Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies IJ Findlay, GN De Iuliis, RJ Duchatel, ER Jackson, NA Vitanza, JE Cain, ... Oncogene 41 (4), 461-475, 2022 | 60 | 2022 |
Can hemp help? Low-THC cannabis and non-THC cannabinoids for the treatment of cancer F Afrin, M Chi, AL Eamens, RJ Duchatel, AM Douglas, J Schneider, ... Cancers 12 (4), 1033, 2020 | 60 | 2020 |
Signal transduction in diffuse intrinsic pontine glioma RJ Duchatel, ER Jackson, F Alvaro, B Nixon, H Hondermarck, MD Dun Proteomics 19 (21-22), 1800479, 2019 | 52 | 2019 |
Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways S Venneti, AR Kawakibi, S Ji, SM Waszak, SR Sweha, M Mota, M Pun, ... Cancer discovery 13 (11), 2370-2393, 2023 | 40 | 2023 |
Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma RJ Duchatel, A Mannan, AS Woldu, T Hawtrey, PA Hindley, AM Douglas, ... Neuro-oncology advances 3 (1), vdab169, 2021 | 39 | 2021 |
Increased white matter neuron density in a rat model of maternal immune activation—implications for schizophrenia RJ Duchatel, P Jobling, BA Graham, LR Harms, PT Michie, DM Hodgson, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 65, 118-126, 2016 | 35 | 2016 |
ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma ER Jackson, RJ Duchatel, DE Staudt, ML Persson, A Mannan, S Yadavilli, ... Cancer research 83 (14), 2421-2437, 2023 | 32 | 2023 |
White matter neuron biology and neuropathology in schizophrenia RJ Duchatel, C Shannon Weickert, PA Tooney npj Schizophrenia 5 (1), 10, 2019 | 32 | 2019 |
Shwachman–Bodian–Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia MD Dun, A Mannan, CJ Rigby, S Butler, HD Toop, D Beck, P Connerty, ... Leukemia 34 (12), 3393-3397, 2020 | 18 | 2020 |
Increased complement component 4 (C4) gene expression in the cingulate cortex of rats exposed to late gestation immune activation RJ Duchatel, CL Meehan, LR Harms, PT Michie, MJ Bigland, DW Smith, ... Schizophrenia research 199, 442-444, 2018 | 17 | 2018 |
B-cell lymphoma 6 (BCL6): from master regulator of humoral immunity to oncogenic driver in pediatric cancers T McLachlan, WC Matthews, ER Jackson, DE Staudt, AM Douglas, ... Molecular Cancer Research 20 (12), 1711-1723, 2022 | 15 | 2022 |
Late gestation immune activation increases IBA1-positive immunoreactivity levels in the corpus callosum of adult rat offspring RJ Duchatel, CL Meehan, LR Harms, PT Michie, MJ Bigland, DW Smith, ... Psychiatry research 266, 175-185, 2018 | 14 | 2018 |
A review of current therapeutics targeting the mitochondrial protease ClpP in diffuse midline glioma, H3 K27-altered ER Jackson, ML Persson, CJ Fish, IJ Findlay, S Mueller, J Nazarian, ... Neuro-oncology 26 (Supplement_2), S136-S154, 2024 | 12* | 2024 |
PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma RJ Duchatel, ER Jackson, SG Parackal, D Kiltschewskij, IJ Findlay, ... The Journal of clinical investigation 134 (6), 2024 | 12* | 2024 |
Blockade of ROS production inhibits oncogenic signaling in acute myeloid leukemia and amplifies response to precision therapies ZP Germon, JR Sillar, A Mannan, RJ Duchatel, D Staudt, HC Murray, ... Science Signaling 16 (778), eabp9586, 2023 | 10 | 2023 |
Reduced cortical somatostatin gene expression in a rat model of maternal immune activation RJ Duchatel, LR Harms, CL Meehan, PT Michie, MJ Bigland, DW Smith, ... Psychiatry Research 282, 112621, 2019 | 10 | 2019 |
A road map for the treatment of pediatric diffuse midline glioma C Koschmann, WN Al-Holou, MM Alonso, J Anastas, P Bandopadhayay, ... Cancer cell 42 (1), 1-5, 2024 | 4 | 2024 |
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection DE Staudt, HC Murray, DA Skerrett-Byrne, ND Smith, MFB Jamaluddin, ... Clinical Proteomics 19 (1), 48, 2022 | 3 | 2022 |
Current status and advances to improving drug delivery in diffuse intrinsic pontine glioma LM Arms, RJ Duchatel, ER Jackson, PG Sobrinho, MD Dun, S Hua Journal of Controlled Release 370, 835-865, 2024 | | 2024 |