Extensive chromatin remodelling and establishment of transcription factor ‘hotspots’ during early adipogenesis R Siersbæk, R Nielsen, S John, MH Sung, S Baek, A Loft, GL Hager, ... The EMBO journal 30 (8), 1459-1472, 2011 | 384 | 2011 |
Transcription factor cooperativity in early adipogenic hotspots and super-enhancers R Siersbæk, A Rabiee, R Nielsen, S Sidoli, S Traynor, A Loft, ... Cell reports 7 (5), 1443-1455, 2014 | 255 | 2014 |
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers A Loft, I Forss, MS Siersbæk, SF Schmidt, ASB Larsen, JGS Madsen, ... Genes & development 29 (1), 7-22, 2015 | 151 | 2015 |
Genome-wide profiling of peroxisome proliferator-activated receptor γ in primary epididymal, inguinal, and brown adipocytes reveals depot-selective binding correlated with gene … MS Siersbæk, A Loft, MM Aagaard, R Nielsen, SF Schmidt, N Petrovic, ... Molecular and cellular biology, 2012 | 138 | 2012 |
Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication A Loft, AJ Alfaro, SF Schmidt, FB Pedersen, MK Terkelsen, M Puglia, ... Cell metabolism 33 (8), 1685-1700. e9, 2021 | 102 | 2021 |
RNA-seq and mass-spectrometry-based lipidomics reveal extensive changes of glycerolipid pathways in brown adipose tissue in response to cold AB Marcher, A Loft, R Nielsen, T Vihervaara, JGS Madsen, M Sysi-Aho, ... Cell reports 13 (9), 2000-2013, 2015 | 93 | 2015 |
Acute TNF-induced repression of cell identity genes is mediated by NFκB-directed redistribution of cofactors from super-enhancers SF Schmidt, BD Larsen, A Loft, R Nielsen, JGS Madsen, S Mandrup Genome research 25 (9), 1281-1294, 2015 | 85 | 2015 |
iRNA-seq: computational method for genome-wide assessment of acute transcriptional regulation from total RNA-seq data JGS Madsen, SF Schmidt, BD Larsen, A Loft, R Nielsen, S Mandrup Nucleic acids research 43 (6), e40-e40, 2015 | 70 | 2015 |
High‐protein diet more effectively reduces hepatic fat than low‐protein diet despite lower autophagy and FGF21 levels C Xu, M Markova, N Seebeck, A Loft, S Hornemann, T Gantert, S Kabisch, ... Liver International 40 (12), 2982-2997, 2020 | 65 | 2020 |
The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation ASB Brier, A Loft, JGS Madsen, T Rosengren, R Nielsen, SF Schmidt, ... Nucleic acids research 45 (4), 1743-1759, 2017 | 58 | 2017 |
Cofactor squelching: Artifact or fact? SF Schmidt, BD Larsen, A Loft, S Mandrup Bioessays 38 (7), 618-626, 2016 | 52 | 2016 |
A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis A Loft, SF Schmidt, G Caratti, U Stifel, J Havelund, R Sekar, Y Kwon, ... Cell Metabolism 34 (3), 473-486. e9, 2022 | 42 | 2022 |
Integrative genomics outlines a biphasic glucose response and a ChREBP-RORγ axis regulating proliferation in β cells SF Schmidt, JGS Madsen, KØ Frafjord, L la Cour Poulsen, S Salö, ... Cell reports 16 (9), 2359-2372, 2016 | 41 | 2016 |
Hormesis enables cells to handle accumulating toxic metabolites during increased energy flux J Zemva, CA Fink, TH Fleming, L Schmidt, A Loft, S Herzig, RA Knieß, ... Redox Biology 13, 674-686, 2017 | 36 | 2017 |
Genome-wide insights into the development and function of thermogenic adipocytes A Loft, I Forss, S Mandrup Trends in Endocrinology & Metabolism 28 (2), 104-120, 2017 | 36 | 2017 |
Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism S Pearson, A Loft, P Rajbhandari, J Simcox, S Lee, P Tontonoz, ... Genes & development 33 (13-14), 747-762, 2019 | 33 | 2019 |
Hypoxia-inducible lipid droplet–associated Is not a direct physiological regulator of lipolysis in adipose tissue W Dijk, F Mattijssen, M de la Rosa Rodriguez, A Loza Valdes, A Loft, ... Endocrinology 158 (5), 1231-1251, 2017 | 30 | 2017 |
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity S Seitz, Y Kwon, G Hartleben, J Jülg, R Sekar, N Krahmer, B Najafi, A Loft, ... Nature Metabolism 1 (10), 1009-1026, 2019 | 29 | 2019 |
Modulating the genomic programming of adipocytes A Loft, SF Schmidt, S Mandrup Cold Spring Harbor symposia on quantitative biology 80, 239-248, 2015 | 7 | 2015 |
Fasting‐sensitive SUMO‐switch on Prox1 controls hepatic cholesterol metabolism AJ Alfaro, C Dittner, J Becker, A Loft, A Mhamane, A Maida, A Georgiadi, ... EMBO reports 24 (10), e55981, 2023 | 3 | 2023 |