17‐beta hydroxysteroid dehydrogenase 13 is a hepatic retinol dehydrogenase associated with histological features of nonalcoholic fatty liver disease Y Ma, OV Belyaeva, PM Brown, K Fujita, K Valles, S Karki, YS de Boer, ... Hepatology 69 (4), 1504-1519, 2019 | 230 | 2019 |
Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease LH Maguire, SK Handelman, X Du, Y Chen, TH Pers, EK Speliotes Nature genetics 50 (10), 1359-1365, 2018 | 120 | 2018 |
Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology VL Chen, X Du, Y Chen, A Kuppa, SK Handelman, RB Vohnoutka, ... Nature communications 12 (1), 816, 2021 | 91 | 2021 |
Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease Y Chen, X Du, A Kuppa, MF Feitosa, LF Bielak, JR O’Connell, SK Musani, ... Nature genetics 55 (10), 1640-1650, 2023 | 54 | 2023 |
Genetic variants that associate with cirrhosis have pleiotropic effects on human traits VL Chen, Y Chen, X Du, SK Handelman, EK Speliotes Liver International 40 (2), 405-415, 2020 | 45 | 2020 |
PNPLA3 genotype and diabetes identify patients with nonalcoholic fatty liver disease at high risk of incident cirrhosis VL Chen, A Oliveri, MJ Miller, K Wijarnpreecha, X Du, Y Chen, ... Gastroenterology 164 (6), 966-977. e17, 2023 | 41 | 2023 |
HSD17B13 is a hepatic retinol dehydrogenase associated with histological features of non-alcoholic fatty liver disease Y Ma, OV Belyaeva, PM Brown, K Fujita, K Valles, S Karki, YS de Boer, ... Hepatology (Baltimore, Md.) 69 (4), 1504, 2019 | 29 | 2019 |
Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer’s disease and myocardial infarction ND Palmer, B Kahali, A Kuppa, Y Chen, X Du, MF Feitosa, LF Bielak, ... Human molecular genetics 30 (15), 1443-1456, 2021 | 26 | 2021 |
Body composition and genetic lipodystrophy risk score associate with nonalcoholic fatty liver disease and liver fibrosis VL Chen, AP Wright, B Halligan, Y Chen, X Du, SK Handelman, MT Long, ... Hepatology Communications 3 (8), 1073-1084, 2019 | 24 | 2019 |
Comprehensive genetic study of the insulin resistance marker TG: HDL-C in the UK Biobank A Oliveri, RJ Rebernick, A Kuppa, A Pant, Y Chen, X Du, KC Cushing, ... Nature genetics 56 (2), 212-221, 2024 | 20 | 2024 |
Hepatic decompensation is accelerated in patients with cirrhosis and alpha-1 antitrypsin Pi∗ MZ genotype VL Chen, DA Burkholder, IJ Moran, JV DiBattista, MJ Miller, Y Chen, X Du, ... JHEP Reports 4 (6), 100483, 2022 | 17 | 2022 |
A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction B Kahali, Y Chen, MF Feitosa, LF Bielak, JR O’Connell, SK Musani, ... The Journal of Clinical Endocrinology & Metabolism 106 (2), 372-387, 2021 | 14 | 2021 |
Inflammatory bowel disease risk variants are associated with an increased risk of skin cancer KC Cushing, X Du, Y Chen, LC Stetson, A Kuppa, VL Chen, ... Inflammatory Bowel Diseases 28 (11), 1667-1676, 2022 | 9 | 2022 |
Polygenic risk prediction in diverticulitis AC De Roo, Y Chen, X Du, S Handelman, M Byrnes, SE Regenbogen, ... Annals of surgery 277 (6), e1262-e1268, 2023 | 8 | 2023 |
Population‐based meta‐analysis and gene‐set enrichment identifies FXR/RXR pathway as common to fatty liver disease and serum lipids SK Handelman, YM Puentes, A Kuppa, Y Chen, X Du, MF Feitosa, ... Hepatology Communications 6 (11), 3120-3131, 2022 | 8 | 2022 |
Perturbation of TM6SF2 Expression Alters Lipid Metabolism in a Human Liver Cell Line A Pant, Y Chen, A Kuppa, X Du, BD Halligan, EK Speliotes International Journal of Molecular Sciences 22 (18), 9758, 2021 | 7 | 2021 |
Genetic risk accentuates dietary effects on hepatic steatosis, inflammation and fibrosis in a population-based cohort VL Chen, X Du, A Oliveri, Y Chen, A Kuppa, BD Halligan, MA Province, ... Journal of Hepatology, 2024 | 4 | 2024 |
Risk Variants in or Near ZBTB40 AND NFATC1 Increase the Risk of Both IBD and Adverse Bone Health Outcomes Highlighting Common Genetic Underpinnings … KC Cushing, Y Chen, X Du, V Chen, A Kuppa, P Higgins, EK Speliotes Inflammatory Bowel Diseases 29 (6), 938-945, 2023 | 3 | 2023 |
Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity RB Vohnoutka, A Kuppa, Y Hegde, Y Chen, A Pant, ME Tohme, EYK Choi, ... Journal of molecular endocrinology 70 (3), 2023 | 2 | 2023 |
Genetic variants that associate with liver cirrhosis have pleiotropic effects on human traits VL Chen, Y Chen, X Du, S Handelman, EK Speliotes HEPATOLOGY 70, 1142A-1142A, 2019 | 2 | 2019 |