| The dual PI3Kδ/CK1ε inhibitor umbralisib exhibits unique immunomodulatory effects on CLL T cells K Maharaj, JJ Powers, A Achille, M Mediavilla-Varela, W Gamal, ... Blood advances 4 (13), 3072-3084, 2020 | 65 | 2020 |
| Essential role for histone deacetylase 11 (HDAC11) in neutrophil biology E Sahakian, J Chen, JJ Powers, X Chen, K Maharaj, SL Deng, AN Achille, ... Journal of leukocyte biology 102 (2), 475-486, 2017 | 56 | 2017 |
| Emerging role of BCR signaling inhibitors in immunomodulation of chronic lymphocytic leukemia K Maharaj, E Sahakian, J Pinilla-Ibarz Blood advances 1 (21), 1867-1875, 2017 | 28 | 2017 |
| Silencing of HDAC6 as a therapeutic target in chronic lymphocytic leukemia K Maharaj, JJ Powers, A Achille, S Deng, R Fonseca, M Pabon-Saldana, ... Blood advances 2 (21), 3012-3024, 2018 | 22 | 2018 |
| HDAC6 inhibition alleviates CLL-induced T-cell dysfunction and enhances immune checkpoint blockade efficacy in the Eμ-TCL1 model K Maharaj, JJ Powers, M Mediavilla-Varela, A Achille, W Gamal, S Quayle, ... Frontiers in Immunology 11, 590072, 2020 | 21 | 2020 |
| Differential regulation of human T-cells by TGR-1202, a novel PI3Kδ inhibitor KK Maharaj, J Powers, R Fonseca, H Miskin, D Maryanski, E Sahakian Cancer Res 76 (14 Supplement), 545, 2016 | 16 | 2016 |
| Regulatory T cells (Tregs) in lymphoid malignancies and the impact of novel therapies K Maharaj, A Uriepero, E Sahakian, J Pinilla-Ibarz Frontiers in Immunology 13, 943354, 2022 | 14 | 2022 |
| Histone deacetylase 6 (HDAC6) as a regulator of immune check-point molecules in chronic lymphocytic leukemia (CLL) JJ Powers, KK Maharaj, E Sahakian, L Xing, P PerezVillarroel, T Knox, ... Blood 124 (21), 3311, 2014 | 13 | 2014 |
| Modulation of T cell compartment in a preclinical CLL murine model by a selective PI3K delta inhibitor, TGR-1202 KK Maharaj, JJ Powers, M Pabon-Saldana, R Fonseca, A Achille, S Deng, ... Blood, The Journal of the American Society of Hematology 128 (22), 3236-3236, 2016 | 9 | 2016 |
| Differential regulation of T cells by PI3K delta inhibitors in a CLL murine model K Maharaj, JJ Powers, A Achille, M Pabon-Saldana, R Fonseca, S Deng, ... Blood 130, 3009, 2017 | 2 | 2017 |
| A phase I study of duvelisib in combination with oral azacitidine (CC-486) in relapsed lymphoid malignancies. H Saeed, E Sahakian, KK Maharaj, Q Mo, L Zhang, RJ Makanji, ... Journal of Clinical Oncology 40 (16_suppl), TPS7594-TPS7594, 2022 | 1 | 2022 |
| Characterization of T-cell metabolic defects in chronic lymphocytic leukemia preclinical model W Gamal, M Mediavilla-Varela, K Maharaj, A Uriepero, V Kunta, ... Cancer Research 83 (7_Supplement), 4843-4843, 2023 | | 2023 |
| Targeting Inflammatory Pathways to Reverse Immunosuppressive Tumor Microenvironment in Chronic Lymphocytic Leukemia A Uriepero, M Mediavilla-Varela, K Maharaj, W Gamal, ME Marquez, ... Blood 140 (Supplement 1), 6988-6989, 2022 | | 2022 |
| Metabolic Abnormalities Associated with T-Cell Exhaustion in CLL Eµ-TCL1 Murine Model W Gamal, M Mediavilla-Varela, K Maharaj, A Uriepero, V Kunta, ... Blood 140 (Supplement 1), 6994-6995, 2022 | | 2022 |
| Efficacy and immune profiling of PI3K delta inhibitor zandelisib (ME-401) in a preclinical chronic lymphocytic leukemia (CLL) model K Maharaj, M Mediavilla-Varela, JJ Powers, S Wiley, A Uriepero, ... Cancer Research 82 (12_Supplement), 5496-5496, 2022 | | 2022 |
| Efficacy of Vecabrutinib Treatment in a Murine Model of Sclerodermatous Graft-Versus-Host-Disease K Maharaj, M Mediavilla-Varela, A Uriepero, JA Fox, P Taverna, W Gamal, ... Blood 138, 1685, 2021 | | 2021 |
| Disruption of STAT3 signaling in CLL B cells through HDAC6 inhibition reverses CLL T-cell exhaustion K Maharaj, J Powers, A Achille, A Nieto, E Sahakian, J Pinilla-Ibarz LEUKEMIA & LYMPHOMA 61, 50-50, 2020 | | 2020 |
| Combinatorial efficacy of anti-PD1 treatment and selective histone deacetylase 6 (HDAC6) inhibition in chronic lymphocytic leukemia (CLL) K Maharaj, J Powers, A Achille, E Sahakian, J Pinilla-Ibarz Cancer Research 79 (13_Supplement), 4723-4723, 2019 | | 2019 |
| Enhancing Immunotherapeutic Interventions for Treatment of Chronic Lymphocytic Leukemia KK Maharaj | | 2019 |
| Enhancing Immunomodulatory Therapeutic Interventions for Chronic Lymphocytic Leukemia KK Maharaj University of South Florida, 2019 | | 2019 |
Eva Sahakian, Ph.DSenior Research Scientist Moffitt cancer center; Assistant Professor USF Morsani School of Medicine在 moffitt.org 的电子邮件经过验证
