SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout V Vitart, I Rudan, C Hayward, NK Gray, J Floyd, CNA Palmer, SA Knott, ... Nature genetics 40 (4), 437-442, 2008 | 962 | 2008 |
The many facets of the Wilms' tumour gene, WT1 P Hohenstein, ND Hastie Human molecular genetics 15 (suppl_2), R196-R201, 2006 | 459 | 2006 |
Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin OM Martínez-Estrada, LA Lettice, A Essafi, JA Guadix, J Slight, V Velecela, ... Nature genetics 42 (1), 89-93, 2010 | 428 | 2010 |
Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation JA Davies, M Ladomery, P Hohenstein, L Michael, A Shafe, L Spraggon, ... Human molecular genetics 13 (2), 235-246, 2004 | 270 | 2004 |
Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations R Rojo, A Raper, DD Ozdemir, L Lefevre, K Grabert, ... Nature communications 10 (1), 3215, 2019 | 264 | 2019 |
Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy TM Wishart, CA Mutsaers, M Riessland, MM Reimer, G Hunter, ... The Journal of clinical investigation 124 (4), 1821-1834, 2014 | 207 | 2014 |
A wt1-controlled chromatin switching mechanism underpins tissue-specific wnt4 activation and repression A Essafi, A Webb, RL Berry, J Slight, SF Burn, L Spraggon, V Velecela, ... Developmental cell 21 (3), 559-574, 2011 | 186 | 2011 |
The yin and yang of kidney development and Wilms’ tumors P Hohenstein, K Pritchard-Jones, J Charlton Genes & development 29 (5), 467-482, 2015 | 166 | 2015 |
Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1 YY Chau, D Brownstein, H Mjoseng, WC Lee, N Buza-Vidas, C Nerlov, ... PLoS genetics 7 (12), e1002404, 2011 | 161 | 2011 |
Wt1 and retinoic acid signaling are essential for stellate cell development and liver morphogenesis A Ijpenberg, JM Perez-Pomares, JA Guadix, R Carmona, ... Developmental biology 312 (1), 157-170, 2007 | 154 | 2007 |
Fucci2a: A bicistronic cell cycle reporter that allows Cre mediated tissue specific expression in mice RL Mort, MJ Ford, A Sakaue-Sawano, NO Lindstrom, A Casadio, ... Cell cycle 13 (17), 2681-2696, 2014 | 147 | 2014 |
WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland R Bandiera, VPI Vidal, FJ Motamedi, M Clarkson, I Sahut-Barnola, ... Developmental cell 27 (1), 5-18, 2013 | 142 | 2013 |
Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease O Harari‐Steinberg, S Metsuyanim, D Omer, Y Gnatek, R Gershon, ... EMBO molecular medicine 5 (10), 1556-1568, 2013 | 124 | 2013 |
Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron NO Lindström, ML Lawrence, SF Burn, JA Johansson, ERM Bakker, ... Elife 4, e04000, 2015 | 107 | 2015 |
WT1 in disease: shifting the epithelial–mesenchymal balance E Miller‐Hodges, P Hohenstein The Journal of pathology 226 (2), 229-240, 2012 | 106 | 2012 |
Calcium/NFAT signalling promotes early nephrogenesis SF Burn, A Webb, RL Berry, JA Davies, A Ferrer-Vaquer, ... Developmental biology 352 (2), 288-298, 2011 | 100 | 2011 |
The Wilms’ tumour suppressor Wt1 is a major regulator of tumour angiogenesis and progression KD Wagner, J Cherfils-Vicini, N Hosen, P Hohenstein, E Gilson, ... Nature communications 5 (1), 5852, 2014 | 96 | 2014 |
2- and 3-dimensional synthetic large-scale de novo patterning by mammalian cells through phase separation E Cachat, W Liu, KC Martin, X Yuan, H Yin, P Hohenstein, JA Davies Scientific reports 6 (1), 20664, 2016 | 89 | 2016 |
Smad4 haploinsufficiency in mouse models for intestinal cancer P Alberici, S Jagmohan-Changur, E De Pater, M Van Der Valk, R Smits, ... Oncogene 25 (13), 1841-1851, 2006 | 89 | 2006 |
Osteocalcin regulates arterial calcification via altered Wnt signaling and glucose metabolism NA Rashdan, AM Sim, L Cui, K Phadwal, FL Roberts, R Carter, ... Journal of Bone and Mineral Research 35 (2), 357-367, 2020 | 88 | 2020 |