Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications D Mathew, JR Giles, AE Baxter, DA Oldridge, AR Greenplate, JE Wu, ... Science 369 (6508), eabc8511, 2020 | 1570 | 2020 |
Comprehensive mapping of immune perturbations associated with severe COVID-19 L Kuri-Cervantes, MB Pampena, W Meng, AM Rosenfeld, CAG Ittner, ... Science immunology 5 (49), eabd7114, 2020 | 773 | 2020 |
mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern RR Goel, MM Painter, SA Apostolidis, D Mathew, W Meng, AM Rosenfeld, ... Science 374 (6572), abm0829, 2021 | 732 | 2021 |
Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccination RR Goel, SA Apostolidis, MM Painter, D Mathew, A Pattekar, O Kuthuru, ... Science immunology 6 (58), eabi6950, 2021 | 646 | 2021 |
Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy DB Johnson, MV Estrada, R Salgado, V Sanchez, DB Doxie, SR Opalenik, ... Nature communications 7 (1), 10582, 2016 | 529 | 2016 |
Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy SA Apostolidis, M Kakara, MM Painter, RR Goel, D Mathew, K Lenzi, ... Nature medicine 27 (11), 1990-2001, 2021 | 438 | 2021 |
CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer EM Bange, NA Han, P Wileyto, JY Kim, S Gouma, J Robinson, ... Nature medicine 27 (7), 1280-1289, 2021 | 428 | 2021 |
Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection EM Anderson, EC Goodwin, A Verma, CP Arevalo, MJ Bolton, ME Weirick, ... Cell 184 (7), 1858-1864. e10, 2021 | 396 | 2021 |
Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination MM Painter, D Mathew, RR Goel, SA Apostolidis, A Pattekar, O Kuthuru, ... Immunity 54 (9), 2133-2142. e3, 2021 | 380 | 2021 |
Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma PJ Siska, KE Beckermann, FM Mason, G Andrejeva, AR Greenplate, ... JCI insight 2 (12), 2017 | 306 | 2017 |
High-throughput mapping of B cell receptor sequences to antigen specificity I Setliff, AR Shiakolas, KA Pilewski, AA Murji, RE Mapengo, K Janowska, ... Cell 179 (7), 1636-1646. e15, 2019 | 247 | 2019 |
Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19 LA Vella, JR Giles, AE Baxter, DA Oldridge, C Diorio, L Kuri-Cervantes, ... Science immunology 6 (57), eabf7570, 2021 | 200 | 2021 |
Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine RR Goel, MM Painter, KA Lundgreen, SA Apostolidis, AE Baxter, JR Giles, ... Cell 185 (11), 1875-1887. e8, 2022 | 166 | 2022 |
SARS-CoV-2 seroprevalence among parturient women in Philadelphia DD Flannery, S Gouma, MB Dhudasia, S Mukhopadhyay, MR Pfeifer, ... Science immunology 5 (49), eabd5709, 2020 | 148 | 2020 |
Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation MS Abdel-Hakeem, S Manne, JC Beltra, E Stelekati, Z Chen, K Nzingha, ... Nature immunology 22 (8), 1008-1019, 2021 | 145 | 2021 |
Tumor-associated macrophages promote invasion while retaining Fc-dependent anti-tumor function KD Grugan, FL McCabe, M Kinder, AR Greenplate, BC Harman, JE Ekert, ... The Journal of Immunology 189 (11), 5457-5466, 2012 | 132 | 2012 |
Proteolytic cleavage and loss of function of biologic agents that neutralize tumor necrosis factor in the mucosa of patients with inflammatory bowel disease P Biancheri, RJ Brezski, A Di Sabatino, AR Greenplate, KL Soring, ... Gastroenterology 149 (6), 1564-1574. e3, 2015 | 123 | 2015 |
In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer Z Chen, E Arai, O Khan, Z Zhang, SF Ngiow, Y He, H Huang, S Manne, ... Cell 184 (5), 1262-1280. e22, 2021 | 122 | 2021 |
Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals K Lederer, E Bettini, K Parvathaneni, MM Painter, D Agarwal, ... Cell 185 (6), 1008-1024. e15, 2022 | 116 | 2022 |
Single cell analysis of human tissues and solid tumors with mass cytometry N Leelatian, DB Doxie, AR Greenplate, BC Mobley, JM Lehman, ... Cytometry Part B: Clinical Cytometry 92 (1), 68-78, 2017 | 112 | 2017 |