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Tomáš Etrych
Tomáš Etrych
Research profesor, Institute of macromolecular chemistry
在 imc.cas.cz 的电子邮件经过验证
标题
引用次数
引用次数
年份
New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties
T Etrych, M Jelı́nková, B Řı́hová, K Ulbrich
Journal of Controlled Release 73 (1), 89-102, 2001
4252001
In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity
GM Lynn, R Laga, PA Darrah, AS Ishizuka, AJ Balaci, AE Dulcey, ...
Nature biotechnology 33 (11), 1201-1210, 2015
4202015
Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin
M Talelli, M Iman, AK Varkouhi, CJF Rijcken, RM Schiffelers, T Etrych, ...
Biomaterials 31 (30), 7797-7804, 2010
2932010
HPMA copolymers with pH-controlled release of doxorubicin: in vitro cytotoxicity and in vivo antitumor activity
K Ulbrich, T Etrych, P Chytil, M Jelınková, B Řı́hová
Journal of Controlled Release 87 (1-3), 33-47, 2003
2582003
Biodegradable star HPMA polymer–drug conjugates: Biodegradability, distribution and anti-tumor efficacy
T Etrych, L Kovář, J Strohalm, P Chytil, B Říhová, K Ulbrich
Journal of Controlled Release 154 (3), 241-248, 2011
1992011
New HPMA copolymer-based drug carriers with covalently bound hydrophobic substituents for solid tumour targeting
P Chytil, T Etrych, Č Koňák, M Šírová, T Mrkvan, J Bouček, B Říhová, ...
Journal of Controlled Release 127 (2), 121-130, 2008
1672008
Synthesis of HPMA copolymers containing doxorubicin bound via a hydrazone linkage. Effect of spacer on drug release and in vitro cytotoxicity
T Etrych, P Chytil, M Jelínková, B Říhová, K Ulbrich
Macromolecular bioscience 2 (1), 43-52, 2002
1672002
Antibody-targeted polymer–doxorubicin conjugates with pH-controlled activation
K Ulbrich, T Etrych, P Chytil, M Jelínková, B Říhová
Journal of drug targeting 12 (8), 477-489, 2004
1552004
HPMA copolymer conjugates of paclitaxel and docetaxel with pH-controlled drug release
T Etrych, M Šírová, L Starovoytova, B Říhová, K Ulbrich
Molecular pharmaceutics 7 (4), 1015-1026, 2010
1522010
Polymer‐coated polyethylenimine/DNA complexes designed for triggered activation by intracellular reduction
RC Carlisle, T Etrych, SS Briggs, JA Preece, K Ulbrich, LW Seymour
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2004
1522004
Nanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles, and liposomes
L Quan, Y Zhang, BJ Crielaard, A Dusad, SM Lele, CJF Rijcken, ...
ACS nano 8 (1), 458-466, 2014
1512014
Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers
T Lammers, R Kühnlein, M Kissel, V Subr, T Etrych, R Pola, M Pechar, ...
Journal of controlled release 110 (1), 103-118, 2005
1482005
Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy
M Talelli, S Oliveira, CJF Rijcken, EHE Pieters, T Etrych, K Ulbrich, ...
Biomaterials 34 (4), 1255-1260, 2013
1452013
Fluorescence optical imaging in anticancer drug delivery
T Etrych, H Lucas, O Janoušková, P Chytil, T Mueller, K Mäder
Journal of Controlled Release 226, 168-181, 2016
1432016
HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity
T Etrych, V Šubr, J Strohalm, M Šírová, B Říhová, K Ulbrich
Journal of controlled release 164 (3), 346-354, 2012
1432012
N-(2-Hydroxypropyl) methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT …
P Chytil, T Etrych, J Kříž, V Šubr, K Ulbrich
European journal of pharmaceutical sciences 41 (3-4), 473-482, 2010
1432010
Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes
B Rıhová, T Etrych, M Pechar, M Jelınková, M Štastný, O Hovorka, ...
Journal of controlled release 74 (1-3), 225-232, 2001
1392001
Noninvasive optical imaging of nanomedicine biodistribution
S Kunjachan, F Gremse, B Theek, P Koczera, R Pola, M Pechar, T Etrych, ...
ACS nano 7 (1), 252-262, 2013
1342013
N‐(2‐hydroxypropyl)methacrylamide‐based polymer conjugates with pH‐controlled activation of doxorubicin. I. New synthesis, physicochemical characterization …
T Etrych, T Mrkvan, P Chytil, Č Koňák, B Říhová, K Ulbrich
Journal of Applied Polymer Science 109 (5), 3050-3061, 2008
1222008
Conjugates of doxorubicin with graft HPMA copolymers for passive tumor targeting
T Etrych, P Chytil, T Mrkvan, M Šírová, B Říhová, K Ulbrich
Journal of Controlled Release 132 (3), 184-192, 2008
1202008
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