Structure and functionality in flavivirus NS-proteins: perspectives for drug design M Bollati, K Alvarez, R Assenberg, C Baronti, B Canard, S Cook, ... Antiviral research 87 (2), 125-148, 2010 | 443 | 2010 |
Cryo-electron microscopy reveals the functional organization of an enveloped virus, Semliki Forest virus EJ Mancini, M Clarke, BE Gowen, T Rutten, SD Fuller Molecular cell 5 (2), 255-266, 2000 | 280 | 2000 |
Atomic snapshots of an RNA packaging motor reveal conformational changes linking ATP hydrolysis to RNA translocation EJ Mancini, DE Kainov, JM Grimes, R Tuma, DH Bamford, DI Stuart Cell 118 (6), 743-755, 2004 | 191 | 2004 |
Crystal structure of a novel conformational state of the flavivirus NS3 protein: implications for polyprotein processing and viral replication R Assenberg, E Mastrangelo, TS Walter, A Verma, M Milani, RJ Owens, ... Journal of virology 83 (24), 12895-12906, 2009 | 182 | 2009 |
A procedure for setting up high-throughput nanolitre crystallization experiments. I. Protocol design and validation TS Walter, J Diprose, J Brown, M Pickford, RJ Owens, DI Stuart, K Harlos Journal of applied crystallography 36 (2), 308-314, 2003 | 114 | 2003 |
Mutations in TBX18 cause dominant urinary tract malformations via transcriptional dysregulation of ureter development A Vivante, MJ Kleppa, J Schulz, S Kohl, A Sharma, J Chen, S Shril, ... The American Journal of Human Genetics 97 (2), 291-301, 2015 | 92 | 2015 |
Structure of the leukemia oncogene LMO2: implications for the assembly of a hematopoietic transcription factor complex K El Omari, SJ Hoosdally, K Tuladhar, D Karia, P Vyas, R Patient, ... Blood, The Journal of the American Society of Hematology 117 (7), 2146-2156, 2011 | 89 | 2011 |
IRF4 in multiple myeloma—Biology, disease and therapeutic target A Agnarelli, T Chevassut, EJ Mancini Leukemia research 72, 52-58, 2018 | 69 | 2018 |
Structural basis for LMO2-driven recruitment of the SCL: E47bHLH heterodimer to hematopoietic-specific transcriptional targets K El Omari, SJ Hoosdally, K Tuladhar, D Karia, E Hall-Ponselé, ... Cell reports 4 (1), 135-147, 2013 | 68 | 2013 |
Hexameric molecular motors: P4 packaging ATPase unravels the mechanism DE Kainov, R Tuma, EJ Mancini Cellular and Molecular Life Sciences CMLS 63, 1095-1105, 2006 | 63 | 2006 |
High-resolution icosahedral reconstruction: fulfilling the promise of cryo-electron microscopy EJ Mancini, F de Haas, SD Fuller Structure 5 (6), 741-750, 1997 | 58 | 1997 |
A procedure for setting up high-throughput nanolitre crystallization experiments. II. Crystallization results J Brown, TS Walter, L Carter, NGA Abrescia, AR Aricescu, ... Journal of applied crystallography 36 (2), 315-318, 2003 | 54 | 2003 |
The docking interaction of caspase-9 with ERK2 provides a mechanism for the selective inhibitory phosphorylation of caspase-9 at threonine 125 MC Martin, LA Allan, EJ Mancini, PR Clarke Journal of biological chemistry 283 (7), 3854-3865, 2008 | 51 | 2008 |
Concerted action of the PHD, chromo and motor domains regulates the human chromatin remodelling ATPase CHD4 R Morra, BM Lee, H Shaw, R Tuma, EJ Mancini FEBS letters 586 (16), 2513-2521, 2012 | 48 | 2012 |
Plate tectonics of virus shell assembly and reorganization in phage φ8, a distant relative of mammalian reoviruses K El Omari, G Sutton, JJ Ravantti, H Zhang, TS Walter, JM Grimes, ... Structure 21 (8), 1384-1395, 2013 | 46 | 2013 |
Structural basis of mechanochemical coupling in a hexameric molecular motor DE Kainov, EJ Mancini, J Telenius, J Lisal, JM Grimes, DH Bamford, ... Journal of biological chemistry 283 (6), 3607-3617, 2008 | 46 | 2008 |
The first step: activation of the Semliki Forest virus spike protein precursor causes a localized conformational change in the trimeric spike I Ferlenghi, B Gowen, F de Haas, EJ Mancini, H Garoff, M Sjöberg, ... Journal of molecular biology 283 (1), 71-81, 1998 | 45 | 1998 |
Semi-automated microseeding of nanolitre crystallization experiments TS Walter, EJ Mancini, J Kadlec, SC Graham, R Assenberg, J Ren, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2008 | 42 | 2008 |
Structure of the Murray Valley encephalitis virus RNA helicase at 1.9 Å resolution EJ Mancini, R Assenberg, A Verma, TS Walter, R Tuma, JM Grimes, ... Protein science 16 (10), 2294-2300, 2007 | 37 | 2007 |
Tracking in atomic detail the functional specializations in viral RecA helicases that occur during evolution K El Omari, C Meier, D Kainov, G Sutton, JM Grimes, MM Poranen, ... Nucleic acids research 41 (20), 9396-9410, 2013 | 30 | 2013 |