pfitzer, J Senfeld, H Hong, S Bhattacharya, ... The Neuroscientist 29 (4), 461-471, 2023 | 17 | 2023 |
rTg(TauP301L)4510 mice exhibit increased VGlut1 in hippocampal presynaptic glutamatergic vesicles and increased extracellular glutamate release E Taipala, JC Pfitzer, M Hellums, MN Reed, MW Gramlich Frontiers in Synaptic Neuroscience 14, 925546, 2022 | 4 | 2022 |
Differential Effects of Human P301L Tau Expression in Young versus Aged Mice HC Hunsberger, SE Setti, CC Rudy, DS Weitzner, JC Pfitzer, ... International journal of molecular sciences 22 (21), 11637, 2021 | 3 | 2021 |
Troriluzole rescues glutamatergic deficits, amyloid and tau pathology, and synaptic and memory impairments in 3xTg‐AD mice J Pfitzer, PD Pinky, S Perman, E Redmon, L Cmelak, V Suppiramaniam, ... Journal of Neurochemistry, 2024 | 2 | 2024 |
Prenatal Cannabinoid Exposure Elicits Memory Deficits Associated with Reduced PSA-NCAM Expression, Altered Glutamatergic Signaling, and Adaptations in Hippocampal Synaptic … PD Pinky, J Bloemer, WD Smith, Y Du, RT Heslin, SE Setti, JC Pfitzer, ... Cells 12 (21), 2525, 2023 | 2 | 2023 |
Single-Cell Multi-Ome Analysis Reveals Novel Molecular Mechanisms Underlying Subclonal Response to Survivin Inhibition in Relapsed/Refractory Multiple Myeloma A Chakrabortty, H Kumar, J Pfitzer, N Sharma, R Waliagha, U Mukherjee, ... Blood 142, 6616, 2023 | 1 | 2023 |
Preclinical Development of a Novel Pan-RAS Inhibitor Against Relapsed/Refractory Multiple Myeloma JC Pfitzer, R Waliagha, LB Baughn, AB Keeton, X Chen, Y Maxuitenko, ... Blood 144, 3263, 2024 | | 2024 |
Riluzole prodrug alters hippocampal glutamatergic function: a mechanism for the amelioration of synaptic plasticity and memory deficits observed in a preclinical Alzheimer’s … J Pfitzer | | 2023 |
Mutant N-and K-Ras Show Distinct Effects on Growth, Signaling and Drug Response in CRISPR-Cas Edited Alleles of a Myeloma Cell Line B Van Ness, AK Mitra, L Wiesen, LB Baughn, SK Kumar, J Petit, J Pfizer, ... Blood 142, 3320, 2023 | | 2023 |
Mitochondria Exhibit Changes in Morphology/Function to Support Increased Glutamate Release in TauP301L Neurons Prior to Reduction in Presynaptic Vesicle … R Cotter, M Hellums, D Gray, D Batista, J Pfitzer, MN Reed, MW Gramlich bioRxiv, 2023.06. 30.547132, 2023 | | 2023 |
P301L Tau Mediates Increased Glutamate Release in Hippocampal Neurons Via Increased VGLUT1 in Tauopathy Mouse Model M Gramlich, E Taipala, J Pfitzer, M Hellums, M Reed APS March Meeting Abstracts 2023, M52. 009, 2023 | | 2023 |