Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1 O Sukocheva, C Wadham, A Holmes, N Albanese, E Verrier, F Feng, ... The Journal of cell biology 173 (2), 301-310, 2006 | 261 | 2006 |
High-density lipoproteins neutralize C-reactive protein proinflammatory activity C Wadham, N Albanese, J Roberts, L Wang, CJ Bagley, JR Gamble, ... Circulation 109 (17), 2116-2122, 2004 | 242 | 2004 |
Integrative genomic analysis reveals cancer-associated mutations at diagnosis of CML in patients with high-risk disease S Branford, P Wang, DT Yeung, D Thomson, A Purins, C Wadham, ... Blood, The Journal of the American Society of Hematology 132 (9), 948-961, 2018 | 183 | 2018 |
PPARγ agonists ameliorate endothelial cell activation via inhibition of diacylglycerol–protein kinase C signaling pathway: role of diacylglycerol kinase E Verrier, L Wang, C Wadham, N Albanese, C Hahn, JR Gamble, ... Circulation research 94 (11), 1515-1522, 2004 | 145 | 2004 |
FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: a protective role of autophagy N Zhang, Y Qi, C Wadham, L Wang, A Warren, W Di, P Xia Autophagy 6 (8), 1157-1167, 2010 | 142 | 2010 |
The protein tyrosine phosphatase Pez is a major phosphatase of adherens junctions and dephosphorylates β-catenin C Wadham, JR Gamble, MA Vadas, Y Khew-Goodall Molecular biology of the cell 14 (6), 2520-2529, 2003 | 120 | 2003 |
The protein tyrosine phosphatase Pez regulates TGFβ, epithelial–mesenchymal transition, and organ development L Wyatt, C Wadham, LA Crocker, M Lardelli, Y Khew-Goodall The Journal of cell biology 178 (7), 1223-1235, 2007 | 101 | 2007 |
Activation of the Sphingosine Kinase–Signaling Pathway by High Glucose Mediates the Proinflammatory Phenotype of Endothelial Cells L Wang, XP Xing, A Holmes, C Wadham, JR Gamble, MA Vadas, P Xia Circulation research 97 (9), 891-899, 2005 | 90 | 2005 |
High glucose attenuates protein S-nitrosylation in endothelial cells: role of oxidative stress C Wadham, A Parker, L Wang, P Xia Diabetes 56 (11), 2715-2721, 2007 | 87 | 2007 |
The role of sphingolipid signalling in diabetes‑associated pathologies ML Ng, C Wadham, OA Sukocheva International journal of molecular medicine 39 (2), 243-252, 2017 | 85 | 2017 |
Stat6 activation is essential for interleukin-4 induction of P-selectin transcription in human umbilical vein endothelial cells Y Khew-Goodall, C Wadham, BN Stein, JR Gamble, MA Vadas Arteriosclerosis, thrombosis, and vascular biology 19 (6), 1421-1429, 1999 | 82 | 1999 |
Molecular profiling of childhood cancer: Biomarkers and novel therapies F Saletta, C Wadham, DS Ziegler, GM Marshall, M Haber, G McCowage, ... BBA clinical 1, 59-77, 2014 | 70 | 2014 |
Dimethylarginine dimethylaminohydrolase regulation: a novel therapeutic target in cardiovascular disease C Wadham, AA Mangoni Expert opinion on drug metabolism & toxicology 5 (3), 303-319, 2009 | 64 | 2009 |
Translocation of protein tyrosine phosphatase Pez/PTPD2/PTP36 to the nucleus is associated with induction of cell proliferation C Wadham, JR Gamble, MA Vadas, Y Khew-Goodall Journal of cell science 113 (17), 3117-3123, 2000 | 62 | 2000 |
Sphingosine 1-phosphate, a key mediator of the cytokine network: juxtacrine signaling P Xia, C Wadham Cytokine & growth factor reviews 22 (1), 45-53, 2011 | 57 | 2011 |
Role of sphingolipids in oestrogen signalling in breast cancer cells: an update O Sukocheva, C Wadham Journal of Endocrinology 220 (3), R25-R35, 2014 | 41 | 2014 |
Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2 G Aji, Y Huang, ML Ng, W Wang, T Lan, M Li, Y Li, Q Chen, R Li, S Yan, ... Proceedings of the National Academy of Sciences 117 (39), 24434-24442, 2020 | 40 | 2020 |
Estrogen defines the dynamics and destination of transactivated EGF receptor in breast cancer cells: Role of S1P3 receptor and Cdc42 O Sukocheva, C Wadham, P Xia Experimental cell research 319 (4), 455-465, 2013 | 40 | 2013 |
Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin H Zhang, Y Chen, C Wadham, GW McCaughan, FM Keane, MD Gorrell Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1853 (2), 470-480, 2015 | 38 | 2015 |
Aberrant RAG-mediated recombination contributes to multiple structural rearrangements in lymphoid blast crisis of chronic myeloid leukemia DW Thomson, NH Shahrin, PPS Wang, C Wadham, N Shanmuganathan, ... Leukemia 34 (8), 2051-2063, 2020 | 36 | 2020 |