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Youngrae Kim
Youngrae Kim
Research associate, University of Iowa
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Histone and DNA methylation–mediated epigenetic downregulation of endothelial Kruppel-like factor 2 by low-density lipoprotein cholesterol
A Kumar, S Kumar, A Vikram, TA Hoffman, A Naqvi, CM Lewarchik, ...
Arteriosclerosis, thrombosis, and vascular biology 33 (8), 1936-1942, 2013
1402013
Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc
CS Kim, YR Kim, A Naqvi, S Kumar, TA Hoffman, SB Jung, A Kumar, ...
Cardiovascular research 92 (3), 466-475, 2011
1332011
Vascular microRNA-204 is remotely governed by the microbiome and impairs endothelium-dependent vasorelaxation by downregulating Sirtuin1
A Vikram, YR Kim, S Kumar, Q Li, M Kassan, JS Jacobs, K Irani
Nature communications 7 (1), 12565, 2016
1162016
Novel anti-apoptotic mechanism of A20 through targeting ASK1 to suppress TNF-induced JNK activation
M Won, KA Park, HS Byun, KC Sohn, YR Kim, J Jeon, JH Hong, J Park, ...
Cell Death & Differentiation 17 (12), 1830-1841, 2010
1042010
Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction
S Kumar, YR Kim, A Vikram, A Naqvi, Q Li, M Kassan, V Kumar, ...
Proceedings of the National Academy of Sciences 114 (7), 1714-1719, 2017
1012017
P66Shc-induced microRNA-34a causes diabetic endothelial dysfunction by downregulating Sirtuin1
Q Li, YR Kim, A Vikram, S Kumar, M Kassan, M Gabani, SK Lee, ...
Arteriosclerosis, thrombosis, and vascular biology 36 (12), 2394-2403, 2016
782016
Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel
A Vikram, CM Lewarchik, JY Yoon, A Naqvi, S Kumar, GM Morgan, ...
Nature medicine 23 (3), 361-367, 2017
772017
Caspase-8 has an essential role in resveratrol-induced apoptosis of rheumatoid fibroblast-like synoviocytes
HS Byun, JK Song, YR Kim, L Piao, M Won, KA Park, BL Choi, H Lee, ...
Rheumatology 47 (3), 301-308, 2008
772008
Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: the protective role of autophagy in apoptosis
KS Song, JS Kim, EJ Yun, YR Kim, KS Seo, JH Park, YJ Jung, JI Park, ...
Autophagy 4 (5), 650-658, 2008
732008
Epigenetic upregulation of p66shc mediates low-density lipoprotein cholesterol-induced endothelial cell dysfunction
YR Kim, CS Kim, A Naqvi, A Kumar, S Kumar, TA Hoffman, K Irani
American Journal of Physiology-Heart and Circulatory Physiology 303 (2 …, 2012
712012
Canonical Wnt Signaling Induces Vascular Endothelial Dysfunction via p66Shc-Regulated Reactive Oxygen Species
A Vikram, YR Kim, S Kumar, A Naqvi, TA Hoffman, A Kumar, FJ Miller Jr, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 34 (10), 2301-2309, 2014
702014
Protein kinase SGK1 enhances MEK/ERK complex formation through the phosphorylation of ERK2: implication for the positive regulatory role of SGK1 on the ERK function during …
M Won, KA Park, HS Byun, YR Kim, BL Choi, JH Hong, J Park, JH Seok, ...
Journal of hepatology 51 (1), 67-76, 2009
542009
MicroRNA-204 promotes vascular endoplasmic reticulum stress and endothelial dysfunction by targeting Sirtuin1
M Kassan, A Vikram, Q Li, YR Kim, S Kumar, M Gabani, J Liu, JS Jacobs, ...
Scientific reports 7 (1), 9308, 2017
512017
Cyanidin-3‑glucoside isolated from mulberry fruits protects pancreatic β-cells against glucotoxicity-induced apoptosis
JS Lee, YR Kim, JM Park, YE Kim, NI Baek, EK Hong
Molecular medicine reports 11 (4), 2723-2728, 2015
482015
A single-nucleotide variation in a p53-binding site affects nutrient-sensitive human SIRT1 expression
A Naqvi, TA Hoffman, J DeRicco, A Kumar, CS Kim, SB Jung, T Yamamori, ...
Human Molecular Genetics 19 (21), 4123-4133, 2010
452010
Redox factor-1 activates endothelial SIRTUIN1 through reduction of conserved cysteine sulfhydryls in its deacetylase domain
SB Jung, CS Kim, YR Kim, A Naqvi, T Yamamori, S Kumar, A Kumar, ...
PLoS One 8 (6), e65415, 2013
422013
Modulatory role of phospholipase D in the activation of signal transducer and activator of transcription (STAT)-3 by thyroid oncogenic kinase RET/PTC
YR Kim, HS Byun, M Won, KA Park, JM Kim, BL Choi, H Lee, JH Hong, ...
BMC cancer 8, 1-11, 2008
392008
Mulberry fruit extract protects pancreatic β-cells against hydrogen peroxide-induced apoptosis via antioxidative activity
JS Lee, YR Kim, JM Park, SJ Ha, YE Kim, NI Baek, EK Hong
Molecules 19 (7), 8904-8915, 2014
362014
Enhancement of lysophosphatidic acid-induced ERK phosphorylation by phospholipase D1 via the formation of phosphatidic acid
JH Hong, SO Oh, M Lee, YR Kim, DU Kim, GM Hur, JH Lee, K Lim, ...
Biochemical and biophysical research communications 281 (5), 1337-1342, 2001
362001
Regulation of Phospholipase D2 by H2O2 in PC12 Cells
SO Oh, JH Hong, YR Kim, HS Yoo, SH Lee, K Lim, BD Hwang, JH Exton, ...
Journal of neurochemistry 75 (6), 2445-2454, 2000
352000
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