A reductive aminase from Aspergillus oryzae GA Aleku, SP France, H Man, J Mangas-Sanchez, SL Montgomery, ... Nature chemistry 9 (10), 961-969, 2017 | 344 | 2017 |
Imine reductases (IREDs) J Mangas-Sanchez, SP France, SL Montgomery, GA Aleku, H Man, ... Current opinion in chemical biology 37, 19-25, 2017 | 237 | 2017 |
NAD (P) H‐dependent dehydrogenases for the asymmetric reductive amination of ketones: Structure, mechanism, evolution and application M Sharma, J Mangas‐Sanchez, NJ Turner, G Grogan Advanced Synthesis & Catalysis 359 (12), 2011-2025, 2017 | 124 | 2017 |
A mechanism for reductive amination catalyzed by fungal reductive aminases M Sharma, J Mangas-Sanchez, SP France, GA Aleku, SL Montgomery, ... ACS Catalysis 8 (12), 11534-11541, 2018 | 93 | 2018 |
Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines SP France, GA Aleku, M Sharma, J Mangas‐Sanchez, RM Howard, ... Angewandte Chemie International Edition 56 (49), 15589-15593, 2017 | 77 | 2017 |
Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases J Mangas-Sanchez, M Sharma, SC Cosgrove, JI Ramsden, JR Marshall, ... Chemical Science 11, 5052-5057, 2020 | 63 | 2020 |
New imine-reducing enzymes from β-hydroxyacid dehydrogenases by single amino acid substitutions M Lenz, S Fademrecht, M Sharma, J Pleiss, G Grogan, BM Nestl Protein Engineering, Design and Selection 31 (4), 109-120, 2018 | 42 | 2018 |
Asymmetric synthesis of primary and secondary β-fluoro-arylamines using reductive aminases from fungi GJ Grogan, M Sharma, A Cuetos, I Lavandera, V Gotor-Fernández, ... ChemCatChem, 2020 | 33 | 2020 |
Inverted binding of non-natural substrates in strictosidine synthase leads to a switch of stereochemical outcome in enzyme-catalyzed pictet–spengler reactions E Eger, A Simon, M Sharma, S Yang, WB Breukelaar, G Grogan, KN Houk, ... Journal of the American Chemical Society 142 (2), 792-800, 2020 | 33 | 2020 |
Substrate Anchoring and Flexibility Reduction in CYP153AM.aq Leads to Highly Improved Efficiency toward Octanoic Acid LR Rapp, SM Marques, E Zukic, B Rowlinson, M Sharma, G Grogan, ... ACS Catalysis 11 (5), 3182-3189, 2021 | 31 | 2021 |
Sulfoglycolysis: catabolic pathways for metabolism of sulfoquinovose AJD Snow, L Burchill, M Sharma, GJ Davies, SJ Williams Chemical Society Reviews, https://doi.org/10.1039/D1CS00846C, 2021 | 25 | 2021 |
Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria M Sharma, JP Lingford, M Petricevic, AJD Snow, Y Zhang, MA Järvå, ... Proceedings of the National Academy of Sciences 119 (4), e2116022119, 2022 | 22 | 2022 |
A sulfoglycolytic Entner-Doudoroff pathway in Rhizobium leguminosarum bv. trifolii SRDI565 J Li, R Epa, NE Scott, D Skoneczny, M Sharma, AJD Snow, JP Lingford, ... Applied and Environmental Microbiology 86 (15), e00750-20, 2020 | 22 | 2020 |
Molecular basis of sulfosugar selectivity in sulfoglycolysis M Sharma, P Abayakoon, R Epa, Y Jin, JP Lingford, T Shimada, ... ACS Central Science 7 (3), 476-487, 2021 | 20 | 2021 |
Dynamic structural changes accompany the production of dihydroxypropanesulfonate by sulfolactaldehyde reductase M Sharma, P Abayakoon, JP Lingford, R Epa, A John, Y Jin, ... ACS Catalysis 10 (4), 2826-2836, 2020 | 19 | 2020 |
Characterization and structure‐guided engineering of the novel versatile terpene monooxygenase CYP109Q5 from Chondromyces apiculatus DSM436 JM Klenk, P Dubiel, M Sharma, G Grogan, B Hauer Microbial Biotechnology 12 (2), 377-391, 2019 | 12 | 2019 |
Identification and characterization of cytochrome P450 1232A24 and 1232F1 from Arthrobacter sp. and their role in the metabolic pathway of papaverine JM Klenk, MP Fischer, P Dubiel, M Sharma, B Rowlinson, G Grogan, ... The journal of biochemistry 166 (1), 51-66, 2019 | 9 | 2019 |
Inverting the stereoselectivity of an NADH-dependent imine reductase variant P Stockinger, N Borlinghaus, M Sharma, B Aberle, G Grogan, J Pleiss, ... ChemCatChem, https://doi.org/10.1002/cctc.202101057, 2021 | 8 | 2021 |
Widespread Family of NAD+-Dependent Sulfoquinovosidases at the Gateway to Sulfoquinovose Catabolism A Kaur, IB Pickles, M Sharma, N Madeido Soler, NE Scott, SJ Pidot, ... Journal of the American Chemical Society 145 (51), 28216-28223, 2023 | 6 | 2023 |
Molecular basis of sulfolactate synthesis by sulfolactaldehyde dehydrogenase from Rhizobium leguminosarum J Li, M Sharma, R Meek, A Alhifthi, Z Armstrong, NM Soler, M Lee, ... Chemical Science 14 (41), 11429-11440, 2023 | 3 | 2023 |